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Appalachia, Southeast Hit Hardest by Obesity and Diabetes

November 19, 2009
CDC county-by-county analysis finds some areas with 1 in 10 adults already diabetic. While rates of obesity are climbing across America, they are especially high in sections of Appalachia and the Southeast, the U.S. Centers for Disease Control and Prevention reports in its first county-by-county survey.

Too Few Older Adults Get Recommended Screenings

November 19, 2009
Report looks to improve health of this group with better preventive care. Screening for cancer and other preventive health measures can prolong lives, but only 25 percent of adults aged 50 to 64 in the United States are getting these recommended screenings, a new report shows.

Prepared by the U.S.

Task Force Member Defends Mammography Guidelines

November 19, 2009
Meanwhile, three doctors weigh in on what women should do about the new recommendations. Responding to the uproar over revised mammogram recommendations unveiled earlier this week, a member of the independent task force that crafted the recommendations defended them Thursday, saying they were based on the most current, accurate information available.

Dr. Timothy Wilt, a member of the U.

Spray May Delay Ejaculation

November 19, 2009
Using five minutes before intercourse significantly postponed orgasm, study finds. A spray touted as the first potential treatment for premature ejaculation has proved effective in a second study, according to the company that developed it.

PSD502 .

Great American Smokeout '09

Time to Quit

November 19, 2009
American Cancer Society sets Nov. 19 as annual day to 'butt out' for good. The less you smoke, the more birthdays you'll have, says the American Cancer Society as it encourages smokers to quit on Thursday, the day of the 34th Great American Smokeout.

Research shows that smokers who quit at age 35 gain an average of eight years of life expectancy, and those who quit at 55 gain about five years. Even long-time smokers who quit at age 65 gain three years.

Genital Herpes May Never Go Dormant

November 18, 2009
Study finds low level shedding may be continuous, infection state unclear. Herpes, the sexually transmitted disease that causes genital lesions, never truly goes into a dormant state, new research suggests.

As a matter of fact, even when it's not causing an outbreak, the virus is shedding tiny bits of itself in the genital tract.

While the study did not specifically address whether or not the very small amounts of virus being continually shed are enough to infect someone else, the findings have the potential to change the way in which scientists view the life cycle of the disease.

MS Need Not Preclude Pregnancy

November 18, 2009
Study finds complications no greater overall than for other women. New research suggests that having multiple sclerosis puts pregnant women at slightly higher risk for giving birth via cesarean deliveries or having babies that grow at a slower rate in the womb.

But the researchers, whose findings were published online Nov. 18 in Neurology, also reported that pregnant women with MS were not more likely than other women to develop such conditions as preeclampsia or premature rupture of membranes.

Lifelong Exercise Keeps Seniors Young at Heart

November 18, 2009
Separate study finds stem cell therapy improves exercise capacity in patients with enlarged hearts. Lifelong exercise helps seniors keep their hearts healthy, new research shows.

The study included healthy people over age 65 .

Morphine May Help Tumors Spread in Cancer Patients

November 18, 2009
Lab study finds that common surgical painkillers help cancer cells thrive. Two new studies add to growing evidence that morphine and other opiate-based painkillers may promote the growth and spread of cancer cells.

The papers, scheduled to be presented Wednesday at an international cancer conference in Boston, also demonstrate how preventing opiates from reaching lung cancer cells reduces cancer cell proliferation, invasion and migration.

The findings from tests with cell cultures and mice suggest that the mu opiate receptor .

Mammography

What to Do Now?

November 18, 2009
Three doctors weigh in on what women should do about the new guidelines. When a U.S. government task force recommended that women wait until they're 50 to get their first mammogram to check for breast cancer, reaction was swift.

Heartburn Drugs Can Thwart Popular Blood Thinner

November 17, 2009
Combination can increase the risk of heart attack and stroke, U.S. officials say. Combining the antacid Prilosec with the popular blood thinner Plavix (clopidogrel) can cut the effectiveness of Plavix by half, putting patients at risk for heart attack or stroke, U.S. health officials said Tuesday.

Folic Acid Fortification Might Boost Cancer Risk

November 17, 2009
Norwegian study found supplementation raised chances of disease by 21%. Although folic acid fortification of foods can prevent many birth defects, it may also increase the risk for developing cancer, Norwegian researchers report.

Since 1998, many countries have mandated folic acid (vitamin B9) fortification of foods to decrease the incidence of neural-tube defects in newborns. By October 2009, the flour produced in these countries, plus the flour that is fortified voluntarily, represented 30 percent of the world's wheat flour produced in large mills.

Qutenza Approved for Post-Shingles Nerve Pain

November 17, 2009
Active ingredient is found in chili peppers The Qutenza (capsaicin) skin patch has been approved by the U.S. Food and Drug Administration to treat pain due to postherpetic neuralgia (PHN), the nerve pain that may follow shingles, drug maker NeurogesX said in a news release.

Guidelines Delay Start of Mammograms to Age 50, Then Every Other Year

November 16, 2009
Cancer Society, others voice strong disapproval of federal recommendations. Women don't need to start having mammograms to screen for breast cancer until they're 50, and they only need to have those exams every other year, new government guidelines suggest.

Also, breast self-exams, which women have been urged to do routinely, have not helped lower the death rate from breast cancer, the guidelines add.

Not all agree with the revised recommendations, however.

Teen Girls at Higher Risk for STDs

Report

November 16, 2009
Improved access to treatment for chlamydia, gonorrhea, syphilis is 'imperative,' expert says. Teen girls aged 15 to 19 accounted for the largest number (409,531) of the 1.5 million reported chlamydia and gonorrhea cases in the United States in 2008, followed by women aged 20 to 24, according to an annual federal report released Monday.

The researchers also found that black females continue to have a higher rate of sexually transmitted diseases (STDs) than any other racial or ethnic group.

Immunity to Swine Flu May Be Broader Than Thought

November 16, 2009
And that may explain why the disease hasn't posed more problems, study says. The swine flu virus that's sweeping across the United States isn't a total stranger to your immune system, a new study shows .

Lysteda Approved for Heavy Menstrual Bleeding

November 16, 2009
Designed to help blood to clot Tranexamic acid (Lysteda) has been approved by the U.S. Food and Drug Administration as the first non-hormonal drug to treat heavy menstrual bleeding, a medical condition called menorrhagia.

Study Touts Success With 'Female Viagra' Drug

November 16, 2009
Sexual desire improves in women taking flibanserin, expert says. New industry-funded research suggests that the antidepressant flibanserin, which has been touted as a female version of Viagra, can enhance libido in women with low sex drives.

The research compiles the results of several trials, the first to test a treatment for low libido in women that works on the brain, lead investigator Dr. John M.

Gene Linked to Breast Cancer Might Boost Heart Health

November 16, 2009
When BRCA1 is deactivated, it can lead to atherosclerosis, or hardening of the arteries, mouse study suggests. The over-activity of a gene known to boost a woman's risk for breast cancer may have a good side, making arteries healthier, a new study suggests.

The study, performed in mice, also found that when this gene, called BRCA1, is turned off, it promotes an inflammation that can lead to atherosclerosis or hardening of the arteries.

Although there has been no previous observation of increased cardiovascular death specifically in the large number of people who carry the BRCA1 mutation, there has been a surprising suggestion of higher non-cancer death in this population, noted study senior author Dr.

Sudden Cardiac Death Much More Likely to Strike Men

November 16, 2009
Males have triple the odds than women, study finds, and black men are especially prone. Men, especially black men, are at a relatively high risk of sudden cardiac death over their lifetime compared to women, a new study finds.

That lifetime risk in men aged 40 and over is one in eight, or 12.3 percent .

Gestures Processed in Brain's Language Center

November 14, 2009
Talking with your hands could be linked to evolution, research suggests. Words and gestures are processed in the same areas of the brain, a finding that may improve understanding of the evolution of language, researchers say.

In the study, MRI was used to monitor the brain activity of 20 volunteers as they watched video clips of a person either acting out gestures or voicing phrases that matched the gestures' meanings. Both the gestures and words triggered high levels of activity in the inferior frontal and posterior temporal areas, which are the language regions of the brain.

Another Swine Flu Vaccine Approved for Children

November 13, 2009
CSL's shot now for ages 6 months and older CSL Limited's H1N1 influenza vaccine has been approved by the U.S. Food and Drug Administration to include children 6 months and older, the agency said.

FDA Questions Safety of Caffeinated Alcoholic Drinks

November 13, 2009
Companies asked to show proof of safety and lawfulness of selling such beverages. Federal health officials said Friday that they plan to look into the safety and legality of making and selling popular alcohol drinks that contain caffeine.

Prompted by a request from several states' attorneys general, the U.S.

Web Giants Urge FDA to Update Ad Guidelines

November 13, 2009
Google and Yahoo join forces with drug makers at Internet marketing hearing. Internet giants Google and Yahoo have lined up with the pharmaceutical industry in asking the U.S. government to draft new rules that would give drug companies more latitude to advertise online.

Chinese Scientists Develop Database on the Liver

November 13, 2009
Information on proteins could help guide treatments for hepatitis and more. Chinese scientists report that they have created an extensive database about proteins produced by genes in the human liver, an endeavor they say could become the foundation for new treatments for liver disease.

To develop the database, reportedly the largest of its kind for any organ, the researchers examined 10 liver-tissue samples from volunteers and identified 6,788 proteins, half of which had never before been encountered. One unexplained discovery, they said, was that many seem to be connected to diseases of the nervous system.

22 Million Sickened by Swine Flu in 6 Months

November 12, 2009
Revised estimation method gives clearer picture of pandemic, CDC says. At least 22 million Americans have come down with the H1N1 swine flu since the virus first surfaced in April and approximately 3,900 people have died, including an estimated 540 children, federal health officials reported Thursday.

While these numbers represent a significant jump in the numbers of sick, hospitalized and dead from previous figures, they don't mean that the swine flu has suddenly gotten worse. Instead, the new numbers are based on extrapolations from laboratory-confirmed cases of swine flu.

Lab Study Slows Breast Cancer Spread to Bone in Mice

November 12, 2009
Experimental drug may lead to therapy that inhibits metastasis, research suggests. An experimental drug reduced the spread of breast cancer into bone in mice, researchers say.

The drug .

Progress in Stamping Out Smoking Has Stalled

November 12, 2009
1 in 5 Americans still smoke, CDC says, and numbers haven't moved in last 5 years. After decades of progress, the number of Americans who smoke hasn't budged over the last five years and actually rose slightly from 2007 to 2008, according to a new report from the U.S. Centers for Disease Control and Prevention.

Less HRT, Fewer Cases of Possible Breast Cancer Precursor

November 12, 2009
As hormone use declined, so did incidence of abnormal cells in milk ducts, study finds. Declining use of hormone replacement therapy may be driving down rates of a condition called "atypical ductal hyperplasia," a known risk factor for breast cancer, new research suggests.

This is the first time a link has been found between atypical ductal hyperplasia .

Leukemia Drug May Help Some Ovarian Cancer Patients

November 12, 2009
Sprycel limited the growth of cancer cells in lab study. A drug for people with a form of leukemia holds promise as a possible treatment for ovarian cancer, new research suggests.

The drug dasatinib (Sprycel) is used to treat chronic myeloid leukemia. Researchers at the University of California at Los Angeles report that the drug limited the growth and invasive powers of ovarian cancer cells.

My 10-Day Ordeal With the Swine Flu

November 12, 2009
Reporter recounts her bout with H1N1, made all the worse by chronic asthma. Like most people, I've been following the news about the H1N1 swine flu with some concern. Unlike most people, however, I've spent years interviewing doctors.

And from the many hours talking with infectious-disease specialists, I knew that it was never a matter of if there might be another flu pandemic, but when.

Older People at Greater Risk of Swine Flu Death

November 12, 2009
Cases in Mexico show young more likely to get sick, but elderly more likely to die. A study of H1N1 swine flu in Mexico finds that while babies and people under the age of 40 are most likely to get sick, elderly people have the highest death rates.

The research, published online Nov. 11 in The Lancet, analyzed medical records of patients at clinics in the Mexican Institute for Social Security network, who became sick with flu-like illnesses between April 28 and July 31, 2009.

Tamiflu-Resistant Swine Flu Found in Canadian Father

November 11, 2009
Latest case underscores need to use the antiviral properly, experts say. Researchers report that a father in a Canadian family developed a strain of the H1N1 swine flu that was resistant to the antiviral Tamiflu, after being given the drug to prevent the disease.

To date, the World Health Organization has reported some 45 cases of H1N1 swine flu that were resistant to Tamiflu, which is why the U.S.

Trial Data on Anti-Seizure Drug Might Have Been Manipulated

Report

November 11, 2009
Study found outcome measures differed between company documents, published reports. An unusual look at internal documents from a pharmaceutical company suggests that clinical data was manipulated to make a popular anti-seizure drug, gabapentin (Neurontin), look more effective than it actually was, thereby increasing possibilities for its off-label usage, according to a new report.

"This means we're not seeing the full picture, and the picture we are seeing is suspect because perhaps there was selective reporting of outcomes so that only the positive outcomes were reported," said Kay Dickersin, senior author of a paper reporting the alleged deception in the Nov. 12 issue of the New England Journal of Medicine.

Cancer Can Strain Marriages to Breaking Point

November 11, 2009
But men much more likely to leave than women if spouse is sick, study finds. Cancer can put an enormous strain on a marriage, and couples are much more likely to fall apart if the woman is the patient.

In fact, the odds of separation or divorce are six times higher compared to when the man is the one with the illness, a new study shows.

The researchers did find that couples that have been married longer are more likely to survive the difficulties of dealing with cancer.

Gut Bacteria Might Be Making People Fat

November 11, 2009
Study in mice suggests link between intestinal microbes, diet and obesity. Eating a Westernized diet with lots of sugar and carbohydrates caused almost instantaneous changes in the gut flora of mice .

BPA Tied to Impotence in Men

November 11, 2009
Chinese factory worker study suggests more potential hazards from the plastics chemical. Exposure to high levels of the controversial plastics chemical bisphenol A (BPA) significantly raised the risk of sexual dysfunction, including impotence and low sex drive, among Chinese factory workers, a new study has found.

The researchers stressed that the workers were exposed to BPA levels about 50 times higher than what most Chinese or Americans would be exposed to in everyday life.

Even so, they said the study adds to a growing body of research that shows that the ubiquitous chemical may be harmful to humans.

New Polyp Detection Method Could Be Cost-Saver

November 11, 2009
Optical technology is as accurate as colorectal tissue examination, study finds. Optical technology could help physicians detect small colorectal polyps during colonoscopies and save money, too, new research suggests.

In the report, published online Nov. 10 in The Lancet Oncology, the study authors explained that the technique could replace histopathology, which requires more testing and can be costly.

Anemia Drugs May Cause Deadly Blood Clots

November 10, 2009
Study raises more concerns about common treatment for chemo patients. New research on cancer patients adds to the controversy surrounding anemia drugs such as Procrit and Aranesp, concluding that they increase the risk of venous thromboembolism, potentially fatal blood clots.

These drugs, called erythropoiesis-stimulating agents (ESAs), are commonly prescribed to fight anemia associated with chemotherapy and chronic kidney disease. Recent studies have linked them with increased risk of death, stroke and new cancers.

Breast Cancer May Be Gone, But Pain Lingers

November 10, 2009
Nearly half of patients have chronic pain, researchers find. Even three years after finishing treatment for breast cancer, almost 50 percent of women report long-term pain, a new Danish study finds.

The research, published in the Nov. 11 issue of the Journal of the American Medical Association, strengthens earlier findings, said study senior author Dr.

Muscle Weakness Linked to Alzheimer's Risk in Seniors

November 10, 2009
Reason for association unknown, but stroke is one possibility, researchers say. Elderly people with weak muscles may be at increased risk for Alzheimer's disease, according to a new study.

Researchers at Rush University Medical Center in Chicago followed 970 older adults (average age 80) who didn't have dementia at the start of the study. The participants underwent a number of evaluations, including tests of cognitive function and muscle strength.

Teen Obesity Ups MS Risk in Women

November 10, 2009
Researchers suspect lower vitamin D levels may be to blame. While there are plenty of good reasons to avoid obesity in your teens, a new study now suggests that extra weight in adolescence may increase your risk of multiple sclerosis (MS) later.

Reporting in the Nov. 10 issue of Neurology, Harvard researchers found that being obese at age 18 more than doubles a woman's risk of developing MS later in life compared to her slimmer peers.

Early Use of NSAIDs Might Prevent Alzheimer's

November 10, 2009
Study in mice finds anti-inflammatories don't help those with existing disease. Taking nonsteroidal anti-inflammatory drugs (NSAIDs) from a young age might prevent early signs of Alzheimer's disease, according to the results of a new study in mice.

Recent research suggests that the appearance of neuronal cell cycle events (CCEs) occurs early in the development of Alzheimer's. In the new study, U.

Breast Cancer Drugs May Fight Cervical Cancer, Too

November 09, 2009
Study in mice reports success with drugs that inhibit estrogen. Two drugs used to treat breast cancer and osteoporosis eliminated cervical cancer in mice, according to a new study.

The drugs also cleared precancerous growths in the cervix and vagina, and prevented the onset of cancer in mice with precancerous lesions.

The breast cancer drug fulvestrant and the breast cancer/osteoporosis drug raloxifene were given to mice genetically engineered to carry human papillomavirus (HPV) 16, which is strongly associated with cervical cancer.

To Feel Better, Low-Fat Diet May Be Best

November 09, 2009
Comparison of plans finds differences in mood despite similar weight loss. Both a high-fat, low-carbohydrate diet such as the popular Atkins program and a low-fat, high-carb diet appear to help people lose pounds over the course of a year.

But as for mood? Only the low-fat diets will result in long-term improvement in mood, according to a study in the Nov. 9 issue of Archives of Internal Medicine.

Cataract Surgery Doesn't Worsen Macular Degeneration

Study

November 09, 2009
Link likely due to fact that both eye conditions are age-related, researchers say. Cataract surgery doesn't appear to speed the progression of age-related macular degeneration (AMD), according to a new study that challenges the belief that treating one cause of vision loss worsens the other.

"Because both conditions are strongly age-related, many individuals with cataract also have AMD," wrote Li Ming Dong, of Stony Brook University School of Medicine in New York, and colleagues. "There has been a long-standing controversy among clinicians as to whether cataract surgery is contraindicated in eyes with non-neovascular AMD.

Dense Breasts Raise Risk of Cancer Recurrence

November 09, 2009
Study didn't answer question of why this is so, however. After a lumpectomy, women with very dense breasts have a higher risk of cancer recurrence in the affected breast, a new study shows.

