Direct-to-consumer marketing
Marketing to humans who are ready for your brand.
We align your DTC campaigns to clinical realities along the care journey, protecting privacy without sacrificing performance.
When you start with patient outcomes, everything else gets easier.
We set the standard for privacy-safe, data-driven DTC. Reach the highest priority patients, wherever they are.
With us, you can...
Build precise audiences
We pick up eligibility signals at a local level, combining healthcare claims and consumer context.
Do omnichannel right
No more silos. We coordinate messaging across touchpoints so education and access build momentum.
Protect privacy by design
Our approach relies on privacy-safe and hyperlocal data rather than cookies or profiles.
Prove campaign performance
Our measurement links exposure to action, giving teams clearer signals for media efficiency and repeatable wins.
Accelerate speed to therapy
By addressing education, eligibility, and affordability, campaigns help shorten the path to therapy start.
Make every dollar count by reaching eligible patients wherever they are.
We build DTC for the space between symptoms and the appointment, where relevance matters most. That’s why our programmatic activation is guided by care-based signals, not inferred intent.
Audio
Audio with OptimizeRx allows life science brands to connect with patients while they are listening to podcasts, streaming music, or tuning into broadcast radio. Powered by our patented Micro-Neighborhood® Technology (MNT), audio campaigns reach hyperlocal patient clusters with clinical and geographic specificity at the zip-9 level.
This ensures your brand message resonates during daily routines when screens are off, providing a privacy-safe, HIPAA-compliant way to reinforce brand awareness and education.
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CTV
Connected TV (CTV/OTT) with OptimizeRx brings the precision of digital targeting to the living room screen. Powered by our patented Micro-Neighborhood® Technology (MNT), CTV campaigns reach hyperlocal patient clusters with clinical and geographic specificity at the zip-9 level. This allows life science brands to deliver high-impact, educational video content to brand-eligible audiences in a privacy-safe, HIPAA-compliant manner while they stream their favorite television shows and movies.
Capture patient attention when they are highly engaged and receptive. Connected TV combines the premium storytelling power of television with data-driven precision, helping move patients from initial symptom curiosity to active consideration of your therapy.
Direct Mail
Direct Mail with OptimizeRx gives brands access to a tangible, non-digital deployment option to engage high-quality consumer audiences with precision and maximize impact.
Designed for Direct-to-Consumer (DTC) engagement, our Direct Mail solution leverages Micro-Neighborhood® Technology (MNT) curated against self-identified, double opt-in audiences at the hyperlocal level. The result is a trusted, privacy-safe audience of targetable addresses that can reinforce digital campaigns, strengthen brand connections, and drive conversion.
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Email Messaging with OptimizeRx is designed for Direct-to-Consumer (DTC) engagement, leveraging our proprietary Micro-Neighborhood® Technology (MNT) curated against self-identified, double opt-in audiences at the hyperlocal level. As part of a broader multichannel strategy, email serves as a tangible reinforcement layer—deepening patient awareness, engagement, and action.
Leverage high-quality, opt-in audiences curated with clinical precision—reinforcing your brand message across channels while driving measurable consumer engagement.
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Linear
Data-Driven Linear (DDL) with OptimizeRx turns traditional TV into a more precise, data-driven channel for life science brands. Using our proprietary Micro-Neighborhood® Technology (MNT), campaigns are powered by clinically relevant, deterministic data to improve targeting.
By aligning verified patient clusters with specific geographies and viewing households, DDL helps brands reach their ideal consumer audiences while still benefiting from the broad scale of traditional linear TV.
Online Video
Online Video (OLV) with OptimizeRx leverages the storytelling power of sight, sound, and motion to help move patients from initial curiosity to real brand consideration.
Powered by our patented Micro-Neighborhood® Technology (MNT), OLV campaigns reach hyperlocal patient clusters with clinical and geographic specificity at the zip-9 level. This ensures your video content reaches even the hardest-to-find, brand-eligible audiences across the digital ecosystem in a privacy-safe, HIPAA-compliant manner.
Out of Home
Out-of-Home (OOH) with OptimizeRx unlocks high-impact visual advertising across a wide variety of formats and locations—including static and digital billboards, transit advertising, street furniture, gas station TVs, airports, and more.
Powered by OptimizeRx’s proprietary Micro-Neighborhood® Technology (MNT), OOH campaigns are activated with the same deterministic, privacy-safe methodology used across our digital solutions. This ensures your brand reaches the right patient clusters in the real-world environments where they live, travel, and make decisions, turning OOH into a clinically relevant, data-driven channel.
Programmatic
OptimizeRx brings precision and performance to DTC programmatic marketing. Using deterministic healthcare data, we help brands reach high-value patient audiences with relevant, compliant messaging across digital channels.