Breast density has already been linked with an increased risk of developing breast cancer, and experts have suspected that very dense breasts may also be associated with an increased risk of cancer recurrence at the site of the original cancer after lumpectomy.

The Canadian study, which involved a 10-year follow-up and is published online Nov.

Depressed and Pregnant? Flu Shot May Be Needed

November 09, 2009
Symptoms of seasonal flu could be severe in this group of women, study finds. Pregnant women who are depressed may suffer severe symptoms if they catch seasonal flu, a new study suggests.

Ohio State University researchers assessed depressive symptoms and took blood samples from 22 pregnant women before they received a seasonal flu shot. Those with significant symptoms of depression had a stronger inflammatory response to the flu shot than the other women.

Most Who Want Swine Flu Shot Can't Get It

November 06, 2009
CDC says 38 million doses now available, with 8 million more due next week. Although the total doses of H1N1 swine flu vaccine available in the United States now tops 38 million .

Stem Cells May Offer Alternative to Lung Transplants

November 06, 2009
Novel protocol could provide new lung tissue for certain patients, researchers say. Belgian scientists who used embryonic stem cells to create lung tissue say this technique could provide an alternative to lung transplants for patients with chronic obstructive pulmonary disease (COPD) and cystic fibrosis.

This is the first time it's been shown that embryonic stem cells can be converted into airway epithelial-like cells without the use of specific growth factors or embryoid body formation. The researchers achieved this using an "air-liquid interface" system that mimics the conditions found in an adult trachea.

Early Relapse of MS May Mean Fewer Issues Later

November 06, 2009
Short-term limitations seem to wane as years go by, researcher says. New research suggests that people with multiple sclerosis who have relapses within five years of developing the disease are more likely to suffer from severe limitations in the short term than others with the condition.

The findings, published Nov. 4 in Neurology, show that people with the disease who relapse within five years of developing it are nearly 50 percent more likely to need a cane to walk during that time period.

Istodax Approved for Cutaneous T-Cell Lymphoma

November 06, 2009
It's a disfiguring cancer affecting the skin The Gloucester Pharmaceuticals drug Istodax (romidepsin) has been approved by the U.S. Food and Drug Administration to treat cutaneous T-cell lymphoma (CTCL) in people who have tried at least one prior systemic therapy, the drug's manufacturer said in a news release.

New Smells 'Etched' in Brain

Study

November 06, 2009
Findings might play a role in boosting memories -- or forgetting them, researchers say. Do you remember the first time you smelled a type of flower? You almost certainly don't, but new research suggests that your brain might.

In the study, published online Nov. 5 in the journal Current Biology, researchers showed objects to adult study participants.

Thyroid Cancer Higher in Volcanic Areas

November 06, 2009
Study finds exposure to toxic compounds may explain the increased cases. New research suggests that living near a volcano puts people at higher risk of getting a type of thyroid cancer.

It's not clear how volcanoes might be related to cancer, but researchers suspect that the toxic compounds they produce could play a role.

Researchers are also unsure of why thyroid cancer rates are rising around the world.

Health Fears Are Nothing to Sneeze At

November 06, 2009
After witnessing a sneeze, people worry more about flu, heart attacks, accidents and crime, study finds. It may sound hard to believe, but just one sneeze is enough to increase your fear not just of contracting flu, but also of dying from a heart attack at an early age, dying from an accident or being the victim of a fatal crime, new research shows.

Of greater concern, however, was that people who'd just been exposed to a sneezing actor were three times as likely to want to spend $1.3 billion on the development of a flu vaccine instead of creating jobs in "green" industries than those who hadn't been near someone sneezing.

Early Morning Colonoscopies May Find More Polyps

November 06, 2009
Study suggests differences in patient preparation and doctor fatigue play a role. Early morning colonoscopies detect more polyps than colon cancer screenings done later in the day, and the number of polyps found decreases by the hour as the day progresses, a new study has found.

Removing polyps is believed to reduce the risk of colon cancer by 60 to 90 percent.

Researchers from the University of California, Los Angeles, analyzed data on 477 people who had colonoscopies in a one-year span at a Veterans Affairs hospital.

Cooling May Reduce Brain Lesions in Newborns

November 06, 2009
Treatment after oxygen deprivation accounts for better motor skills later, study suggests. Babies who are deprived of oxygen at birth often go on to have lifetime disabilities, but research has shown that cooling infants can help prevent problems.

Now, a new study reports that the cooling actually reduces the number of brain lesions in the babies.

Oxygen starvation at birth can cause a condition called hypoxic-ischemic encephalopathy, which can be fatal.

Firm Says Low-Cost Genome Sequencing Is Possible

November 05, 2009
10,000 human genomes could be sequenced next year, company says. A genome sequencing company says it has developed a lower-cost DNA platforming sequence.

Its report, including an analysis of data from three full human genomes, was published Nov. 5 in Science.

Swine Flu Virus Dominant Strain Worldwide

WHO

November 05, 2009
Agency says pathogen continues to target younger adults, producing mild-to-moderate illness. The H1N1 swine flu virus is now the predominant flu strain worldwide, although it shows no signs of becoming more virulent and continues to produce mild-to-moderate symptoms in most people, the World Health Organization's flu chief said Thursday.

In some countries, the swine flu accounts for up to 70 percent of the flu viruses being sampled, Dr. Keiji Fukuda said during a press briefing, the Associated Press reported.

Green Tea May Help Prevent Oral Cancer

November 05, 2009
Small study reports evidence of cancer-fighting properties. A new study appears to add to growing evidence that green tea might help protect against cancer.

U.S.

Health Tip

Triggering Abdominal Bloating

November 05, 2009
Some typical causes When your belly feels bloated, uncomfortably tight and full, your doctor may refer to it as abdominal bloating.

The U.S.

Rest Easy. When It Comes to Swine Flu, Your Pet Is Safe

November 05, 2009
Recent reports of H1N1 in a cat or pigs are likely very rare, experts say. When the news broke on Wednesday that a domestic cat had come down with H1N1 swine flu, probably transmitted to the feline by sick owners, many people no doubt wondered how vulnerable their own pets were to the illness.

So, does Fluffy or Fido need protecting from this strain of flu? The answer, experts say, is basically no.

While the H1N1 flu currently circulating can jump easily from person to person, it does not travel well from humans to animals or animals to humans, except in a few rare instances.

New HPV Vaccine Might Stop Vulvar Cancer in its Tracks

November 04, 2009
Working differently than Gardasil, Cervarix, it targets inside of virus, study shows. A vaccine that targets human papillomavirus (HPV) is able to stop precancerous lesions in the vulva from progressing into full-blown malignancies, Dutch researchers report.

Two other vaccines .

Will New Anemia Drug Top Current Treatments?

November 04, 2009
Designed for a rare condition, it might have a wider application, experts say. A new drug designed to treat patients with a rare form of anemia could possibly have wider applications, perhaps replacing other anemia treatments that have been linked to an increased risk of death, cancer and stroke, experts say.

The drug, Hematide, was successful in treating patients who have pure red-cell aplasia, a condition caused by antibodies to a hormone needed to produce red blood cells. It's a "devastating condition that many patients have died from and ties patients to blood transfusions every two weeks for the rest of their life," said lead researcher Dr.

FDA Initiative Seeks to Reduce Accidental Overdoses

November 04, 2009
The program will enlist health-care workers, drug makers, consumers, patients. U.S. health authorities unveiled Wednesday an initiative designed to reduce preventable injuries and deaths caused by misuse of medications.

PSA Reading Could Predict Post-Radiation Survival

November 04, 2009
Rising level in prostate cancer patients may call for more treatment, study finds. Prostate cancer patients whose prostate-specific antigen (PSA) levels rise within 18 months after radiotherapy have an increased risk of death, say U.S. researchers.

Waiting, Wondering About Radiology Results Irks Patients

November 04, 2009
Getting details in writing would be ideal, survey finds. Many patients don't like how long it takes to receive the results of radiology tests and aren't happy with the lack of information when they do get the results, a U.S. study has found.

Shorter, More Intense Radiation OK for Some Breast Cancers

November 04, 2009
Three-week course comparable to six-week treatment, researchers find. A shorter, more intense course of whole-breast radiation works as well as the traditional six-week course, at least for some early-stage breast cancers, a new study shows.

"This concept of a shorter length of treatment is gaining acceptance," said Dr. Manjeet Chadha, associate chair of radiation oncology at Beth Israel Medical Center and associate professor of radiation oncology at Albert Einstein College of Medicine, both in New York City.

Focused Radiation May Help Some With Lung Cancer

November 04, 2009
Study reports successes, especially for those with good lung function. Three-year survival was 100 percent for people with early-stage lung cancer and good lung function who were treated with radical stereotactic radiosurgery using CyberKnife, according to a new study funded by the product's maker.

Standard care for people with small lung tumors calls for surgical removal of the affected lobe, but some people cannot have surgery because of other medical conditions, such as heart disease or emphysema.

"Our goal has been to find a reasonable option for patients who don't want or can't tolerate surgery," the study's lead author, Dr.

CDC Urges Patience As More Swine Flu Shots Arrive

November 03, 2009
Total should near 42 million by week's end; more health-care workers getting vaccine. The United States has 31.8 million H1N1 flu vaccine doses available and is on track to have another 10 million ready by week's end, a federal health official said Tuesday.

So far, that isn't enough to prevent long lines at vaccination centers, but it is consistent with what officials had projected earlier this week.

Low Cholesterol May Help Prevent Cancer

November 03, 2009
Two studies dispel longstanding fears about possible connection. Low blood cholesterol levels reduce the risk not only of heart disease but also of cancer, two new studies show.

The findings should help ease longstanding fears that low cholesterol is associated with an increased risk of cancer, said Dr. Demetrius Albanes, a senior investigator at the U.

Severe Swine Flu Can Kill Young, Old Alike

November 03, 2009
Seniors may carry some immunity, but more likely to die if hospitalized, study finds. Californians both young and old are contracting H1N1, with infants the most likely to be hospitalized and adults over the age of 50, once hospitalized, the most likely to die, a new study shows.

The report, appearing in the Nov. 4 issue of the Journal of the American Medical Association, somewhat contradicts the popularly held notion that elderly people are relatively immune from the ravages of this new infection.

FDA Issues Warning for Diabetes Drug

November 03, 2009
Reports of kidney problems for those using Byetta prompted action. Reports about possible kidney problems, including renal failure, in people taking the diabetes drug exenatide (Byetta) have prompted changes to the drug's prescribing information, the U.S. Food and Drug Administration said Monday.

Drug Could Help Treat Small HER2-Positive Breast Tumors

November 03, 2009
Researcher urges studies to determine benefits of anti-HER2 therapies. Women with a relatively uncommon type of breast cancer are significantly more likely to face its recurrence and spread, but researchers now say these women may benefit from treatment with the breast cancer drug Herceptin.

Two studies, from the United States and Italy, examined cases of women with small (1 centimeter or less in diameter) HER2-positive breast cancers that hadn't spread to the lymph nodes. The researchers found that the cancer is more than two times more likely to recur in HER2-positive women than in women with HER2-negative breast cancers.

CDC Finds U.S. 30th in Infant Mortality

November 03, 2009
Finding is attributed to country's high rate of premature births. When comparing rates of infant mortality, the United States lags dismally behind most other developed countries, largely because of a disproportionately high number of babies delivered prematurely, according to a new government report.

"The U.S.

Switch to 'Light' Cigarettes Makes Quitting Tougher

November 03, 2009
Smokers may mistakenly believe they're 'healthier,' researchers say. Experts have long known that "low-tar" and "light" cigarettes aren't any healthier than regular cigarettes, and new research suggests they have another drawback: People who switch to them are less likely to quit, even those who switch specifically because they want to stop smoking.

In fact, "switching to ['light' cigarettes] for any reason is associated with continuing to smoke," said study author Dr. Hilary Tindle, a researcher at the University of Pittsburgh's Division of General Internal Medicine.

One Dose of Swine Flu Vaccine Works for Pregnant Women

November 02, 2009
Young children need two doses, spaced several weeks apart, U.S. health officials say. Results from ongoing clinical trials confirm that pregnant women need only one dose of the swine flu vaccine, while young children .

Doctors Overprescribing the Pap Test

November 02, 2009
Many ignore guidelines and recommend screening to women at low risk for cervical cancer, survey shows In 2002 and 2003, screening guidelines for the cervical cancer-detecting Pap test were changed significantly, yet fewer than one-third of U.S. primary care physicians follow those guidelines, according to a recent study.

Radiation After Surgery Lowers Chances of Melanoma Recurrence

November 02, 2009
But study did not find effect on overall survival. Patients whose melanoma has spread to one or more lymph nodes face a decreased risk of the deadly skin cancer returning if they have radiation treatment following the removal of the nodes, a new Australian study shows.

In a paper to be presented Monday at the American Society for Radiation Oncology annual meeting in Chicago, lead researcher Dr. Bryan Burmeister, a radiation oncologist at Princess Alexandra Hospital in Brisbane, reported the hopeful findings from the five-year study.

Hormone Therapy Can Help Some With Prostate Cancer

November 02, 2009
But often not needed for early-stage patients, long-running study shows A brief course of hormone-blocking therapy can provide small benefits to a specific group of men who get radiation therapy for prostate cancer, a long-running study shows.

Ten-year survival was 62 percent in men with cancers graded as intermediate risk who got treatment that blocked their male hormone activity in addition to radiation therapy, compared to 57 percent of those who got radiation therapy alone, said Dr. Christopher U.

Restless Legs May Vary by Race and Gender

November 02, 2009
Blacks are less likely, women more, to develop the disorder, study finds. Restless legs syndrome, a neurological disorder characterized by a strong urge to move the legs, is much more common among some racial groups than others, a new U.S. study has found.

Delays in Lung Cancer Care More Common in Public Hospitals

November 02, 2009
Age, race, insurance also influence timing between diagnosis and therapy, study finds. The length of time a patient has to wait between lung cancer diagnosis and treatment is influenced by a number of health-care system factors, a new U.S. study finds.

Health Tip

Getting a Pap Test

November 02, 2009
Who needs one and when A Pap test (Pap smear) collects a sample of cells from the cervix to look for any abnormalities or changes. It's often used to help diagnose infections or cervical cancer.

The National Women's Health Information Center offers these guidelines for whom should have a Pap test, and how often:


Women younger than age 30 should get an annual Pap test.

Childhood Brain Cancer Causes Other Long-Term Problems

November 02, 2009
Treatment leaves survivors with significant cognitive decline, researchers find. Childhood brain cancer survivors have ongoing cognitive problems and achieve lower levels of education, employment and income than their siblings and survivors of other types of cancer, a U.S. study has found.

Five-Minute Survey Can Help Predict Lung Cancer

November 02, 2009
Office visit questionnaire led to screening in high-risk study patients. A simple questionnaire can identify patients at high risk for lung cancer, researchers say.

In a study that began in 2001 with 1,000 people in Colorado who were seeing their primary care physician for general health issues, patients were asked to complete a five-minute questionnaire that collected information about lung cancer risk factors, including smoking, family history, exposure to chemicals and work environments.

Based on their responses, 430 patients were considered to be at high risk for lung cancer.

Anemia Drug May Raise Stroke Risk in Kidney Patients

November 02, 2009
Use of Aranesp should be reserved for the most seriously ill, experts say. A drug designed to fight anemia appears to double the risk of stroke in patients with diabetes and kidney disease without substantially improving their quality of life, a new study finds.

Darbepoetin alfa, marketed as Aranesp and known as an erythropoiesis-stimulating agent (ESA), is often prescribed for diabetic patients with chronic kidney disease and mild anemia.

"The benefits we assumed we would have by treating anemia were less striking and the risks were more striking," said lead researcher Dr.

Flu Deaths Higher Among Seniors With Dementia

October 30, 2009
Study suggests mortality rate may be linked to health-care inadequacies. Seniors with dementia are diagnosed with flu less often, have shorter hospital stays and are 50 percent more likely to die than those without dementia, says a U.S. study that looked at flu and pneumonia in adults 65 and older.

At Least 114 U.S. Kids Dead From Swine Flu

October 30, 2009
Two-thirds had chronic health problems, CDC says. At least 114 U.S. children have now died from laboratory-confirmed H1N1 swine flu, including 19 during the past week .

Patients More Likely to Die While in ICU in U.S. Than in England

October 30, 2009
More study needed to discern if difference is due to intensive care overuse or underuse Dying hospital patients in the United States are nearly five times more likely to spend their last days in the intensive care unit than patients in England, finds a new study, and U.S. patients over age 85 are eight times more likely to be in the ICU when they die.

Asians Seem to Suffer Less During Childbirth

October 30, 2009
Length of labor and intensity vary among ethnic groups, study finds. Asian women experience less labor pain than other women, say U.S. researchers.

Undocumented Hispanics Face Health Care Roadblocks in U.S.

October 30, 2009
Policies needed to eliminate disparities among immigrants, survey findings suggest. Financial and language issues pose serious barriers to quality health care for undocumented foreign-born Hispanics in the United States, say researchers who called for improved health systems for all immigrants.

The study authors analyzed data from the 2007 Pew Hispanic Center/Robert Wood Johnson Foundation Latino Health Survey of more than 4,000 Hispanic adults across the United States. The researchers examined differences in perceived quality of care, receipt of preventive care, and usual source of health care among foreign-born, U.

Flu Shot in Pregnancy Protects Baby

October 30, 2009
Vaccinating expectant moms led to bigger, healthier infants, studies show. Pregnant women head the list of people who should get H1N1 swine flu and seasonal flu shots, and four new studies highlight the benefits of vaccination for moms-to-be and their babies.

Bigger, healthier newborns, fewer preterm births and reduced rates of hospitalization top the findings, which are to be presented this week at the annual meeting of the Infectious Disease Society of America in Philadelphia.

In one study, U.

Almost 6 Million U.S. Cases of Swine Flu in First Few Months

October 29, 2009
CDC says H1N1 may be tied to 21,000 hospitalizations during that time. Up to 5.7 million cases of H1N1 swine flu hit the United States between April and July, according to a new estimate from the U.S.

Tamiflu-Resistant Swine Flu Passed Person-to-Person in U.S.

October 29, 2009
Another study shows kids shed virus up to 13 days after fever starts. U.S. researchers say they've spotted the first case of a Tamiflu-resistant H1N1 flu virus passing between two people .

Rheumatoid Arthritis Treatment Doesn't Promote Cancer

October 29, 2009
No added risk among patients taking immunosuppressants, research shows. Treatment with tumor necrosis factor (TNF) blockers doesn't increase rheumatoid arthritis patients' risk of cancer, new research has found.

TNF is a substance secreted by immune cells that regulates the immune system and plays a role in inflammation. TNF blockers are immunosuppressants that reduce inflammation in people with rheumatoid arthritis, but concerns have been raised that long-term use of the drugs may increase the risk of infections and cancer.

Cholesterol Drugs May Help Prevent Flu Deaths

October 29, 2009
But expert says it could be that statins protect heart during infection. Statins, frequently used to cut cholesterol levels, may also help prevent death from severe flu, a new study suggests.

According to the researchers, a growing body of evidence suggests that statins .

Health Tip

Screening for Cancer

October 29, 2009
A list of available tests

The best way to get a good prognosis when it comes to cancer is to get diagnosed as early as possible .

1 Million More Doses of Swine Flu Vaccine on Hand

October 28, 2009
Gap between supply and demand starting to close, U.S. officials say. U.S. officials reported Wednesday the addition of another million doses H1N1 swine flu vaccine, bringing the total so far to 23.

Testicular Cancer Survivors Face Other Ills

October 28, 2009
Treatment can cause long-term neurological, circulatory problems, study finds. For men with testicular cancer, survival comes at a price: New research suggests that those who recover from the disease face higher risks of long-term illness unrelated to tumors.

"Current patients with testicular cancer should be informed about the risk of short-term and particularly long-term side effects of their highly effective treatment," said Sophie D. Fossa, a professor at the University of Oslo in Norway and lead author of a study in the November issue of the journal BJUI.

Meditation May Reduce Stress in Breast Cancer Patients

October 28, 2009
Women report improved emotional and mental health in study. Transcendental meditation reduces stress and improves the emotional and mental well-being of breast cancer patients, new study findings suggest.

The two-year trial included 130 patients at Saint Joseph Hospital in Chicago, aged 55 and older, randomly assigned to either a transcendental meditation group or to a usual care control group. Quality of life was assessed every six months.

Adding Chemo Helps Head, Neck Cancer Patients

October 28, 2009
Study found it doubled survival time. Combining chemotherapy with radiation treatment for patients with advanced head and neck cancer increases their event-free survival to 2.2 years from just one year with radiotherapy alone, finds a new study.

According to the study authors, "events" include cancer recurrence, new tumors or death.

More Swine Flu Vaccine Coming Soon

October 27, 2009
22 million doses out now, and shortage should ease over coming weeks, CDC says. The H1N1 swine flu is spreading throughout the United States and vaccine remains in short supply, but federal health officials said Tuesday that more than 22 million doses are now available, with more expected in coming weeks.

"This is a challenging time," Dr. Thomas R.

Old, New Pap Methods Equally Good, Dutch Study Finds

October 27, 2009
But U.S. expert predicts 'major change' in testing methods in a few years. Traditional Pap tests and the newer liquid-based cytology are equally reliable in screening for cervical cancer, a new study has found.

In the United States, liquid-based cytology testing has all but replaced the traditional Pap test, but in Europe the debate continues over which method is best, according to Dr. Mark Schiffman, a senior investigator at the U.

Mapping the Link Between Alcohol, Cancer

October 27, 2009
How it affects tumor cells is becoming less of a mystery, study finds. New research suggests that alcohol may boost the progression of cancer by stimulating a pathway inside cells.

The findings could have meaning for the prevention and treatment of cancer, which has been linked to alcohol use in some cases. In particular, scientists suspect that alcohol is connected to colon and breast cancer, although it's not known exactly how.

Arzerra Approved for Chronic Lymphocytic Leukemia

October 27, 2009
Affects some 16,000 people annually Arzerra (ofatumumab) has been approved by the U.S. Food and Drug Administration to treat chronic lymphocytic leukemia (CLL), a cancer of the blood and bone marrow.

Radiation From Medical Scans Soaring

October 27, 2009
Americans now get 6-fold more exposure than in 1980, researchers say. Americans' exposure to radiation from medical procedures has exploded over the past few decades, to six times the level of 1980, a new report shows.

In 2006, almost 380 million diagnostic and interventional radiological procedures were performed in the United States, on top of 18 million nuclear medicine examinations.

"Back in about 1980, 15 percent of radiation that the U.

Exposure to Holocaust May Have Raised Cancer Risks

October 26, 2009
Survivors offer clues to the impact of severe physical, psychosocial suffering, researchers say. Among Jewish survivors of World War II, those who were potentially exposed to the Holocaust have an increased risk of cancer, likely due to physical and mental stress, an Israeli study has found.

University of Haifa researchers compared cancer rates in more than 300,000 Israeli Jews who were born in Europe and immigrated to Israel either before World War II (non-exposed) or after the war (potentially exposed).

Compared to the non-exposed group, those in the potentially exposed group had a statistically significantly increased risk for cancer, especially breast and colorectal cancer, the researchers found.

Sebelius

There Will Be Swine Flu Vaccine for All Who Want It

October 26, 2009
But the HHS secretary admits that delays are limiting supplies so far. While acknowledging delays in getting the swine flu vaccine to Americans, U.S. Health and Human Services Secretary Kathleen Sebelius said Monday that the vaccine "is coming out the door as fast as it comes off the production line.

Bowel Disease Treatment May Raise Skin Cancer Risk

October 26, 2009
Rates of non-melanoma cancer higher in patients with Crohn's, ulcerative colitis, study finds. Inflammatory bowel disease (IBD) patients who are being treated with immunosuppressive medications may be at increased risk for non-melanoma skin cancer, a new U.S. study says.

Breast Abnormality Follow-Up Often Later in Black Women

October 26, 2009
Reasons for delay are unclear, researchers say. Black women experience a significant delay in follow-up after discovery of a breast abnormality, a U.S. study has found.

Blacks at Greater Risk for Colorectal Cancer

October 26, 2009
Race seems to play pivotal role, researchers say.
New research finds that blacks are at much higher risk of developing colorectal cancer than other groups of people, and they are more likely to be diagnosed at a later stage of the disease.

Researchers from the California Pacific Medical Center examined medical records regarding more than a half million cases of colorectal cancer that were diagnosed from 1973 to 2004.

They were scheduled to present their findings Monday at the American College of Gastroenterology annual meeting in San Diego.

Sperm May Play Role in Transmission of HIV

October 26, 2009
Semen isn't the only way men spread virus during sex, new research shows. New research suggests that sperm, not just semen, can transmit the virus that causes AIDS to immune cells in the body and, in fact, sperm may play a major role in transmission.

Scientists already know that men infected with HIV, the virus that causes AIDS, can spread the disease through their semen, the fluid that carries sperm. But it hasn't been clear what role sperm itself plays, especially considering that men who don't produce sperm, such as those who have had vasectomies, can transmit the virus.

Is Smoking Tougher on Women?

October 25, 2009
Research suggests they're more susceptible to dangers of tobacco. Women may be more vulnerable than men to the carcinogens and other noxious substances in cigarette smoke, a growing body of research suggests.

In one study of nearly 700 people with lung cancer, Swiss experts found that women tended to be younger when they received the diagnosis, even though they smoked less than the men who developed lung cancer.

In another study, researchers from Harvard University and the University of Bergen in Norway evaluated more than 950 men and women with chronic obstructive pulmonary disease (COPD), known to be linked to smoking.

Obama Declares Swine Flu a National Emergency

October 25, 2009
Action allows hospitals to better handle large numbers of patients as outbreak spreads President Barack Obama has declared the H1N1 swine flu a national emergency.

His proclamation, signed Friday night and released by the White House Saturday, will allow hospitals and doctors' offices to get legal waivers of federal rules so they can handle large numbers of sick people as the outbreak spreads.

"The H1N1 is moving rapidly, as expected.

HPV Vaccine No More Painful Than Other Shots

October 23, 2009
Reports that injection sting is excessive disputed in U.S. study. There have been reports that injections of the human papillomavirus (HPV) vaccine are especially painful, but a new study finds that they don't hurt more than any other shots.

Public health officials worried that reports of excess pain might prevent young women from getting the vaccine, which protects against a virus that can cause cervical cancer, some other kinds of cancer and genital warts. There was also concern that some women might not get all three required doses.

Swine Flu Vaccine Still in Short Supply

October 23, 2009
Goal of 40 million doses by end of October won't be met, CDC says. Production delays continue to hamper distribution of the H1N1 swine flu vaccine, a leading U.S. health official said Friday.

Light Touch Helps Grip of MS Patients

October 23, 2009
Study shows ways to optimize hand movements. Using a gentle touch may help make it easier for people with multiple sclerosis to pick up and hold objects, a new study suggests.

People with MS use excessive force when lifting objects, which can lead to fatigue and make everyday tasks difficult, physical therapists from the University of Illinois at Chicago explained in a school news release.

Using the finger of the opposite hand to apply a gentle touch to the affected hand may help improve control and coordination, they stated.

Coffee May Slow Liver Disease

October 23, 2009
Finding could be good news for those with hepatitis C, researchers say. Coffee slows the progression of advanced liver disease in people with chronic hepatitis C, new research finds.

The study included 766 patients infected with hepatitis C virus (HCV) who were asked to report their intake of coffee, green tea and black tea. The patients were seen every three months during the nearly four-year study, and liver biopsies were taken at 18 months and 3.

Babies Spot Human Speech at 5 Months

October 23, 2009
They easily distinguish language from animal sounds, researchers say. Children as young as 5 months old are able to tell the difference between human speech and monkey calls, a new study has found.

Researchers showed 5-month-old infants from English- and French-speaking homes pictures of human faces and rhesus monkey faces paired with either human speech or monkey calls. The infants looked longer at pictures of human faces when human speech was presented and longer at monkey faces when monkey calls were played.

Production Problems Plague Delivery of Swine Flu Vaccine

October 23, 2009
Despite significant shortfall, CDC says all Americans who want shot will be able to get one, eventually. As reports of swine flu infections continue to pour in from across the United States, health experts labored Thursday to explain why delivery of stocks of the long-awaited H1N1 vaccine are falling behind schedule.

Federal officials had projected that 40 million doses would be on hand by Oct. 15, but not even 13 million doses had arrived by Tuesday.

Dying Wishes Followed More Often for Whites

October 22, 2009
Better communication needed for black patients, researchers say. Dying white cancer patients are more likely than black patients to have their end-of-life wishes respected, a new U.S. study shows.

Guidelines Urge Use of Erectile Dysfunction Drugs

October 22, 2009
Which product to prescribe depends on patient preferences, experts say. Doctors should prescribe oral phosphodiesterase type 5 (PDE-5) inhibitor drugs, such as Viagra, Cialis and Levitra, for men with erectile dysfunction, unless the patient is on nitrate therapy, according to a clinical practice guideline issued by the American College of Physicians.

The type of erectile dysfunction (ED) drug prescribed should be based on the individual preferences of patients, including cost of medication, ease of use and types of side effects, the authors noted.

"The evidence is insufficient to compare the effectiveness or adverse effects of different PDE-5 inhibitors for the treatment of ED because there were only a few head-to-head trials," guideline lead author Dr.

Some Parts of Human Genome Get Lost

October 22, 2009
Technology allows scientists to spot non-essential DNA base pairs. Researchers have created their first map of parts of the human genome that are considered disposable.

Scientists estimate that at least 2.7 million base pairs of the human genome, which reside in 58 distinct regions of DNA, are non-essential and can disappear without hurting people's health.

Drug Use in Teens May Damage Memory Years Later

October 22, 2009
Young rats given amphetamines suffered short-term losses as adults, study finds. Rats develop memory loss in adulthood after receiving high doses of amphetamines during their "teen" years, new research shows.

Exposure to the drugs during adolescence has a more severe impact on short-term memory than being exposed as adults, researchers found in a study that was to be presented this week at the Society for Neuroscience annual meeting, in Chicago.

"Animals that were given the amphetamine during the adolescent time period were worse at tasks requiring working memory than adult animals that were given the same amount of amphetamine as adults," study co-author and psychology professor Joshua Gulley of the University of Illinois at Urbana-Champaign, said in a school news release.

Study Finds Less Toxic Treatment for Myeloma

October 22, 2009
Lower dose of standard medication leads to better outcome, researchers say. Cancer researchers say they have a better treatment for patients with newly diagnosed multiple myeloma than the current standard therapy.

Their study finds that treatment with lenalidomide plus low-dose dexamethasone is associated with better short-term survival and with lower toxicity than lenalidomide plus high-dose dexamethasone, which is the mainstay of therapy for the bone marrow cancer.

The study included more than 400 patients with untreated, symptomatic myeloma who received lenalidomide (25 milligrams for 21 days) plus a high dose of dexamethasone (40 milligrams on days one to four, nine to 12, and 17 to 20 of a 28-day cycle), or who received lenalidomide on the same schedule with a low dose of dexamethasone (40 milligrams on days one, eight, 15 and 22 of a 28-day cycle).

CT Scans Surpass X-Rays for Swine Flu

Study

October 22, 2009
In high-risk patients, scans better able to spot serious complications, researchers say. New research suggests that computed tomography (CT) scans are better than standard X-rays at detecting the severity of illness in patients with the H1N1 virus, known as swine flu.

Researchers examined seven patients infected with the virus and gave chest X-rays to all of them. Three of the patients also received CT scans.

Swine Flu Parties? Send Your Regrets, Experts Say

October 22, 2009
Some parents reportedly exposing healthy kids to those already sick with the H1N1 flu. While most people are doing all they can to avoid the swine flu, some groups of people are said to be actively seeking it out.

These are parents who are reportedly arranging swine flu "parties" .

American Cancer Society Stands By Cancer Screening Guidelines

October 21, 2009
Group has no plans to rethink testing for breast, prostate tumors, contrary to published report. The American Cancer Society says it is not currently rethinking its stance on cancer screening, as was widely reported Wednesday.

"We are not redoing or rethinking our guidelines at this time, nor are we going to restate our guidelines to emphasize the inadequacies of screening," said Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society.

CDC Panel Says No to Routine Use of Gardasil for Boys

October 21, 2009
Doctors are free to offer HPV shot to males but widespread vaccination not advised. A U.S. advisory panel on Wednesday voted against the routine use of the vaccine Gardasil in boys and men, but did leave individual doctors free to recommend the vaccine for males as an option.

Sex With a Partner Makes Evolutionary Sense

Study

October 21, 2009
In worm model, genes gained from two parents helped offspring thrive, study shows. A new study in worms may help explain why reproduction via sex with a partner beats going it alone, evolutionarily speaking.

If a nematode worm wants to reproduce, they can do it one of two ways .

Radiation Treatments Made Safer for Cancer Patients

October 21, 2009
In mice, scientists say they can protect healthy tissue while radiating tumors. U.S. researchers say they may have found a way to protect healthy tissue and also increase tumor death when cancer patients undergo radiation therapy.

Swine Flu Still Strikes Younger People Hardest

October 20, 2009
90 percent of deaths since Sept. 1 were among those under 65, CDC says. The H1N1 swine flu epidemic continues to strike younger people, a U.S. health official said Tuesday, noting that nearly 90 percent of deaths since Sept.

Study Forecasts More Young Doctors in Future

October 20, 2009
But estimates on workforce date conflict, experts say. The future physician workforce in the United States may be younger but fewer in number than previously projected, a new study claims.

Researchers looked at physician employment trends by analyzing data in the American Medical Association Physician Masterfile and the U.S.

Seasonal Flu Vaccine Approved for Children

October 20, 2009
Fluarix sanctioned for kids aged 3 to 17 GlaxoSmithKline's seasonal flu vaccine, Fluarix, has been approved by the U.S. Food and Drug Administration for children aged 3 to 17, the agency said in a news release.

Votrient Approved for Advanced Kidney Cancer

October 20, 2009
Designed to thwart blood vessel growth in tumors Votrient (pazopanib) has been approved to treat advanced renal cell carcinoma, a form of kidney cancer in which cancerous cells invade the lining of small tubes in the kidney called tubules, the U.S. Food and Drug Administration said in a news release.

Gardasil Approved to Prevent Genital Warts in Males

October 19, 2009
Caused by human papillomavirus The U.S. Food and Drug Administration on Friday approved use of the cervical cancer vaccine Gardasil to prevent genital warts caused by human papillomavirus (HPV) types 6 and 11 in boys and men, ages 9 through 26.

U.S. Relaxes Opposition to Medical Marijuana

October 19, 2009
Prosecutors will no longer go after users or suppliers in states that permit use of the drug. The Obama administration has decided it will no longer prosecute medical marijuana users or suppliers, provided they obey the laws of states that allow use of the drug for medicinal purposes.

The new guidelines, which were to be sent in a Justice Department memo to federal prosecutors on Monday, are designed to give priorities to U.S.

Minnesota Pig Infected With H1N1 Flu

October 19, 2009
Federal officials say there's no danger in eating pork products. A pig that was shown at the Minnesota State Fair two months ago has tested positive for the H1N1 virus, making it the first case of a pig contracting the virus in the United States, federal officials said Monday.

The U.S.

PSA 'Nanotest' May Spot Prostate Cancer's Return After Surgery

October 19, 2009
Screen could boost accuracy but is still years away from approval, experts say. A new test that could revolutionize the treatment of men following prostate cancer surgery has worked well in a small, early trial, researchers report.

Using nanotechnology, the researchers were able to detect prostate-specific antigen (PSA), the cancer-associated protein, at levels far below what is now possible with older technology, explained Chad A. Mirkin, lead author of a report published online Oct.

More Doctors Need to Learn to Spot Skin Cancers

October 19, 2009
Resident physicians should be taught to screen for suspicious lesions, researchers say. Too few resident physicians have been trained in skin cancer examinations or watched or practiced the procedure, U.S. researchers report.

Micardis Given Wider Approval

October 19, 2009
For cardiac patients who can't take an ACE inhibitor Micardis (telmisartan) has received expanded approval from the U.S. Food and Drug Administration to reduce the risk of heart attack or stroke in people 55 or older who cannot take a class of cardiovascular drugs called ACE inhibitors, maker Boehringer Ingelheim said Monday.

Drugs for Inflammatory Bowel Might Increase Cancer Risk

October 19, 2009
Long-term use of thiopurines bears further study, researchers say. The use of thiopurine drugs to treat inflammatory bowel disease (IBD) increases the risk of cancers related to viral infection, according to a new study.

IBD includes Crohn's disease and ulcerative colitis. Thiopurine drugs are used to suppress the immune system in order to maintain remission in IBD patients.

Drinking Your Way to Health? Perhaps Not

October 18, 2009
Despite potential heart benefits, other risks await, experts warn. Just about every month .

11 More Children Die From Swine Flu

CDC

October 17, 2009
And vaccine production delays mean fewer shots will be available by month's end. Eleven more U.S. children died from H1N1 swine flu during the past week, a federal health official said Friday, adding that the disease is now so widespread it has surpassed epidemic proportions.