By synchronizing programmatic activation with broader omnichannel strategies—including HCP engagement—we ensure every impression works harder, driving more meaningful engagement and measurable impact on patient behavior.
Social
Social Messaging with OptimizeRx brings much-needed precision audience targeting to social platforms by focusing on who should actually see your message, rather than just how many people can.
Powered by our proprietary Micro-Neighborhood® Technology (MNT), our audiences connect your brand with highly relevant, brand-eligible consumers directly in their social feeds. This creates powerful, privacy-safe reach to drive condition education, reinforce messaging, and accelerate the path to therapy.
DTC Resources
Blog
Beyond Demographics: Deeper Audience Intelligence in Healthcare Marketing
Discover how more robust audience intelligence can improve healthcare media strategies, with real results from OptimizeRx's SAD analysis.
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Whitepaper
Pharma TV Advertising – Myth Vs. Reality
For educational power and nationwide reach, no other channel compares to television. But pharma may be making unnecessary tradeoffs that limit campaign impact. This infographic explores the most common myths that hold marketers back—and the solutions at brands' fingertips.
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Webinar
Everywhere That Matters: Rethinking Omnichannel Strategy in Pharma
Omnichannel is the buzzword—but precision should be the real goal of pharma marketing strategies.
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Make every dollar count by reaching eligible patients wherever they are.
Agencies
Your trusted partner for driving innovation and better performance for your clients.
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Life Sciences
From self-service audiences to synchronized patient-centric marketing — we deliver impact.
Publishers
Drive pharma ad revenue through privacy-safe, superior audience performance.
Partners
We partner with industry leading organizations.
Results that speak for themselves.
From rare disease to mass markets, our clients move faster, waste less, and turn coordinated marketing into measurable script lift.
Data Driven Decision-Making Drove 10:1 Return on TV Ad Spend
Learn how data-driven decision making in pharma delivered a 10:1 ROI on TV ad spend through precise targeting and omnichannel engagement.
The ad ranked in the top 25% for impressions per new prescriptions (NRx) generated.
Return on Advertising Spend (ROAS) Digital Display
Audience segments ranked in the top one-third for impressions per NRx generated.
AI-Powered EHR Messaging Drives Significant Referrals for Rare Disease Treatment Referral
Discover how AI in HCP engagement improved rare disease referrals by delivering timely, EHR-based education to pediatricians and specialists.
Higher Overall Referral Rate in the test group compared to the control group.
Increase in Pediatric Endocrinology Referrals in the test group versus the control group.
Increase in Pediatric Genetics Referrals in the test group
Improving Audience Quality for CTV with Clinical Connected Datasets
See how OptimizeRx drove ROI in pharma CTV advertising by using clinical data and Micro-Neighborhood® targeting to improve audience quality.
OptimizeRx targeting had the best performance of all partners in both audience quality and cost per diagnosed patient
Our Micro-Neighborhood® targeting platform produced higher audience quality than the national benchmark
Higher audience quality rate than the next performing partner
Healthcare marketing is evolving.
Ready for more than just a data vendor?
Explore our other marketing capabilities
Synchronized marketing
Bring HCP and DTC together, on your terms.
HCP marketing
Marketing to humans who just so happen to be clinicians.
The questions we get from teams marketing to patients.
These answers cover how we help brands find the right people, earlier and without guesswork or risk.
DTC pharma marketing solutions help brands reach patients with clinically relevant messaging across digital and traditional channels. OptimizeRx delivers privacy-safe, activation-ready, audiences using clinical data, media preference data, and consumer attributes to drive outcomes such as audience quality, new patient starts, script lift, and faster path to therapy.
OptimizeRx protects patient privacy by design using our patented Micro-Neighborhood® Technology (MNT). MNT aggregates de-identified medical claims and behavioral data to create hyper-local patient populations, enabling precise targeting based on real clinical signals without relying on cookies, inferred intent, or individual profiling, ensuring compliance and maintaining audience quality.
OptimizeRx builds DTC audience segments using clinical and behavioral data, including de-identified medical claims, diagnosis patterns, and patient health signals. These datasets are aggregated into privacy-safe Micro-Neighborhood® populations, allowing brands to reach patients most likely to benefit from therapy while maintaining full HIPAA and MHMD compliance.
OptimizeRx identifies brand-eligible patients using Micro-Neighborhood® Technology (MNT), which maps hyper-local, privacy-safe patient populations based on clinical signals and behavioral data. This enables brands to target the right patients across multiple channels—from programmatic, social, and CTV to email, direct mail, and point-of-care—while ensuring messaging is clinically relevant, compliant, and measurable.