Race, Insurance May Affect Testing of Kids in ER

October 16, 2009
Study finds more done for youths with chest pain who are white and have private coverage. Black children and kids without private insurance are less likely than white children and those who do have private insurance to be given tests when seen for chest pain at hospital emergency departments, a U.S. study has found.

Strides Made in Tonsil Cancer Repair

October 16, 2009
New technique in palate reconstruction may make speaking, eating easier, study finds. Surgery on tonsil cancer patients can spell trouble for the palate, but now researchers say they've developed a technique that helps preserve the ability to speak clearly and eat most foods.

Traditionally, surgeons use big pieces of tissue to reconstruct the area after tonsil tumors are removed. But the patients who undergo this treatment can suffer "quality of life issues," study author Dr.

11 More Children Die From Swine Flu

CDC

October 16, 2009
And vaccine production delays mean fewer shots will be available by month's end. Eleven more U.S. children died from H1N1 swine flu during the past week, a federal health official said Friday, adding that the disease is now so widespread it has surpassed epidemic proportions.

New FDA Study Seeks Feedback on Lasik Surgery

October 16, 2009
Warnings issued to 17 centers for lax reporting of procedure-related adverse events. The percentage of patients who experience serious quality-of-life problems after Lasik eye surgery is being studied by the U.S. Food and Drug Administration, which has also issued warning letters to a number of Lasik facilities that weren't properly reporting problems with the procedure.

Breast Cancer Gene Tied to Diagnosis at Younger Age

October 16, 2009
Researchers concerned that disease may be developing earlier. Women with a high genetic risk of developing breast cancer are being diagnosed sooner than similar women in the past, which may suggest that tumors are developing earlier in the younger generation, researchers say.

The finding, presented at the 2009 Breast Cancer Symposium, held last week in San Francisco, could potentially affect how women are screened for breast cancer.

About 5 percent to 10 percent of breast cancer cases are thought to be connected to a genetic mutation that's also linked to ovarian cancer.

Cervarix Approved to Help Prevent Cervical Cancer

October 16, 2009
Vaccine blocks strains of human papilloma virus GlaxoSmithKline's Cervarix vaccine has been approved by the U.S. Food and Drug Administration to prevent the leading cause of cervical cancer, the Associated Press reported Friday.

Scientists Provide First Map of Complete Human Epigenome

October 16, 2009
The information may help accelerate research into diseases and treatments, experts say. Researchers have developed the first detailed map of the human epigenome, gaining greater understanding of the body's genetic makeup.

"In the past, we've been limited to viewing small snippets of the epigenome," Joseph Ecker, professor and director of the Genomic Analysis Laboratory at the Salk Institute for Biological Studies in La Jolla, Calif., and senior author of a new study, said in an institute news release.

Tylenol May Weaken Effectiveness of Kids' Vaccines

October 16, 2009
Giving analgesic to prevent fever at shot time could be counterproductive, researchers say. Fever after a vaccination is a normal and essential part of building an immune response, and giving children acetaminophen .

Suicidal Thoughts May Vary by Antidepressant

October 15, 2009
Men face higher risk when taking nortriptyline than escitalopram, study finds. Men who take the antidepressant nortriptyline (Aventyl) are nearly 10 times more likely to have suicidal thoughts than those who use the antidepressant escitalopram (Lexapro, Cipralex), a new study has found.

The study, published online Oct. 15 in BMC Medicine, included 811 people with moderate to severe unipolar depression.

Want Sun Protection? Wear Red or Blue

October 15, 2009
Fabric color affects absorption of UV radiation, researchers say. Deep blue and red cotton fabrics are better than yellow at protecting skin against damaging ultraviolet (UV) radiation from the sun, according to Spanish scientists.

The researchers said their findings could lead to clothing fabrics that offer improved sun protection.

The color of fabric is one of the most critical factors in determining how well clothing protects people against UV radiation.

Liver Cells Made to Order

October 15, 2009
Stem cell breakthrough may lead to better treatments, researchers say. Researchers have produced liver cells from the skin cells of people, potentially paving the way toward better treatments for those with liver disease.

"This is a crucial step forward towards developing therapies that can potentially replace the need for scarce liver transplants, currently the only treatment for most advanced liver disease," the study's lead author, Stephen A. Duncan, a professor of cell biology, neurobiology and anatomy at the Medical College of Wisconsin in Milwaukee, said in a news release from the college.

Fewer Genital Warts Thanks to HPV Vaccine Program

October 15, 2009
Australia sees a drop in cases following free Gardasil shots, researchers say. New cases of genital warts have declined sharply since vaccination of teen girls and young women against the human papillomavirus (HPV) began in Australia in 2007, a new study has found.

Certain types of HPV are linked with the development of cervical cancer.

Researchers analyzed data on new clients receiving treatment for genital warts at the Melbourne Sexual Health Center between 2004 and 2008.

Dialysis' Drawbacks Outweigh Benefits for Some Older Patients

October 14, 2009
Quality of life declined in nursing home residents who received artificial kidney treatment: study. Dialysis may not be worth undertaking for many older Americans in nursing homes who suffer kidney failure in addition to other ailments, a study finds.

The research, published in the Oct. 15 issue of the New England Journal of Medicine, found that this intervention failed to lengthen or improve most patients' lives.

Race Not a Factor if Breast Cancer Chemo Succeeds

October 14, 2009
All women have similar outcomes when there's no sign of disease following treatment, study finds. Among women with locally advanced breast cancer who undergo the same class of chemotherapy, race doesn't affect the odds of having no sign of disease at surgery, a new study finds.

Having no sign of the disease is considered a good sign that bodes well for a woman's prognosis, although it's not a guarantee that the cancer has vanished for good, the study authors noted.

"Our findings confirm [that having no sign of the disease] is a strong prognostic indicator and a surrogate for good survival, despite a patient's race, and that it's vital we continue to strive towards achieving this milestone for all women with breast cancer," said study co-author Dr.

Severe Swine Flu Could Lead to Blood Clots in Lungs

Study

October 14, 2009
Researchers say CT scans may be needed to spot the risk People who are severely ill with the H1N1 swine flu run the risk of blood clots in the lungs, University of Michigan researchers say.

And because standard chest X-rays may not be able to spot the potentially fatal condition, more sophisticated CT scans may be needed to identify the risk, the researchers said.

Technically called a pulmonary embolism, the condition occurs when one or more arteries in the lungs become blocked.

More MRI Machines May Mean More Back Surgeries

October 14, 2009
But many of these procedures will not help patients, researchers warn. Having easy access to MRI scans may be a bad thing for people with new-onset lower back pain, according to U.S. researchers.

Supervised Exercise May Relieve Fatigue During Chemotherapy

October 14, 2009
Mixed-intensity program improved vitality and well-being in study patients. Supervised exercise programs for cancer patients undergoing chemotherapy can reduce fatigue and boost muscle strength, aerobic capacity and emotional well-being, a new study suggests.

Fatigue is one of the most frequent and troublesome side effects of chemotherapy, the study authors noted.

The new study included 269 cancer patients, aged 20 to 65, at two hospitals in Copenhagen, Denmark.

Stem Cells Being Tested to Fight Pancreatic Cancer

October 14, 2009
It may be possible to stop tumor growth without harmful therapies, study suggests. New research is moving scientists closer to their goal of treating pancreatic cancer by killing tumors without hurting healthy tissue.

The researchers, who were scheduled to report their findings at the American College of Surgeons Clinical Congress, Oct. 11-15 in Chicago, have created a bioengineered "construct" that uses stem cells derived from bone marrow and a genetic product that stops tumor growth.

Health Tip

Help Control IBS Symptoms

October 14, 2009
Manage your diet and your emotional health Irritable bowel syndrome (IBS) occurs when the intestines squeeze too hard .

Impotence, Incontinence Risk Casts Doubt on High-Tech Prostate Surgery

October 13, 2009
Marketing is buoying use of the technique, researchers say, but surgeon's experience is key. Heightened risks for post-operative incontinence and impotence may outweigh any benefits from minimally invasive "keyhole" surgery for prostate cancer, a new study suggests.

The presumed good stemming from the robotic technique are being oversold to a public that is all too willing to believe, said Dr. Jim C.

Eye Problems Increasing in Preemies

October 13, 2009
As more pre-term infants survive, doctors see more babies with retinopathy of prematurity. Increased survival of extremely pre-term infants has led to a greater number of babies with vision problems caused by abnormal development of blood vessels in the retina, a new study finds.

Swedish researchers looked at data on 506 extremely pre-term infants (born before 27 weeks of gestation) who survived until their first eye examination and found that 368 (72.7 percent) had retinopathy of prematurity .

Many Hospitalized With Swine Flu Had Been Healthy

October 13, 2009
But the majority of cases still involve people with chronic problems, CDC says. While the majority of people hospitalized with the H1N1 swine flu have chronic medical conditions, many were healthy before coming down with the disease, a U.S. health official said Tuesday.

Study Suggests Link Between Cell Phones and Brain Tumors

October 13, 2009
Higher-quality data see danger from long-term use, new review finds. The latest study focusing on a possible cell phone-brain tumor connection finds a weak potential link between the two.

A review of existing research on the topic, published online Oct. 13 in the Journal of Clinical Oncology, discerned no overall link.

Mastectomy Not First Choice for Most Breast Cancer Patients

October 13, 2009
Three-fourths opt for breast-conserving treatments instead, study finds. Contrary to common belief, most women diagnosed with breast cancer are not turning to mastectomy as their first choice for treatment but are first trying more conservative approaches, such as lumpectomy, a new survey has found.

The survey, reported in the Oct. 14 issue of the Journal of the American Medical Association, also found that U.

Outbreak Investigation Highlights Drug Safety Issues

October 13, 2009
Noncompliance with manufacturing regulations led to contaminated syringes, report says. An outbreak of bloodstream infections in the United States a few years ago was caused by contamination of pre-filled heparin and saline syringes made by a company that wasn't following safety regulations, according to a new report that identified areas in medical monitoring systems that need to be improved.

Between October 2007 and February 2008, 162 bloodstream infections caused by the bacteria Serratia marcescens were reported at health-care facilities in nine states. An investigation traced the problem to pre-filled syringes from a single manufacturer.

Dogs Helping to Advance Cancer Research

October 13, 2009
Treatment for canine tumors may yield insight into therapies for people, researchers say. Ordinary dogs with cancer could provide crucial insight into the human forms of the disease, potentially leading to better treatments and screening for tumors, researchers from the U.S. National Cancer Institute report.

Many Americans Still Leery of Swine Flu Vaccine

October 13, 2009
But experts say it's as safe as the shot for run-of-the-mill seasonal flu. Even as the H1N1 swine flu vaccine is distributed coast to coast, many people say they have safety concerns that may stop them from getting vaccinated.

Although experts say those fears are unwarranted, a recent Associated Press-GfK poll found only about half of Americans said they are planning to get the vaccine. Most of those are older people .

Mother's Cancer Can Pass to Fetus

October 12, 2009
Genetic analysis is first proof this rare phenomenon occurs, scientists say. Over the past century doctors have suspected that cancers can spread from a pregnant woman to her fetus, but a genetically confirmed case reported this week from Japan suggests the phenomenon is real.

Mother-to-fetus transmission still likely rare, experts say, since the placenta acts as a barrier to cells from the mother, and the fetal immune system would reject and destroy cancer cells.

"Some 30 times reported in the past, mother and infant have appeared to share the same cancer, usually leukemia or melanoma," noted lead researcher Dr.

With Hormone Therapy, Tender Breasts May Signal Cancer Risk

October 12, 2009
Symptom might warrant a reassessment of treatment, experts suggest. Breast tenderness in women taking estrogen/progestin hormone replacement therapy could signal increased chances of developing breast cancer, a new study says.

Women taking estrogen plus progestin who reported developing breast tenderness after starting the hormone therapy were 48 percent more likely to develop invasive breast cancer than women on hormone therapy who did not experience breast tenderness.

Researchers said more study is needed before they would recommend that women who experience this symptom discontinue taking the hormones.

Drop in Certain Visual Skills May Precede Alzheimer's

October 12, 2009
Decline in spatial understanding can occur 3 years before diagnosis, study finds. The ability to perceive relationships between objects (visuospatial skills) may decline years before a person is diagnosed with Alzheimer's disease, a new study suggests.

It included 444 people who were dementia-free when they were enrolled in the study and underwent tests on a number of cognitive abilities, including visuospatial skills. The assessments were repeated at least once before the end of the study.

Berinert Approved for Rare Genetic Disease

October 12, 2009
To treats symptoms of hereditary angiodema Berinert (C1-esterase inhibitor) has been approved by the U.S. Food and Drug Administration as the first sanctioned treatment for a rare genetic disease called hereditary angiodema (HAE), the agency said in a news release.

Swine Flu Can Move Quickly to Severe Illness

October 12, 2009
Canadian, Mexican studies suggest U.S. hospitals need to be ready for surge of cases. Canadian and Mexican intensive care units were swamped with patients who rapidly became critically ill with H1N1 flu this past spring and summer, new reports find.

Many of these patients were relatively healthy adolescents and young adults who needed to be treated in an intensive care unit (ICU) within a day or two of being admitted to the hospital, note doctors from both countries. Many patients required mechanical ventilators, say the reports, slated to be published in the Nov.

A Little Cash Buys a Lot of Calories at the Corner Store

October 12, 2009
Kids are purchasing cheap junk food on way to and from school, survey finds. Kids who shop at the corner store before or after school purchase nearly 360 calories worth of food and beverage, on average, during each visit, according to a study of Philadelphia students.

Junk food is the most popular purchase, including chips, candy and sugar-sweetened beverages such as soft drinks, the study found. Results are in the November issue of Pediatrics.

Truckers Trailed By Risky Behaviors

Study

October 09, 2009
Long haulers at risk of sexually transmitted diseases and hepatitis C, researchers say Prevention programs for long-distance truck drivers may help reduce risky behavior that can lead to sexually transmitted infections (STIs), HIV and hepatitis C, say U.S. researchers.

76 Children Dead From Swine Flu

CDC

October 09, 2009
Finding highlights the need for kids to be vaccinated against the disease, experts say. Underscoring the threat that the H1N1 swine flu poses to children, U.S. health officials said Friday that 76 children have died from the disease since it appeared in April, including 19 in the past week alone.

HPV Tied to Rare Head-and-Neck Cancer

October 09, 2009
Origins of nasopharyngeal infection may mirror tonsil cancer epidemic, researchers say. Human papillomavirus (HPV) appears to be linked to an increase in cases of a rare type of head and neck cancer, a new study has found.

Nasopharyngeal cancer .

Face Masks for Patients May Leak, Spread Germs

October 09, 2009
Health-care workers should take precautions, especially given H1N1 pandemic, experts say. Health-care workers, take note: Hospital patients using positive pressure ventilation masks to help them breathe may be spreading germs every time they exhale, a new study finds.

The masks can leak exhaled air up to one meter from patients receiving treatments, spreading contagious respiratory illness within a hospital, researchers say. This may be of particular concern if the patient has the highly contagious H1N1 swine flu.

Vitamin D Good for Breast Cancer Patients

October 09, 2009
Supplements help fight treatment-related bone loss, researchers say. Many breast cancer patients have low levels of vitamin D, which could lead to weaker bones and increased risk of fractures, say U.S. researchers who recommend high doses of vitamin D for them.

'No Flu Shots for My Kids'

October 09, 2009
Some moms aren't convinced vaccines are necessary, safe or effective. Margaret Park, a mother of five, isn't having her kids vaccinated against seasonal influenza or H1N1 swine flu this year.

Park, a registered dietitian from Manassas Park, Va., is fighting the flu on her own terms .

Giving Gardasil to Boys Not Worth the Cost

October 09, 2009
But other experts dispute finding, and say young men need protection from STDs. The cost of giving boys the human papillomavirus (HPV) vaccine would outweigh any health benefit, researchers say.

Last month, a U.S.

Swine Flu May Bring Surge in Hospitalizations

October 08, 2009
In reports from Australia and U.S., most patients recovering, death rate same as seasonal flu. Potentially foreshadowing the U.S. experience this fall and winter, Australian and New Zealand health authorities who have just gone through their flu season report "substantial" traffic in their intensive care units as a result of H1N1 swine flu infections.

Shingles Raises Stroke Risk

Study

October 08, 2009
Patients with the virus should be monitored for high blood pressure, expert says. Adults with the skin disease shingles appear to be at raised risk for stroke, especially when it affects the area around the eyes, researchers report.

Previous reports have linked shingles with stroke risk, but "the exact frequency and risk for these phenomena are still unknown," said study lead author Dr. Jiunn-Horng Kang, a principal investigator in the Neuroscience Research Center of Taipei Medical University Hospital, Taiwan.

New Technology Shows Human Genome in 3-D

October 08, 2009
Technique lets researchers see how and where DNA fits into cells. The 3-D structure of the human genome has been deciphered by U.S. researchers, an achievement that improves understanding of genomic function and reveals how two meters of DNA can be packed into each human cell.

In Some Cities, Spring Swine Flu May Be Easing Fall Outbreak

October 08, 2009
Immunity from prior exposure may make H1N1's return less severe, experts say. New York, Philadelphia and other cities hit hard by H1N1 swine flu last spring aren't seeing as much of it now, even though outbreaks are occurring in all 50 states.

The possible reason: Many people in these spring-outbreak epicenters have already gained some immunity to H1N1, and this "herd immunity" is keeping a wider fall outbreak at bay, experts say.

According to a report released Thursday by the New York Times, health officials in New York City, Boston and Philadelphia say they are seeing less swine flu now than they did during the initial outbreak.

Many Childhood Cancer Survivors Never Marry

October 08, 2009
Certain forms of disease, treatment linked to greater likelihood of remaining single, study finds. Childhood cancer survivors are 20 percent to 25 percent more likely to remain unmarried than their siblings or people in the general population, a U.S. study has found.

HIV Patients More Prone to 7 Kinds of Cancer

October 08, 2009
Study found early treatment of infection could slow start of malignancies. The weakened immune systems of people with HIV puts them at increased risk for at least seven types of cancer, but early diagnosis and treatment of HIV infection could help delay the onset of some of these cancers, a new study suggests.

French researchers examined the incidence of three AIDS-defining cancers (Kaposi's sarcoma, non-Hodgkin's lymphoma and cervical cancer) and four non-AIDS-defining cancers (Hodgkin's lymphoma, lung cancer, liver cancer and anal cancer) in 52,278 HIV-infected people.

The study authors also analyzed the association between immunodeficiency, viral load, antiretroviral treatment and the onset of the seven cancers.

Stem Cell Research Offers Hope for Colon Cancer Vaccine

October 08, 2009
Mouse study suggests it may be possible to generate an immune response to cancer. Human stem cells may provide a means of creating a vaccine against colon cancer and other types of cancers, say American and Chinese scientists.

"Cancer and stem cells share many molecular and biological features. By immunizing the host with stem cells, we are able to 'fool' the immune system to believe that cancer cells are present and thus to initiate a tumor-combating immune program," Dr.

Liver Cancer Patients May Get Hope

October 07, 2009
Finding could help identify patients who will benefit from interferon therapy, researchers say. A short strand of RNA (microRNA) may help doctors identify liver cancer patients who would benefit from treatment with interferon, say U.S. and Chinese researchers.

'Lab on a Chip' Might Speed Breast Cancer Monitoring

October 07, 2009
Device makes measuring estrogen faster and simpler, researchers say. A pocket-size device under development could soon help monitor how well breast cancer treatments are working and help assess breast cancer risk by measuring levels of the hormone estrogen.

''We've developed a 'lab on a chip,' which is useful for making quantitative measurements of estrogen in samples of blood or tissue," said Aaron Wheeler, the Canada research chair of bioanalytical chemistry at the University of Toronto and a co-author of a report on the device in the Oct. 7 issue of Science Translational Medicine.

2nd Knee Surgery Common Among Young Patients

October 07, 2009
More active life raises risk for repeated rupture, researchers suspect. Younger people will probably need additional surgery after they've had damage to an anterior cruciate ligament repaired, a new study has found.

Women face a similar likelihood after damaging what's commonly called an ACL.

ACL damage is one of the most common types of knee injuries.

Potential Pieces of Autism Puzzle Revealed

October 07, 2009
Researchers identify possible genetic links, but urge further study. New genes and genomic regions that might be associated with autism have been identified by an international research team.

The researchers identified a single-letter change on chromosome 5 near a gene called semaphorin 5A, which is believed to help guide the growth of neurons and their long progressions, called axons. The activity of this gene appears to be reduced in the brains of people with autism.

Sebelius Urges Americans to Get Swine Flu Vaccine

October 07, 2009
HHS secretary says shots are made in same way as seasonal flu vaccine, and children are vulnerable to the disease. U.S. Health and Human Services Secretary Kathleen Sebelius renewed her call Wednesday for Americans .

Birth Control Pills Might Alter Mate Selection

Study

October 07, 2009
Review suggests it could hinder reproduction in the future. Could birth control pills be taking human evolution in a whole new, and possibly detrimental, direction?

A review of past research finds that, by altering hormonal cycles, the pill might affect choice of mates among members of both genders in a way that could hinder successful reproduction in the future.

"The use of the pill by women, by changing her mate preferences, might induce women to mate with otherwise less-preferred partners, which might have important consequences for mate choice and reproductive outcomes," said Alexandra Alvergne, lead author of a study appearing in the October issue of Trends in Ecology & Evolution.

"One prediction is that offspring of pill users are more homozygous than expected, possibly related to impaired immune function and decreased perceived health and attractiveness," according to the report by Alvergne, a postdoctoral research associate in the department of animal and plant sciences at the University of Sheffield in England, and colleague Virpi Lummaa.

Seasonal Flu Vaccine May Lessen Swine Flu Impact

October 07, 2009
But it won't fully protect people from the H1N1 virus, experts say. The seasonal flu vaccine may offer partial protection against the pandemic H1N1 swine flu, but not enough to prevent a person from catching the swine flu, Mexican researchers say.

In a study of hospital patients during the H1N1 epidemic in Mexico City last spring, the researchers found that those who had had a seasonal flu shot and were infected with the H1N1 flu had significantly milder cases than those who had not received a seasonal flu shot.

For the study, a group led by Dr.

Early Drug Treatment May Cut Multiple Sclerosis Risk

October 07, 2009
Improved rates of prevention or delay of full-blown disease seen in treated study patients. Among patients who show early signs of multiple sclerosis, treatment with a drug called glatiramer acetate appears to halve the risk that they will develop full-blown disease, new research suggests.

About 85 percent of patients who are diagnosed with multiple sclerosis first show signs of a "clinical event" that goes away. But many people who have this happen .

Officials Stress Safety as Swine Flu Vaccine Arrives

October 06, 2009
Shots are made in same way as seasonal flu vaccine; no serious side effects reported, CDC says As Americans begin to receive the first doses of the H1N1 swine flu vaccine, federal health officials stressed again Tuesday the product's safety.

During an afternoon press conference, the chief of the U.S.

Pain Robs Years From Folks at Mid-Life

October 06, 2009
People in their 50s act more like 80 if they're suffering: study. Middle-aged people who suffer from chronic pain face some of the same limitations that much older people do, with similar challenges for mobility or making it through daily chores, a new study finds.

Researchers looked at a 2004 study that examined 18,531 participants aged 50 and older. Twenty-four percent were often troubled by moderate or severe pain, and they had much more trouble coping with physical challenges of life.

Gene Test Might Predict Tamoxifen's Effectiveness

October 06, 2009
The breast cancer drug works better depending on particular DNA, study suggests. A genetic variant seems to predict resistance to the breast cancer drug tamoxifen, German researchers report.

The findings, which appear in the Oct. 7 issue of the Journal of the American Medical Association, could allow clinicians to predict which women will benefit most from the drug, which has been the gold standard of breast cancer care for the past 25 years.

Exercise in Adolescence May Cut Risk of Deadly Brain Tumor

October 06, 2009
Physical activity later in life didn't seem to matter, study finds. Exercising during adolescence may help guard against a deadly form of brain tumor in adulthood, new research suggests.

The study also found that avoiding obesity during the teen years was associated with a lower risk of developing the cancerous brain tumors called gliomas, while being tall increased the chances of such malignancies.

The study appears in the Nov.

Transplant Patients Should Be Monitored for Ear Infection

October 06, 2009
Transplantation failure can result from symptomless otitis media, research finds. Early diagnosis and treatment of ear infections can help avoid life-threatening complications for organ-transplant patients, a new study finds.

Researchers who reviewed the medical records of 3,278 organ-transplant patients in South Korea found that 2 percent had the ear infection known as chronic otitis media. Liver transplant patients accounted for 31 cases, kidney transplant patients for 28 and heart transplant patients for six.

Leafy Greens Top Risky Food List

October 06, 2009
Advocacy group notes illness outbreaks usually linked to 'healthy' foods. Leafy greens head a list of the top 10 riskiest foods regulated by the U.S. Food and Drug Administration, a report released Tuesday by a public advocacy group says.

Most Childhood Cancer Survivors Have Healthy Babies

October 06, 2009
But pregnancies should be closely monitored, researchers say. Most female and male childhood cancer survivors have normal pregnancies and healthy children, according to two U.S. studies.

Health Tip

Reduce Your Risk of Skin Cancer

October 06, 2009
Protect and check your skin The sun's rays may boost your mood, but they also contain harmful ultraviolet rays that can damage your skin and lead to skin cancer.

The American Academy of Family Physicians offers these suggestions to help reduce your risk:


Stay out of the sun, particularly when it's strongest, from 11 a.m.

Early H1N1 Vaccination Saves Lives, Cuts Costs

Study

October 05, 2009
Projects that inoculating 40% of population in October, November would blunt pandemic. To minimize deaths from the H1N1 pandemic swine flu, vaccination should start as soon as possible, a new U.S. study suggests.

Schools Provide Less Junk Food Today

CDC

October 05, 2009
Teens less likely to get soda, unhealthy snacks, but some states still lag behind, report finds. The amount of unhealthy foods and drinks available in American secondary schools has declined, especially in states with strong school nutrition standards and policies, says a federal government study released Monday.

Among 34 states that collected 2006-08 data, the median percentage of secondary schools that didn't sell soda, or fruit drinks that aren't 100 percent fruit juice, increased from 38 percent in 2006 to 63 percent in 2008. The median percentage of secondary schools that didn't sell candy, or salty snacks not low in fat, also rose from 46 percent to 64 percent, according to the U.

New Test Assesses Individual Breast Cancer Risk

October 05, 2009
Number of milk sacs, size of lobules determine findings, study shows. Analyzing individual breast tissue for specific structural characteristics may more precisely determine a woman's risk for developing breast cancer.

In the Oct. 5 online issue of the Journal of Clinical Oncology, researchers report that the more acini a woman has .

Noise Hurts Men's Hearing More, Study Shows

October 05, 2009
Married white guys are especially at risk for noise-induced hearing loss, research finds. New research suggests that men .

Gene Discovery May Advance Head and Neck Cancer Therapy

October 05, 2009
Expanded list of genetic links might improve diagnosis, treatment, researchers say. In a finding that could have a major impact on the diagnosis and treatment of one of the most deadly types of cancer, U.S. researchers have identified 231 potential new genes associated with head and neck cancer.

Focused Radiation Protects Tumor Patients' Brain Function

October 05, 2009
Researchers recommend standard treatment with monitoring over whole-brain radiotherapy. Brain tumor patients experience more learning and memory problems when whole-brain radiation therapy (WBRT) is added to standard stereotactic radiosurgery (SRS), researchers have found.

SRS delivers narrowly focused beams of radiation to the tumor site.

The study included 58 patients with one to three newly diagnosed brain metastases who were randomly selected to receive SRS alone (30 patients) or SRS plus WBRT (28 patients).

As TV Drug Ads Increase, So Do Concerns

October 04, 2009
Experts question commercials' value to patients and health-care system overall. You can't channel surf at all these days without stumbling across drug advertisements featuring happy people, sunny days, vague descriptions and a quickly mumbled list of side effects.

If you think you're seeing more of these ads than ever before, you're right.

The amount of money spent by pharmaceutical companies on direct-to-consumer advertising more than tripled between 1997 and 2005, growing from $1.

Dental Plaque Buildup May Raise Heart Risk in Black Men

October 02, 2009
White blood cell activity increases in these patients when oral hygiene is neglected, study finds. Black males may be at increased risk for heart problems caused by accumulation of dental plaque, a U.S. study finds.

New Classification Proposed for Stomach Cancers

October 02, 2009
Categorizing by pathway, not cell type, may lead to better treatments, researchers say. A new way to classify stomach cancers could lead to more effective treatments and improved long-term survival for people with the disease, researchers say.

For a study published online Oct. 1 in PLoS Genetics, the researchers analyzed 301 stomach tumors from people in Australia, Singapore and Great Britain, classifying the cancers according to the signaling pathways the tumors use to grow and spread.

Drug Combo May Prevent Heart Attacks, Strokes

October 02, 2009
'Inexpensive, well-proven medications' could have huge impact, expert says Giving daily doses of a statin and a blood pressure-lowering ACE inhibitor to people at high risk for a heart attack or stroke reduced their incidence by more than 60 percent in two years, researchers report.

People in the study all had diabetes or a history of cardiovascular disease, but the drug regimen probably could provide similar benefits to anyone vulnerable to cardiovascular trouble because of obesity, high blood pressure or simply old age, said Dr. R.

Half of U.S. Babies Living Today May Reach 100

October 05, 2009
Rising life expectancy shows no signs of slowing, researchers say. If current life expectancy trends continue, more than half of babies born in rich nations since 2000 will live to 100 years of age, and they'll have less disability than elderly people in previous generations.

That's the conclusion of researchers who found that increases in life expectancy evident in rich nations since 1840 show no signs of slowing.

"The linear increase in record life expectancy for more than 165 years does not suggest a looming limit to human lifespan.

Study Counters Warnings on Quit-Smoking Drug

October 02, 2009
No clear evidence found that Chantix has dangerous side effects, say UK researchers. The smoking cessation drug varenicline (Chantix) does not increase the risk for self-harm or depression, according to a new British study.

In July, the U.S.

Health Tip

Getting Cancer Support

October 02, 2009
It may help you feel more in control People struggling with a cancer diagnosis and treatment may need a lot of extra help and support.

The American Cancer Society offers these support suggestions for people with cancer, and their loved ones:


Find a support group that meets a local hospital, by telephone or online.
Enlist a nursing service that offers support, and if needed, home health care.

28 Pregnant Women Have Died From Swine Flu

CDC

October 01, 2009
Official calls the number 'upsetting'; flu shots and antiviral drugs urged for moms-to-be. Twenty-eight pregnant women in the United States had died from H1N1 swine flu as of the end of August, and 100 pregnant women had been hospitalized in intensive care, federal health officials said Thursday.

While the officials said they've never tracked deaths of pregnant women from seasonal flu, the number of deaths from the H1N1 flu could be significant.

"These are really upsetting numbers," Dr.

Children Need Seasonal Flu Vaccine, Experts Say

October 01, 2009
Study finds vaccination rates lag behind recommended levels. U.S. health officials continue to stress the need to vaccinate children against seasonal flu, as well as swine flu.

Anti-Aging Drug Closer to Reality

October 01, 2009
Scientists extend lifespan of female mice and thwart diseases of old age in both sexes. In a possible advance toward a treatment for aging in people, researchers report that by genetically modifying mice, they reduced their susceptibility to age-related disease and expanded the lifespan of female mice by 19 percent.

Scientists have known for decades that taking in fewer calories can extend lifespan in some animals, but they have yet to figure out why that is so. In this new study, published in the Oct.

Pre-Birth Exposure to 1918 Flu Raised Heart Risks, Study Finds

October 01, 2009
Whether same will hold true for current H1N1 strain remains a mystery. People exposed to the deadly 1918 Spanish flu pandemic while still in their mother's womb were about 20 percent more likely to have heart disease 60 years later, a new study has found.

The flu outbreak in 1918 killed 20 million to 40 million people worldwide, including 500,000 in the United States. That flu, like the current H1N1 swine flu pandemic, began as a mild disease, but it then came back in a much more lethal form.

Swine Flu Could Create Hospital Bed Shortage

October 01, 2009
Report finds demand could exceed supply in 15 states. There could be a shortage of hospital beds in 15 states if 35 percent of Americans get sick from the H1N1 (swine) flu virus, and 12 other states could reach or exceed 75 percent of their hospital bed capacity, a study released Thursday shows.

The number of people who could get sick with H1N1 flu in the United States ranges from a high of 12.9 million in California and a low of 186,434 in Wyoming, and the number of people who are hospitalized could range from a high of 168,025 in California to a low of 2,485 in Wyoming, according to the report from the non-profit group Trust for America's Health.

Children's Belly Aches Don't Disappear With Antidepressant

October 01, 2009
Elavil worked no better than placebo in study of kids with gastrointestinal disorders. Contradicting some previous research in adults, a new study suggests that the antidepressant amitriptyline (Elavil), is no better than a placebo at treating painful gastrointestinal disorders in children.

"The high placebo effect we identified in this study suggests that further studies of the use of certain antidepressants in children with functional bowel disorders are needed. While several trials have demonstrated a beneficial effect of antidepressants, including amitriptyline, for the treatment of irritable bowel syndrome in adults, more research is needed to determine how effective this drug is, if at all, in children," study author Dr.

CDC Links Infections With Swine Flu Deaths

September 30, 2009
Nearly a third of U.S. victims were also infected with pneumococcus or other bacteria, agency reports. Bacterial co-infections are common among people who have died of H1N1 swine flu in the United States and probably contributed to their deaths, according to a new federal government study.

Researchers from the U.S.

Non-AIDS-Related Cancers Growing Among HIV Patients

September 30, 2009
Possible reasons for increased rates explored by researchers. Non-AIDS-related cancers such as anal and lung cancer have become more common among HIV patients than among people without HIV since antiretroviral therapies were introduced in the mid-1990s to treat people with the virus, U.S. researchers say.

Breast Cancer Death Rates Continue to Drop 2% Annually

September 30, 2009
But mortality still higher among black women than white women, U.S. report says. Fewer women in the United States are dying from breast cancer, but disparities in death rates still exist between whites and blacks, a new report shows.

Deaths from breast cancer have dropped more than 2 percent each year since 1990. And in the past decade that decline in deaths has been shared by black, Hispanic and white women.

Sexual Satisfaction May Lead to Greater Well-Being in Women

September 30, 2009
But frequency of activity cannot be considered a reliable indicator, researchers say. Women who are happy with their sex lives have higher well-being scores and more vitality than women who are sexually dissatisfied, Australian researchers say.

Their study included 295 women, aged 20 to 65, who were sexually active more than twice a month.

"We wanted to explore the links between sexual satisfaction and well-being in women from the community, and to see if there was any difference between pre- and postmenopausal women," study author Dr.

Social Isolation Adversely Affects Breast Cancer

September 29, 2009
In mouse study, those living alone had larger tumors than those in groups. A socially isolated, stressful environment can speed up the growth of breast cancer, researchers studying the effects of stress in animal models reported Tuesday.

Social isolation can actually change the expression of genes important in the growth of mammary gland tumors, according to Dr. Suzanne D.

Eating in America Still Unhealthy

CDC

September 29, 2009
State-by-state report finds too few people meet fruit and veggie guidelines. Most Americans don't eat the recommended amounts of fruits and vegetables, says a U.S. government study released Tuesday.

Younger Women With Colon Cancer Outlive Men

September 29, 2009
Estrogen could explain discrepancy in survival rates, researchers say. A new study suggests that estrogen or other hormones could help younger women with colorectal cancer live longer than men with the disease.

"We've known for a while that estrogen prevents colorectal cancer, but this is the first study to suggest it may improve outcomes once you have colorectal cancer," said study co-author Dr. Heinz-Josef Lenz, co-director of gastrointestinal oncology and colorectal cancer at the University of Southern California/Norris Comprehensive Cancer Center, in a statement.

1918 Flu Closings May Provide Lessons for Today

September 29, 2009
Cities weighing swine flu school closures should review past practices, researchers say. An analysis of disease control measures used during the 1918 influenza pandemic offers lessons for dealing with the issue of school closures this fall in response to the H1N1 swine flu pandemic, say U.S. researchers.

Men Not Being Told Enough About PSA Tests

September 28, 2009
Pros, cons of cancer screen not understood, research shows. Most men are not being told the pros and cons of PSA tests, two new studies find.

Although PSA tests can detect prostate cancer, they can't predict which cancers are aggressive and which are so slow-growing that they don't need to be treated. This leads to overtreatment, which can have immediate consequences, such as impotence and incontinence, and only a tiny increase in survival, researchers say.

Docs Miss Test Results -- Even With Alerts

September 28, 2009
Communication woes still plague medical system, researchers find. Even an advanced, computerized medical-record system with alerts cannot guarantee that patients will receive timely follow-up care when imaging tests turn up signs of trouble, new research suggests.

"Our findings suggest that an electronic medical record that facilitates transmission and availability of critical imaging results to the health care provider through either automated notification or direct access of primary report does not eliminate the problem of missed test results even when one or more health care providers read the results," write the authors of a study in the Sept. 28 issue of the Archives of Internal Medicine.

More Women Having Other Breast Removed

September 28, 2009
But experts say there's no proof that procedure extends survival of cancer patients. Many more women are deciding to have a healthy breast removed after being diagnosed with breast cancer in the other.

But there's little evidence to suggest that this practice is actually beneficial in terms of improving survival, say the authors of a study published Sept. 28 in Cancer.

Scientists Discover How Chemo Can Make Women Infertile

September 28, 2009
But drug Gleevec counteracted effect in mouse study. Italian researchers say they have identified the mechanism by which chemotherapy can rob a woman of her ability to have children.

Intriguingly, the scientists also found that another anti-cancer drug might counteract the negative effects of the chemotherapy drug cisplatin.

The finding, demonstrated in mice and reported in the Sept.

Many Kids Suffer Medication Side Effects

Study

September 28, 2009
Adverse drug reactions cause more than half a million children's outpatient visits a year, researchers find. More than half a million kids a year are treated for medication side effects in American outpatient clinics and emergency rooms, according to new data.

Researchers at Children's Hospital Boston analyzed National Center for Health Statistics outpatient data between 1995 and 2005. Among children up to age 18, there were 585,922 visits a year for adverse drug events (ADEs).

Vitamin D May Improve Melanoma Survival

September 27, 2009
But levels are too low in many Americans, researchers say. Higher levels of vitamin D are linked to less severe, less deadly melanoma lesions in people with skin cancer, new research suggests.

The findings provide more support for the idea that vitamin D is crucial to skin health. Many Americans, however, don't get enough of it, perhaps because they limit sun exposure and drink less milk than in the past.

Swine Flu Virus Not Mutating, Making Vaccine a Good Match

September 25, 2009
Head of CDC calls that 'really good news.' The genetic makeup of the H1N1 swine flu continues to remain stable, making the forthcoming vaccine a "good match" for the virus, U.S. health officials reported Friday.

Exercise May Prevent Prostate Cancer

Study

September 25, 2009
Report adds to debate over the value of exercise as a protector for men. Regular exercise may help protect men from prostate cancer, says a new study.

U.S.

Stelara Approved for Psoriasis

September 25, 2009
Helps block overproduction of skin cells Stelara (ustekinumab) has been approved by the U.S. Food and Drug Administration for adults with moderate-to-severe plaque psoriasis.

Angst May Protect Against Some Skin Cancer

September 25, 2009
Study finds less squamous cell carcinoma in mice under short-term stress. Periods of short-term stress boost the immune system and protect against a certain type of skin cancer in mice, U.S. researchers say.

FDA Issues Health Alert on Kids' Tamiflu Dosages

September 25, 2009
Warning follows report that dosing instructions for liquid medication don't match syringe measurements. U.S. health officials have issued a public health alert to pharmacists and pediatricians about potential dosing errors involving liquid Tamiflu for kids.

Studies Find PSA Screening Unreliable

September 25, 2009
Men need to know pros, cons to make informed choice about prostate cancer test, experts say. The inability of the prostate specific antigen (PSA) test to distinguish between deadly and harmless prostate cancers makes it unusable as a population-wide screening tool, new research claims.

Because of its unreliability, results from the test lead to overdiagnosis and overtreatment, according to two reports in the Sept. 25 online edition of BMJ.

Folotyn Approved for Aggressive Type of Non-Hodgkin's Lymphoma

September 25, 2009
For those who have relapsed or haven't responded to other therapies The drug Folotyn (pralatrexate) has been approved to treat Peripheral T-cell Lymphoma (PTCL), an often aggressive form of non-Hodgkin's lymphoma, the U.S. Food and Drug Administration said Friday.

New Hope for Treatment of Pancreatic Cancer

September 25, 2009
By inhibiting key enzyme, researchers shrank tumors, prolonged survival in mice. Inhibiting the action of an enzyme called TAK-1 reverses pancreatic cancer resistance to chemotherapy, a finding that could lead to the development of a new way to treat the disease, researchers say.

Pancreatic cancer is resistant to every currently available anti-cancer treatment.

"During the past few years we have been studying the role played by a cytokine or regulatory protein called transforming growth factor-beta [TGFbeta] in the development of pancreatic cancer.

FDA Acknowledges Mistakes in Knee-Device Approval

September 25, 2009
Agency says it will review procedure for endorsing medical devices. The U.S. Food and Drug Administration violated procedures last year when it approved a knee repair device even though its own scientists recommended against approval, agency officials said Thursday.

New Treatment May Beat Melanoma

September 24, 2009
In trials, advanced cancers shrunk rapidly, researchers say. An experimental treatment for advanced melanoma promotes rapid shrinking of tumors, according to a new study.

The phase I extension trial includes patients with the cancer-causing mutation of the BRAF gene, which is associated with about 50 percent of melanomas and 5 percent of colorectal cancers.

The patients were given 960 milligrams of PLX4032 twice a day.

Letter Warns About Tricky Dosing With Liquid Tamiflu for Kids

September 24, 2009
Meanwhile, CDC says rapid test for swine flu not effective. Doctors warn that parents across the country could give the wrong dose of Tamiflu to their children as treatment for the H1N1 swine flu because the dosing instructions don't always coincide with the measurement markings on the syringe that comes with the liquid medication.

The warning letter, penned by scientists from Northwestern University Feinberg School of Medicine in Chicago, Emory University in Atlanta and Weill Cornell School of Medicine in New York City and published online Wednesday in the New England Journal of Medicine, also urges doctors and pharmacists to be on the lookout for this potential dosing mismatch and to help parents figure out exactly how much Tamiflu to give their child.

The authors cite a case that they say is probably happening all over the United States: The parents of a 6-year-old girl diagnosed with the H1N1 virus received a prescription for Tamiflu Oral Suspension that told them to give her three-fourths of a teaspoon of the medicine two times a day.

Steps Start to Add Up to a Math Path in the Brain

September 24, 2009
With functional MRIs, researchers see that numbers trigger distinct activity patterns. Careful observation and analysis of brain activity enables scientists to determine what number a person has just looked at or how many dots they've just been shown, a French study has found.

The researchers said their findings confirm the theory that numbers are encoded in the brain through detailed and specific activity patterns, something they say could help improve the investigation of humans' high-level numerical abilities.

While "number-tuned" neurons have been identified in monkeys, scientists previously had only been able to identify number-related brain regions in humans.

Minorities Less Likely to Have Blood Pressure Under Control

September 23, 2009
Blacks have the highest readings, despite taking medications, study finds. Blacks and Hispanics with a history of stroke or coronary artery disease have higher blood pressure than whites, while Hispanics are less likely to be prescribed medications to control it, a new U.S. study shows.

Leukemia Drug in High Dose Helps Survival

September 23, 2009
Two trials find daunorubicin benefits certain subsets of patients. Patients with acute myeloid leukemia (AML), take note: A new standard of care is emerging .

Injectable Vaccines More Effective for Adult Flu Than Nasal Sprays

September 23, 2009
Results may be different in children and in H1N1 swine flu vaccines, researchers say If you have the choice between a seasonal flu vaccine that comes in a nasal spray or an injection, go for the injection, new research shows.

In a study of adults tracked over one flu season, vaccines made from inactivated, or "killed," flu virus .

After-Effects of Chemotherapy May Include Memory Problems

September 23, 2009
Lack of concentration, thinking difficulties reported by breast cancer survivors, researchers say. Chemotherapy can save the lives of people with cancer, but new research suggests it may have devastating effects on the brain.

Many cancer patients who receive chemotherapy report "chemobrain" .

Cost Savings Adds to Value of Preventing Chronic Disease

September 23, 2009
Avoiding diabetes, high blood pressure can add years to life, researchers say. Prevention of chronic diseases such as diabetes, obesity and high blood pressure improves the lives of older Americans and also reduces medical costs, study findings show.

Researchers looked at a group of 51- and 52-year-olds from across the nation and projected their future state of health and medical costs if they could avoid developing certain chronic diseases. In a 51-year-old, prevention of obesity would extend life by 0.

Hand-Washing Habits Still Need Improvement

Survey

September 23, 2009
Soap industry gives America a B-minus for hygiene habits. You're doing better, America, but with only a "B-minus" grade in hand-hygiene habits, you've still got a ways to go, an industry-sponsored survey finds.

This year's results are up from a "C-minus" last year, but the fifth annual "Clean Hands Report Card," distributed by the Soap and Detergent Association, still finds room for improvement.

The good news: 50 percent of the 888 respondents to the August telephone survey said they wash their hands more than 10 times per day.

Hand Washing 10 Times a Day May Help Keep Flu Away

September 23, 2009
Hygiene, masks, quarantines all work to halt spread of viruses, review finds. Medications, personal hygiene, mask-wearing and quarantines all help prevent the spread of viral infections such as the flu, and researchers now suggest that the latter three strategies should be given more attention in plans to deal with pandemics.

In an update of a 2007 study, Dr. Tom Jefferson of the Cochrane Acute Respiratory Infections Group in Rome, Italy, and colleagues reviewed the results of 59 studies that looked at the effectiveness of strategies to reduce the spread of viral germs that cause respiratory diseases such as the flu and SARS.

Hormone Therapy for Prostate Cancer Raises Heart Risks

September 22, 2009
Treatment methods should take into account side effects, researchers say. Hormone therapy to treat advanced prostate cancer can increase the risk of heart disease, but some types of hormone therapy appear to be safer than others, new research has found.

The study included 30,642 Swedish men with either locally advanced prostate cancer or prostate cancer that had spread (metastatic cancer), who had received hormone therapy as primary treatment for their cancer.

The study findings were scheduled to be presented Tuesday at the European Cancer Organization meeting in Berlin.

Blood Tests May Spot Colon Cancer

September 23, 2009
Easier detection method might encourage more people to get screened, experts say. Simple blood tests may someday become a noninvasive and cost-effective way to detect colon cancer, two new studies suggest.

Researchers were to present studies in Berlin, Germany, on Monday that could offer an alternative to colonoscopy or fecal occult blood tests for diagnosing colorectal cancer, the second leading cause of cancer death in the United States and Europe.

"We have found biomarkers that can be used to screen for colorectal cancer," said Dr.

Leukemia Cells May Hide in Fat Tissue

September 22, 2009
Finding explains why obese children have higher relapse rates, researchers say. Leukemia cells can hide in fat tissue to evade chemotherapy, which may explain why obese children with leukemia are more likely to develop chemotherapy resistance and have higher relapse rates, researchers say.

A previous study found that obese children with leukemia are 50 percent more likely to relapse than lean children.

In this new study, researchers observed that obese mice with leukemia had higher relapse rates than lean mice after they were treated with the first-line chemotherapy drug vincristine.

Global Cooperation Urged to Control Species-Crossing Disease

September 22, 2009
Goal is to prevent zoonotic infection rather than just track outbreaks, experts say. A better-coordinated global system is needed to improve prevention, detection and responses to outbreaks of infectious diseases that can be transmitted between animals and humans, according to a new report released Tuesday by the U.S. Institute of Medicine and the National Research Council.

Sex With New Partners Raises Widowers' Disease Risk

September 22, 2009
Erectile dysfunction drugs may have boosted seniors' sexually transmitted infection rates, researchers say. Older widowers who recently lost their wives are more likely to have a sexually transmitted disease than their counterparts who are still married, a new study has found.

The researchers behind the study add that drugs like Viagra could boost the risk, noting the widowers might be seduced by advertisements for sexual enhancement.

The risk that seniors have a sexually transmitted disease remains extremely low, at less than 1 percent, study co-author and Harvard researcher Kirsten Smith explained in a news release about the study.

Could Swine Flu Panic Be Worse Than Outbreak Itself?

September 22, 2009
With infections typically causing only mild illness, experts point to exaggerated fears as the real threat. With all the warnings and preparations, dire predictions and hastily ordered vaccines, could the growing worry about H1N1 swine flu prove more disruptive than the actual outbreak?

That notion is weighing on the minds of more than a few infectious-disease experts as the fall and winter flu season looms.

Not only does societal panic not help during a public health situation, such as the current H1N1 flu pandemic, it can actually backfire, creating its own set of problems, the experts said.

"We have limited resources in the U.

Flu Can Raise Chances of Heart Attack

September 22, 2009
Vaccine reduces risk of deaths related to heart disease, study shows. People suffering from the flu may be at higher risk for having a heart attack, especially those with heart disease and diabetes, British researchers report.

Because both seasonal and the pandemic H1N1 swine flu are circulating this fall and winter, people at risk for heart attacks are urged to get a seasonal flu shot and an H1N1 flu shot, which may reduce the chance of getting the flu and thereby lower the risk for a heart attack, experts say.

"Influenza is most concerning because of its secondary complications," said Dr.

Immune Cells Offer Hope for Injured Lungs

September 21, 2009
Discovery in mice shows promise for treating potentially fatal wounds, researchers say. New research in mice is shedding light on how a special group of immune cells heal badly injured lungs. The next step is to find a way to boost the cells in patients or get them to work harder when needed, researchers say.

"Our study results are the critical first leads in finding treatments for a clinical condition that until now has had none, despite its high mortality," study senior investigator Dr.

Mishandling Money May Foreshadow Alzheimer's

September 21, 2009
Trouble writing checks, paying bills preceded dementia, study found Money management difficulties may be a sign that people with mild memory problems will soon develop Alzheimer's disease, a new study suggests.

It included 87 older people with mild cognitive impairment, and 76 others with no memory problems. All the participants took a money management test at the start of the study and again one year later.

Many Teens Circumvent Tanning Bed Laws

September 21, 2009
Though operators largely follow the rules, the laws are too lax, study shows. Tanning bed operators appear to be largely abiding by parental consent laws, but the laws don't go far enough in limiting teens' exposure to harmful ultraviolet rays, a new study shows.

Tanning bed operators told data collectors posing as 15-year-old girls that as long as they had parental consent, they could tan as often as they wished, the researchers said.

That runs counter to a U.

Head, Neck Cancer Treatment Often Not Completed

September 21, 2009
Surgical patients more likely to finish radiation course, study finds. Incomplete and interrupted radiation treatment is a common problem among Medicare patients with head and neck cancer, a new study has found.

Researchers analyzed data from 5,086 Medicare patients diagnosed with head and neck cancer between 1997 and 2003 and found that nearly 40 percent of them experienced interruptions in radiation therapy or failed to complete the course of therapy.

People who had surgery before radiation treatment were more likely to complete the treatment without interruption than were those who did not have surgery (70 percent versus 52 percent).

1 Swine Flu Shot Enough for Older Kids

September 21, 2009
But children under 10 will need two doses, preliminary U.S. trial results show. Kids who are between 10 and 17 years old will apparently need only one shot of the H1N1 swine flu vaccine, according to initial results of ongoing trials, U.S. health officials announced Monday.

Researchers Propose Improved Cervical Cancer Screening

September 21, 2009
New method uses risk estimation to guide management, experts say. A new tool to determine a woman's risk of developing cervical cancer is being developed by researchers at the U.S. National Cancer Institute.

Older Brains May Not Be So Small After All

September 21, 2009
Decrease in gray matter isn't a given, researchers find. Scientists have assumed that people's brains shrink as they age, but researchers now suspect that's not the case.

A study in the September issue of Neuropsychology examines long-term Dutch research into aging brains, which used neurological tests and MRI scans to measure parts of the brain.

The researchers looked at data from 1994 to 2005 for two groups: 35 people who were cognitively healthy and 30 people who did not have dementia but experienced cognitive decline during the time period.

New Chemo Regimen May Benefit Ovarian Cancer Patients

September 20, 2009
Dose-dense treatment improved survival, but too toxic for some: study. Dose-dense chemotherapy improves survival in women with advanced ovarian cancer, Japanese researchers say.

Currently, paclitaxel and carboplatin given every three weeks is considered standard first-line chemotherapy for advanced epithelial ovarian cancer. However, dose-dense weekly treatment with paclitaxel is seen as a way to increase progression-free and overall
survival in these patients, according to the new study findings.

Hormone Therapy May Make Lung Cancer More Likely

September 20, 2009
Expert says finding supports doubts about value of treatment. Taking a combination form of hormone replacement therapy, which includes both estrogen and progestin, increases a woman's risk for dying from lung cancer, a new study has found.

The finding stems from an analysis of data from the Women's Health Initiative trial on 16,608 postmenopausal women, aged 50 to 79, in the United States who had been randomly assigned to take either a once-daily tablet of 0.625 milligrams conjugated equine estrogen plus 2.

New Drug May Offer Hope to Some With Lung Cancer

September 20, 2009
Pemetrexed improves survival with advanced non-small-cell tumors, study finds. Maintenance therapy with the drug pemetrexed improves the survival of people with non-small-cell lung cancer whose disease has not progressed after chemotherapy, a new study has found..

1st Doses of Swine Flu Vaccine Set for Early October

September 18, 2009
Initial vaccine will be a nasal spray, followed shortly by injectable one: CDC. The first doses of the H1N1 swine flu vaccine will start shipping the first week in October, slightly earlier than expected, U.S. health officials said Friday.

Swine Flu Shots Safe for People With Weak Immune Systems

Experts

September 18, 2009
Another study outlines risks of catching H1N1 from various routes. The H1N1 swine flu vaccines approved this week by the U.S. Food and Drug Administration can be safely used by people with compromised immune systems, according to new recommendations from the American Academy of Allergy, Asthma & Immunology.

Middle-Age Heart Risk Factors Shorten Men's Lives

September 18, 2009
Smoking, hypertension, high cholesterol cut 10 years of life, study finds. Middle-aged men with risk factors for heart disease such as smoking, high blood pressure and high cholesterol are taking 10 to 15 years off their lives compared to men without these troubles, British researchers say.

Although death from heart disease has been declining, in part due to better control of cardiovascular risk factors and better care, this is the first study that looks at death from heart disease in terms of life expectancy, the researchers said.

"The good news is that all of us can make changes to live a healthy life," said lead researcher Dr.

Scientists May Know How Lung Cancer Spreads

September 17, 2009
Preventing metastasis 'could have a huge impact on survival,' researcher says. New insight into how primary lung cancer turns into invasive, or metastatic, cancer could lead to treatments that improve patient survival, U.S. scientists say.

Swine Flu Loves a Crowd

September 17, 2009
But there are ways to reduce your risk even in close quarters, experts say. With the H1N1 swine flu virus lurking in every nook and cranny, all Americans should be on guard this coming flu season.

But experts say those living and working in crowded locales .

Hepatitis B Vaccination Protects Against Liver Cancer

September 16, 2009
Immunization program for newborns has lasting effects beyond childhood, researchers say. Vaccination at birth against hepatitis B virus greatly reduces the risk of liver cancer in young adulthood, new research suggests.

In a 20-year study that followed infants who were vaccinated against the liver disease in Taiwan beginning in 1984, when a universal vaccination program went into effect, Dr. Mei-Hwei Chang, of the Department of Pediatrics at the National Taiwan University Hospital in Taipei, and colleagues looked at young people who had developed liver cancer.

Timing, Type of HRT May Determine Breast Cancer Risk

September 16, 2009
Starting estrogen-progestagen therapy early may up odds of disease, study shows. The timing and type of hormone replacement therapy women take to relieve menopausal symptoms seem to determine the degree of breast cancer risk they face, a new French study suggests.

Overall, starting estrogen-progestagen therapy soon after menopause appears to boost the risk of breast cancer, even when only used for short periods of time, according to the study, which was published in the Sept. 14 online issue of the Journal of Clinical Oncology.

Blacks Fare Worse After Cardiac Arrest

September 15, 2009
Poor hospital care a big reason why, researchers say. Black patients who suffer cardiac arrest in the hospital are much less likely to survive than white patients, a new study finds.

Most of this disparity appears to result from the hospital in which black patients receive care, although other factors play a role as well, the researchers said.

"We know that survival after having a cardiac arrest in the hospital setting has always been historically low," said lead researcher Dr.

Watchful Waiting Works for Older Men With Prostate Cancer

September 15, 2009
But experts stress the same does not hold true for patients under 60. Older men diagnosed with prostate cancer who choose watchful waiting are doing better these days than in the era before screening with a test for prostate-specific antigen (PSA) became common, a new study finds.

"The most important message is that the long-term outcome for patients who don't have surgery or radiation is pretty good," said study author Dr. Grace L.

Celiac Disease May Raise Risk of Dying

September 15, 2009
People with with mild form of the digestive disorder have slightly higher death rate, study shows People with milder symptoms of celiac disease face a slightly higher risk of dying than other people, a new study finds.

Cancer and heart disease were the main causes of death in the patients studied, and the risk was higher in people who had had small-intestinal biopsies in childhood, the researchers found.

Celiac disease affects about 1 percent of people in the Western world, the researchers said, and it is triggered by exposure to gluten, a protein found in barley, wheat and rye.

FDA Approves 4 Swine Flu Vaccines

September 15, 2009
Agency expects first batches to be available within a month. The U.S. Food and Drug Administration on Tuesday approved four H1N1 swine flu vaccines, with the first doses expected to be available within four weeks.

Gene 'Switch' May Help Drive Excess Fluid in Lungs

September 15, 2009
Finding could lead to treatments for bronchitis, asthma, researchers say. The discovery of a genetic switch that makes mucus production go into overdrive could potentially lead to better treatments for chronic lung ailments, a new study says.

Excessive mucus production in the lungs can cause illness or death from asthma, cystic fibrosis, bronchitis, common colds and other illnesses. From a biological perspective, it's unclear why the body creates dangerous levels of mucus, the researchers noted in the Sept.

For Hispanics, a Unique Cancer Profile Emerges

September 15, 2009
Report finds they're less likely to die of cancer but more apt to have certain malignancies. Hispanics in the United States are less likely to die from cancer than non-Hispanic whites, but they have higher rates of cancers linked to infections, including stomach, liver and cervix malignancies, a new report says.

At first glance, Hispanics' lower death rate from cancer seems to be good news, but one explanation is that the Hispanic population skews younger than the general U.S.

Small Businesses Urged to Prepare for Swine Flu

September 14, 2009
Advance planning may help to minimize disruptions, officials say. With cases of H1N1 swine flu continuing to rise, U.S. health officials on Monday urged small businesses to prepare now to keep their shops running if the flu season turns severe.

Medications That Lower Breast Cancer Risk Carry Other Dangers

September 14, 2009
Analysis notes tamoxifen, raloxifene can up chances of other cancers, clots. Medications given to women at high risk for developing breast cancer do reduce their cancer risk, but the drugs carry other health risks, a new analysis suggests.

That was the conclusion of researchers who looked at numerous published studies, including randomized clinical trials and a head-to-head assessment of the medications used for risk reduction. Those include tamoxifen, raloxifene and tibolone.

Too Few Latinos Get Colorectal Cancer Tests

September 14, 2009
Language barrier could explain lower screening rates, researchers say. Language barriers may contribute to lower screening rates for colorectal cancer among Mexican-Americans, a San Diego State University study suggests.

A 2005 telephone survey of close to 17,000 older Californian residents found that two thirds of those of Mexican descent needed another person to help them talk with doctors .

Common Diabetes Drug May Fight Cancer

September 14, 2009
Metformin-chemo combination shrinks tumors, delays recurrence in mice: study Adding the widely used diabetes drug metformin to conventional chemotherapy shows promise for treating and delaying recurrence of breast cancer, new research suggests.

In lab tests using mice with breast cancer, researchers found that the drug combination suppressed the cancer stem cells thought to drive tumor progression.

"We discovered that metformin selectively kills cancer stem cells.

Routine Testing Would Improve Herceptin Use in Breast Cancer

September 14, 2009
Targeted drug therapy often doesn't reach the right patients, study finds. New research suggests that the anti-breast cancer drug trastuzumab, also known as Herceptin, isn't reaching its full potential. Many patients aren't receiving tests that determine whether it's appropriate or are taking it when they don't need to.

Under current guidelines, women with breast cancer in its early stages should receive tests to see if Herceptin might be appropriate for them.

Depression May Hasten Cancer Death

September 14, 2009
Psychological screenings and treatment are warranted: study. An analysis of research suggests that depression can rob people with cancer of years of life, raising questions about the need to screen patients for psychological problems.

"We found an increased risk of death in patients who report more depressive symptoms than others and also in patients who have been diagnosed with a depressive disorder compared to patients who have not," said University of British Columbia graduate student Jillian Satin, co-author of a study published online Sept. 14 in the journal Cancer.

Swine Flu Trials Continue to Point to 1-Dose Vaccine

September 11, 2009
U.S. reports unusually high flu activity, most of it swine variety. U.S. health officials said Friday that additional trials of the H1N1 swine flu vaccine continue to find that a single dose produces a strong immune response in healthy adults.

Ovarian Cancer Test Approved

September 11, 2009
Helps doctors decide on appropriate surgical options The U.S. Food and Drug Administration has approved a new test for women with pelvic tumors that are known to need surgery.

Scientists Spot Key to Breast Cancer Spread

September 11, 2009
Combination of proteins sparks disease growth, research shows. Too much of two proteins can send noninvasive breast cancer into a deadly spread through the body, researchers say.

In a study at the University of Texas M.D.

Two Genes May Determine How Well MS Patients Do

September 11, 2009
Study in mice provides clues to variations in disease progression. Two genes in mice have been linked to improvements in the body's ability to repair itself when afflicted with multiple sclerosis, potentially leading to more effective treatments, a U.S. scientist reports.

One Dose of Swine Flu Vaccine Offers Protection

Studies

September 11, 2009
Findings could expand vaccine supply and speed immunity, experts say. Preliminary tests of an H1N1 swine flu vaccine conducted in Australia and Britain show that a single dose creates enough antibodies to protect against the virus within about 10 days.

That's a potentially significant development, because it was thought that two shots would be needed to provide full immunity to the virus. A one-dose protocol would greatly expand the supply of vaccine and hasten individual immunity.

Environment May Play Role in Racial Health Disparities

September 10, 2009
Society affects biology, researchers say. The differences in health between racial groups may have more to do with how people look at each other than with genetics, a new study suggests.

"We have to take seriously the way race shapes people's experiences, the environments they live in and their life chances," study author Clarence C. Gravlee, an assistant professor of anthropology at the University of Florida, said in a university news release.

Doctor-Patient Talk May Help Blacks With Hypertension

September 10, 2009
Lack of communication during office visits may affect outcomes, study finds. Black patients with high blood pressure often seem to struggle to communicate with their doctors, potentially leading to worse disease outcomes, a North Carolina study suggests.

"It seems that in general, blacks talk less overall to their physicians than white patients," study author Dr. Crystal Wiley Cene, an assistant professor at the University of North Carolina School of Medicine in Chapel Hill, said in a university news release.

Get Your Vaccine for Seasonal Flu, Experts Urge

September 10, 2009
The regular winter scourge poses a potential threat, just like swine flu. Swine flu may be grabbing all the headlines, but seasonal flu poses a real threat this fall, too.

And the time to act is now, by getting a seasonal flu shot. Then follow it up with an H1N1 swine flu vaccine when the first shipments arrive in mid-October.

Deep Sea Microbes Shed Light on Human Biology

September 10, 2009
Scientists determine structure of enzymes involved in making ribosomes. By studying microbes that live near the boiling thermal vents of the deep sea, scientists have identified the structure of an RNA and protein enzyme that is key to making human ribosomes, new research shows.

Ribosomes, a component of all cells that have a nucleus, are responsible for translating the information encoded in DNA into proteins that are crucial for biological processes.

In their study, researchers from Yale University studied Methanocaldococcus jannaschii, a microbe considered an "extremophile" because it thrives in harsh conditions, including in Antarctic ice and at the bottom of the ocean.

Swine Flu Burrows Into Lungs

Study

September 10, 2009
Unlike seasonal flu, H1N1 goes deep into respiratory tract, researchers confirm. New British research confirms previous reports that the H1N1 swine flu goes deeper into the lungs than ordinary seasonal flu, possibly explaining why it's often more severe in some people.

"Most people infected with swine-origin flu in the current pandemic have experienced relatively mild symptoms," Ten Feizi, a professor at Imperial College London and co-author of a study released Thursday, said in a college news release. "However, some people have had more severe lung infections, which can be worse than those caused by seasonal flu.

Treating Childhood Leukemia With Fewer Side Effects

September 10, 2009
Dutch researchers skip radiation treatments, some chemo but add corticosteroid. Adding the corticosteroid dexamethasone to the treatment regimen of children with acute lymphoblastic leukemia improves survival rates and reduces the incidence of the cancer recurring, a new Dutch study shows.

Acute lymphoblastic leukemia (ALL), a cancer of the blood, is the most common childhood cancer and is highly treatable, according to background information in the study.

But the researchers say that many children with ALL are over-treated with cranial radiation and chemotherapy drugs that cause significant side effects and may not be necessary to cure them.

Swine Flu Shots May Come Too Late to Stem Fall Outbreak

Study

September 10, 2009
Scientists' projections have infections peaking in mid-October, ahead of vaccine delivery. The height of this year's fall H1N1 swine flu outbreak is expected in October, but a planned vaccine may arrive too late to stop it, a new study suggests.

The first batch of the new H1N1 vaccine, totaling only 45 million doses, is not expected before mid-October, according to the U.S.

Allergies Dampen Sex Lives

September 10, 2009
Study finds 83 percent of people with allergic rhinitis say it kills the mood. Having allergies can take a toll on your sex life, new research shows.

When polled, 83 percent of people with allergic rhinitis said it affected their sexual activity at least sometimes, with almost 18 percent of those affected saying their allergies nearly always got in the way of a satisfying sex life.

"I was kind of surprised that it made that much of a difference," said study author Dr.

Scientists Find Clue to Dangerous Side Effect of MS Drug

September 09, 2009
Tysabri appears to awaken dormant, common virus that crosses over into brain. Scientists may have discovered part of the reason why Tysabri, a drug used to treat multiple sclerosis, may lead to the development of a rare but potentially deadly brain disease in some patients.

The drug seems to rouse the typically dormant JC virus from its slumber, allowing it to cross into the brain.

Although this finding may lead to a way of predicting who is at risk for the brain infection .

Brain Scans Could Help Spot Schizophrenia Earlier

September 09, 2009
Imaging technology might advance treatment of psychotic disorders, researchers say. Scanning technology has helped researchers pinpoint the part of the brain that appears to be where psychotic disorders such as schizophrenia begin, a new study says.

The research could help doctors diagnose these types of disorders in their early stages and help scientists develop more effective drugs, according to the report in the Sept. 7 issue of the Archives of Psychiatry.

Getting Closer to the Origins of Prostate Cancer

September 09, 2009
Newly discovered stem cell, common STD could help spur tumors, studies find. Two studies take significant steps toward solving major mysteries about prostate cancer .

New Vaccine May Work Better Against Lung Disease

September 09, 2009
Different formulation seems to thwart pneumonia in high-risk group with COPD, study finds. A recently developed pneumonia vaccine may be more effective in preventing infections in patients with chronic obstructive pulmonary disease (COPD) than the vaccine that is typically used, new research suggests.

Risk of pneumonia can be an ongoing problem for people with COPD, a chronic, progressive disease that causes difficulty breathing and chest tightness. The U.

Chinese 'Devil Dung' Plant Could Be a Swine Flu Fighter

September 09, 2009
Extract used in 1918 pandemic may have antiviral properties, scientists say. A plant with a particularly malodorous sap has components that show great efficacy in killing off the H1N1 swine flu virus, Chinese scientists report.

The plant, Ferula assa-foetida, grows throughout Iran, Afghanistan and mainland China, and is commonly dubbed "Dung of the Devil" due to its ill-smelling sap. But the researchers note that the plant was used in China against the influenza virus during the great 1918 Spanish flu epidemic, which is thought to have killed tens of millions worldwide.

FDA Panel Backs Giving HPV Vaccine Gardasil to Young Males

September 10, 2009
The advisors also recommend approval of second HPV vaccine, Cervarix, to prevent cervical cancer. U.S. drug advisors recommended Wednesday that use of the vaccine Gardasil, already administered to help prevent cervical cancer in women, be expanded to help prevent genital warts in young males.

Antiviral Drugs Should Be Used Cautiously to Fight Flu, U.S. Says

September 08, 2009
Most people won't need medicines like Tamiflu or Relenza, according to CDC. Antiviral medications such as Tamiflu and Relenza, which are effective in treating the H1N1 swine flu, should be taken only by people hospitalized with the flu or those at high risk for complications from the disease, U.S. health officials said Tuesday.

Gene Linked to Liver Disease in Cystic Fibrosis

September 08, 2009
Screening for the variation could help identify risk factors early on, researchers say. A variant of a particular gene in people with cystic fibrosis greatly increases their chances of developing severe liver disease, new research shows.

Cystic fibrosis is an inherited disorder that can lead to deadly lung infections and digestive problems.

About 3 percent to 5 percent of the 30,000 people in the United States with the condition will also develop a serious form of liver disease, including cirrhosis and portal hypertension, or high blood pressure caused by obstruction in the liver, according to the Cystic Fibrosis Foundation.

Metozolv Approved for Diabetic Stomach Disorder, GERD

September 08, 2009
But long-term use could cause serious side effects Metozolv (metoclopramide) has been approved by the U.S. Food and Drug Administration to treat diabetic gastroparesis and gastroesophageal reflux disease (GERD), drug maker Salix Pharmaceuticals said Tuesday.

FDA to Require Faster Reporting of Food-Safety Problems

September 08, 2009
Companies must alert agency of potential trouble within 24 hours. All companies that manufacture, process or distribute food for people or animals to eat must now report any problems that could lead to food-borne illness within 24 hours, the U.S. Food and Drug Administration announced Tuesday.

Scientists Spot Clue to Cancer's Aggressiveness

September 08, 2009
They hope molecular signature shows when disease will respond to cancer drug. Researchers say they have gained insight into whether certain aggressive cancers .

Gum Disease May Increase Head and Neck Cancer Risk

September 08, 2009
The threat seems the same for smokers, nonsmokers, study finds Taking good care of your teeth may help cut your risk of developing head or neck cancer, suggests a new study that links a gum disease to such tumors.

Having chronic periodontitis, a gum disease involving the progressive loss of the bone and soft tissue attached to the teeth, appeared to increase one's odds of developing head and neck squamous cell carcinoma, especially in the mouth and throat.

The findings was published online Sept.

Virus May Drive Some Prostate Cancers

September 08, 2009
Testing for XMRV might help spot more aggressive disease, experts say. A new study tightens the suspected link between a virus and prostate cancer, and raises the possibility that infection with the virus could be an indicator of aggressive tumors that require swift treatment.

"We're not making any causal association at this moment," stressed Dr. Ila R.

Colleges Move to Limit Swine Flu's Spread

September 08, 2009
Numbers of infections on campus already increasing rapidly; could be preview of what's to come for general population. Erica Goldfine, a senior at American University in Washington, D.C., returned to school this semester to find a new item in her college handbook, right after academic policies on cheating: emergency preparedness procedures for the H1N1 swine flu.

Colon Cancer Screenings Still Too Low

Study

September 08, 2009
Even when Americans have health care 'safety net' in place, rates barely budge, report finds. Despite highly publicized education campaigns and widespread agreement about the importance of colorectal cancer screening, only 61 percent of Americans who should be screened do so, new research finds.

Rates for minorities, the uninsured and other vulnerable groups are lower still, with only 22 percent of lower-income people served by a "safety net" health system in Texas being screened.

Using data from a health system in Tarrant County, Tex.

U.S. Issues Swine Flu Guidelines for Day-Care Programs

September 04, 2009
Vaccination, good hygiene practices are among the recommendations to protect young children. Since children under the age of 5 are at particular risk for complications from the H1N1 swine flu, U.S. health officials issued new guidelines Friday designed to limit the spread of the virus in early childhood programs, such as day-care centers and Head Start programs.

Swine Flu Vaccine Seems Safe

Experts

September 04, 2009
So far, trials show no problems and shot should be as safe as that for seasonal flu, officials say. Despite persistent public concern that H1N1 vaccines being tested might have unforeseen side effects, experts reiterated Thursday that so far, at least, the shots seem safe.

"There have been no red flags at all," Dr. Anthony Fauci, director of the U.

Giving Swine Flu Drug by IV Could Save Lives

September 04, 2009
British case supports using Relenza in this as-yet-unapproved form, experts say. A 22-year-old cancer patient battling for her life after contracting H1N1 swine flu recovered fully after doctors took the unorthodox approach of giving her the antiviral drug Relenza intravenously.

The British physicians who treated the woman said this last-resort approach may need to be considered for others as swine flu sweeps the globe. Relenza is licensed in pill form and as an inhaled powder, but not as an intravenous medication.

Swine Flu Poses Risk to Kids With Neurological Conditions

September 03, 2009
But U.S. officials say death rate seems no higher than with seasonal flu. Nearly 500 Americans have died of complications from the H1N1 swine flu since the virus first surfaced last spring, including at least 36 children younger than 18, a new government report shows.

And 67 percent of those children who died had at least one chronic high-risk "neurodevelopmental condition," such as epilepsy, cerebral palsy or developmental delay, U.S.

Intuniv Approved for Pediatric ADHD

September 03, 2009
No known potential for abuse, maker says Intuniv (guanfacine) has been approved by the U.S. Food and Drug Administration to treat Attention-Deficit/Hyperactivity Disorder (ADHD) in people aged 6 to 17, drug maker Shire Plc said Thursday.

Respirator Masks Best for Swine Flu Health Workers

September 03, 2009
Medical personnel should use them, but not the general public, experts say. Because people can catch the new H1N1 swine flu by inhaling the virus, health-care workers who deal with flu patients should wear properly fitted N95 disposable respirator masks, a new report from the Institute of Medicine advises.

These masks are not the same as loosely fitted surgical masks. N95 respirators fit tightly around the mouth and nose and have filters that can block about 95 percent of the flu virus, according to the report released Thursday.

Family, Friends Influence Breast Cancer Decisions

September 03, 2009
Patients' supporters often play role in treatment discussions, study finds. Family and friends don't just serve as emotional support for breast cancer patients, they also help patients decide which kind of surgery to have, a new study has found.

About three-quarters of patients surveyed brought a family member or friend to their first appointment with a surgeon, and the accompanying person exerted influence on the patient, the University of Michigan researchers noted.

In particular, women who had a friend or family member accompany them to the first appointment were more likely to receive a mastectomy, compared with women who went alone.

New Compound Shrinks Skin Cancers

September 02, 2009
Study found more than half of advanced basal cell carcinomas responded to treatment. An experimental cancer drug that switches off the so-called "Hedgehog" pathway beat back tumors in more than half of patients with advanced basal cell carcinoma, a type of skin cancer.

The drug also helped a 26-year-old man suffering from medulloblastoma, the most common form of brain cancer in children.

"We were both pleased and surprised.

Pancreatic Cancer Deaths Higher for Blacks

September 02, 2009
Accounting for risk factors made no difference in disparity, researchers find. Blacks have a significantly higher risk of dying from pancreatic cancer than whites, a new U.S. study has found.

Keep Your Flu Shots Straight This Fall

September 02, 2009
What you need to know about vaccinations for swine flu, regular flu. This fall, Americans will face a double challenge in getting shots for two strains of flu .

Swine Flu May Be Less Dangerous Than Predicted

Study

September 01, 2009
Researchers challenge 'superbug theory' in animal tests using three flu strains. Fears that the H1N1 swine flu will turn into a "superbug" this year may be unfounded, say researchers at the University of Maryland.

In laboratory tests, the virus responsible for the swine flu pandemic did not take a virulent turn when combined with other strains of seasonal flu. But it did spread more rapidly than the other viruses, confirming the need for swine flu vaccinations, the researchers said.

Blood Test May Spot Pancreatic Cancer Early

September 01, 2009
Researchers hope to detect the disease while it is still treatable. Texas scientists say they have found small molecules in the blood that can spot pancreatic cancer, a finding that could have diagnostic implications in the future.

Levels of these molecules, called microRNAs, are elevated in patients suffering from pancreatic cancer, the fourth-leading cancer killer in the United States. The disease usually isn't diagnosed until it is in an advanced stage, when treatment is all but ineffective, the researchers say.

Adult Weight Gain Tied to Prostate Cancer Risk

September 01, 2009
White men risk more aggressive tumors if pounds mount up in 20s, 30s, study finds. Men who pack on excess pounds as young adults are at heightened risk of developing prostate cancer, although the risk varies by ethnic group, researchers from the University of Hawaii report.

Obesity is a risk factor for many common cancers, including colorectal cancer and breast cancer in postmenopausal women. However, whether obesity plays a role in prostate cancer risk has been unclear, researchers say.

New Therapy Spares Organ in Early Esophageal Cancer

September 01, 2009
Less invasive procedure shaves off lesions, preserves esophagus, researchers say. Early-stage cancers of the esophagus can be treated effectively by less invasive, organ-sparing endoscopic therapy, a new study has found.

This is good news, as esophageal cancer arising from Barrett's esophagus is increasing in frequency faster than any other cancer in the United States, and 90 percent of patients die within five years of being diagnosed, according to a news release from the Mayo Clinic.

Esophageal cancer is diagnosed in its early stages about 20 percent of the time, Dr.

Blood Thinner May Prevent Chemo-Related Clots

September 01, 2009
Daily injection cut risk in half for Italian study patients. Cancer patients who receive chemotherapy are more likely to develop blood clots than other people, but now a new study says a blood-thinning drug could cut the risk in half.

Besides posing a significant risk of problems in the heart, brain and lungs, blood clots are especially difficult to treat in cancer patients and can lead to interruptions in chemotherapy. They can also greatly increase costs in patients who already face high expenses, the researchers noted in their study published online Aug.

Chemotherapy Linked to Sleep-Wake Cycle Disruptions

September 01, 2009
Biological clock out of sync in patients being treated for breast cancer, study finds. New research suggests that chemotherapy in breast cancer patients disrupts cycles of sleep and wakefulness, and continued treatment leads to worse and more lasting problems.

In the study, researchers recruited 95 women with breast cancer who were scheduled to receive chemotherapy. Their average age was 51.

Swine Flu on Campuses Boosts Call for Vaccinations

September 01, 2009
Officials expect return of virus that first surfaced last spring. As clusters of H1N1 swine flu break out on U.S. college campuses, school administrators are beefing up efforts to encourage students to take preventative steps to keep the virus from spreading further.

Prostate Cancer Over-Diagnosed

Study

September 01, 2009
The result is over-treatment for many men, researchers say. Mass screening for prostate cancer with a test for prostate-specific antigen (PSA) has led to mass over-diagnosis and over-treatment, a new study contends.

Since the PSA screening test came into use in 1986, federal government data show that the number of prostate cancer cases in the United States has risen substantially, said the report in the Aug. 31 online issue of the Journal of the National Cancer Institute.

Harm Begins With a Few Cigarettes, a Little Smog

August 31, 2009
Levels of toxins in air don't have to be high to be hazardous, studies find. Even a little bit of poison in the air .

Exposure to Tobacco Smoke Before Birth Affects DNA

August 31, 2009
Cigarettes may trigger prenatal gene changes, leading to lifelong health problems, study suggests. Women who smoke while pregnant increase their unborn child's long-term risk for health problems, including childhood asthma, cardiovascular disease and lower pulmonary function, and a new study may help experts understand why.
Researchers at the Keck School of Medicine of the University of Southern California (USC) found that maternal smoking actually changes the unborn child's DNA patterns.
The new study found that fetal exposure to maternal smoking was linked to differences in DNA methylation, an epigenetic mechanism.

Valcyte Approved for Cytomegalovirus in Children

August 31, 2009
A leading cause of infection in transplant patients The U.S. Food and Drug Administration has approved Valcyte (valganciclovir hydrochloride) to prevent cytomegalovirus (CMV) disease in children 4 months to 16 years who are undergoing kidney or heart transplant, Swiss drug maker Roche said Monday.

New Robotic Arm Has Softer Surgical Touch

August 31, 2009
Device helps find tumors during minimally invasive surgery, researchers say. A robotic surgical arm that can gently "feel" for cancerous tumors during minimally invasive surgery has been developed by Canadian scientists.

The device, invented at the University of Western Ontario and at Canadian Surgical Technologies and Advanced Robotics, will help surgeons better isolate tumors from softer surrounding tissue and, it is hoped, improve cancer survival rates, according to the study published in the September issue of the International Journal of Robotics Research.

During an operation, surgeons often use their hands to palpate (or gently feel) for tumors, which tend to have a different texture from healthy tissue and can shift in the body after a CT scan and other pre-surgical imaging tests.

Genetic Clues May Lead to New Skin Cancer Therapies

August 31, 2009
Mutant genes linked to melanoma could be targets for treatment, researchers say. Scientists have isolated a group of genetic mutations involved in the growth of melanoma, the deadliest form of skin cancer. Their work may lead to therapies with existing drugs that target the same mutations.

Led by Yardena Samuels of the National Human Genome Research Institute, the research team from the U.

Study Details Swine Flu Transmission Rates

August 28, 2009
Every infected person puts 1.5 other people at risk, researchers say. Every person who is infected with the H1N1 swine flu puts 1.5 other people at risk over the three days before coughing, fever and other symptoms appear.

That's the conclusion of a new study published in the journal Influenza and Other Respiratory Viruses.

Meat, Dairy Won't Up Odds for Breast Cancer

August 28, 2009
Two studies find no clear link; other research supports fiber to ward off the disease. An adult woman's intake of meat, eggs and dairy products should not boost her risk for breast cancer, new research shows.

For years, dietary factors have been debated as either boosting or reducing the risk of breast cancer, with research yielding conflicting results. But in the new research, scientists could not conclude that meat, eggs or dairy product intake as an adult raised breast cancer risk.

Zenpep Approved for Pancreatic Disorder

August 28, 2009
Makes up for lack of digestive enzymes The U.S. Food and Drug Administration has approved Zenpep (pancrelipase) delayed-release capsules to treat a pancreatic disorder that prevents people from properly digesting food, Dutch drug maker Eurand NV said.

Whole Grains, Bran May Fight Hypertension in Men

August 28, 2009
New findings replicate similar data for women, experts say. Men, want to keep high blood pressure at bay? Try reaching for whole grains.

That's the message from a Harvard study that found that whole grain foods and foods high in bran bring a boost to heart health. Although this study is among men, data from the Women's Health Study found similar results, the researchers say.

Scans Shed New Light on Concussions

August 28, 2009
Technology helps detect hidden brain damage, study shows. Researchers say they've discovered a new way to detect evidence of brain damage after concussions, potentially paving the way toward more effective treatments for head injuries.

By detecting damage from concussions early with the help of the latest brain scanning technology, doctors could begin cognitive rehabilitation treatment and prevent complications, study author Dr. Michael Lipton, an associate director of the Gruss Magnetic Resonance Research Center at Albert Einstein College of Medicine of Yeshiva University, explained in a university news release.

Colon Cancer Stopped in Its Tracks in Swiss Study

August 28, 2009
Gene-based treatment could block tumors, prevent recurrence, researchers say. Swiss scientists report that they may have found a way to stop colon cancer in its tracks by tinkering with a genetic pathway that allows cells to communicate with one another.

The treatment potentially could help prevent colon cancer from reaching advanced stages and moving to other organs.

The research, published Aug.

Kristi Yamaguchi, Olympic Ice Skater, Pushes Seasonal Flu Shots

August 28, 2009
She reminds public there's more than swine flu circulating out there. Olympic gold medal figure skater Kristi Yamaguchi is teaming up with U.S. health experts to deliver a simple and important message as flu season approaches: With all the hype around the H1N1 swine flu, don't forget to get a shot against the seasonal flu.

Steady Improvements Seen for Young Blood Cancer Patients

August 27, 2009
Survival has significantly increased, research shows. American teens and young adults newly diagnosed with blood-related cancers now live longer than they did in the 1980s, new research has found.

Researchers analyzed data from the Surveillance, Epidemiology and End Results (SEER) database, a population-based cancer registry in the United States. They compared data from 1981-1985 with data from 2001-2005 and found significant improvements in survival for patients with five blood-related cancers.

U.S. Childhood Vaccine Rates Good But Could Be Better

CDC

August 27, 2009
Compliance still high and stable, but more coverage needed among poor, report finds. More than three-quarters of U.S. children have received the recommended vaccinations, but greater efforts are needed to reach youngsters who are not fully immunized, a U.

Another Report Finds Swine Flu Targeting the Young

August 27, 2009
But health experts emphasize that most infections are relatively benign. As U.S. health officials brace for the expected return of the H1N1 swine flu this fall, much of the focus has been on children and young adults, who seem particularly vulnerable to the newly identified virus.

Get Ready for Gruesome Cigarette Warnings

August 27, 2009
Graphic images of diseased body parts could become the norm on packaging. Would a gruesome picture of a cancer-ravaged mouth with rotting teeth make you think twice about buying a pack of cigarettes?

That's the goal of new federal regulations expected to go into effect within three years. The rules will require tobacco companies to cover at least half of the front and back of packages with graphic .

Gene 'Fix' in Egg Prevents Inherited Diseases in Monkeys

August 26, 2009
But the technique is bound to be controversial if tried in humans, experts warn. A genetic tweak of the unfertilized eggs of macaque monkeys effectively prevented the transmission of diseases typically passed down through the maternal line, U.S. scientists reported.

Advice Helps Prevent Pain After Breast Cancer Surgery

August 26, 2009
Patients benefit from information on how to reduce risk of lymphedema, experts say. Patients recovering from breast cancer surgery have a greater chance of avoiding a painful and debilitating post-surgery condition if they get a little extra information, a study has found.

Lymphedema is a condition that causes a debilitating swelling of the extremities following breast cancer surgery. Symptoms also include pain, fatigue, numbness and reduced limb mobility.

Blood Flow Mismatch Seen in Pancreatic Cancers

August 26, 2009
Findings may help explain why many patients respond poorly to chemo and radiation. Finnish researchers say they have identified a blood-flow metabolism mismatch that predicts pancreatic cancer aggressiveness.

The investigators used a three-dimensional imaging technique called positron emission tomography (PET) to measure blood flow and glucose consumption .

Women's Exercise Priorities Vary With Life Stages

August 26, 2009
Self-care often loses out to family obligations, analysis finds. The amount of exercise women get changes as they go through different life phases, according to Australian researchers.

In an analysis of data from more than 40,000 women, lower levels of physical activity were associated with marriage and childbirth in young women and declining health in older women. But, the researchers found, activity levels often increased in women who were retired or widowed.

Many Health-Care Workers May Shun Swine Flu Shot

August 26, 2009
Hong Kong study finds some fear side effects, question benefits. Despite fears of an impending swine flu pandemic this fall and winter, more than half of all health-care workers surveyed in Hong Kong said they will not get vaccinated.

Their reason: fear of possible side effects and doubts about the vaccine's efficacy, according to Chinese research reported online Aug. 26 by the journal BMJ.

Sen. Edward M. Kennedy Dies at 77

August 26, 2009
Diagnosed with brain tumor last year, his relentless optimism, new therapies helped him exceed expectations, experts say. Sen. Edward M. Kennedy, the last surviving brother in a unique American political dynasty and one of the most influential senators in history, died late Tuesday night at his summer home on Cape Cod after a 15-month battle with brain cancer.

Tobacco Use Kills 6 Million People Annually

Report

August 25, 2009
And costs the global economy $500 billion each year. Tobacco use kills an estimated six million people worldwide each year and drains $500 billion annually from the global economy in lost productivity, misused resources, and premature deaths.

That assessment comes from The Tobacco Atlas, Third Edition, published by the American Cancer Society and the World Lung Foundation and released Tuesday at the LIVESTRONG Global Cancer Summit in Dublin, Ireland.

What's more, illnesses and deaths from tobacco use are totally preventable through such "well-established public policies" as tobacco taxes, advertising bans, smoke-free public places, and health warnings on packages, the report said.

More Women Surviving After Early Breast Cancer

August 25, 2009
Still too little is known about these 'in situ' malignancies, experts say. The first accounting of women with breast cancer in situ in the United States finds that in 2005 there were 610,171 survivors, but that by 2016 that number is expected to increase to more than 1 million.

Breast cancer in situ now accounts for 20 percent of newly diagnosed breast cancers. It is the early stage of the disease, when it is still confined to the layer of cells in the ducts or lobules of the breasts.

HPV Vaccine Could Prevent Many Penile Cancers

August 25, 2009
Nearly half of the tumors are caused by strains covered by the shot, study finds. The human papillomavirus (HPV) causes about half of penile cancer cases in the world, and giving vaccines to males could greatly reduce the incidence of the disease, a new study suggests.

Penile cancer remains rare, accounting for less than 1 percent of adult male cancers in North America and Europe, but that rate jumps to as high as 10 percent in Africa and Asia, according to Spanish researchers reporting online Aug. 25 in the Journal of Clinical Pathology.

Hormone Therapy for Early Prostate Cancer Not Always Best

August 25, 2009
Study finds treatment raises death risk in those who also have heart disease. Men who have been diagnosed with prostate cancer and who also have underlying heart disease may not benefit from treatment with hormones, new research suggests.

In fact, such hormone therapy may actually increase their odds of dying.

"For men who've had a prior heart attack or heart failure, use of hormone therapy for prostate cancer was associated with a shortened lifespan," said study author Dr.

International Travel Raises Risk of Typhoid

August 25, 2009
Drug-resistant strains most common among visitors to Indian subcontinent, CDC reports. International travel is the most common cause of infection with an antimicrobial-resistant strain of typhoid fever among patients in the United States, a new study finds.

About 300 cases of typhoid fever are reported in the United States each year, and the majority of these cases are associated with foreign travel, especially to India, Pakistan and Bangladesh. Over the last 20 years, the emergence of Salmonella serotype Typhi strains resistant to antimicrobial drugs has complicated the treatment of patients in the United States, according to researchers at the U.

Tamoxifen May Up Risk of Second, More Aggressive Breast Cancer

August 25, 2009
But survivors shouldn't stop taking the anti-cancer drug, experts say. The drug tamoxifen is a tried-and-true way to lower the chances of developing the most common type of recurrence among breast cancer survivors, but new research suggests it raises the risk of getting a more aggressive cancer in the healthy breast by more than four times.

However, the finding is no reason to ditch the anti-cancer drug, as even the lead researcher emphasized.

"All treatments have risks and benefits," said study author Dr.

Saliva May Help Spot Oral Cancer Early

August 25, 2009
Study suggests potential for a non-invasive diagnostic test. In a major step towards early diagnosis of oral cancer, researchers have found that saliva contains at least 50 microRNAs that could aid detection.

In the study, U.S.

Xyzal Approved for Younger Kids

August 25, 2009
Antihistamine sanctioned for children as young as 6 months The antihistamine Xyzal (levocetirizine dihydrochloride) has been approved for children aged six months and older for indoor allergies and hives, drug makers UCB and Sanofi-Aventis said.

The medication, available as a liquid or pill, had been approved previously for people aged six years and older. The expanded approval also sanctions the drug's use to treat outdoor allergies in children aged two years and older.

FDA Investigating Weight-Loss Drug Over Reports of Liver Damage

August 25, 2009
32 cases have been reported since orlistat came on market in 1999 As U.S. health officials announced Monday that they are investigating the weight-loss drug orlistat for possible incidents of liver damage, experts noted the drug might not even work well enough to warrant such potential risks.

Protein May Identify Deadlier Breast Cancer

August 25, 2009
Findings might help doctors determine prognosis, researchers say. A protein linked to more aggressive and advanced breast cancer tumors has been identified by German researchers.

The investigators analyzed 229 breast tissue samples from patients with cancer and compared them with healthy breast tissue. The study found that patients whose tumors had elevated levels of GLI1 (glioma-associated oncogene homolog 1) protein tended to have a more advanced stage of cancer, had an increased number of cancerous lymph nodes and a greater chance of death.

Smokers' Cars Loaded With Nicotine

August 25, 2009
Levels twice those found in restaurants and bars that permit smoking, study suggests. Passengers riding in the cars of smokers are exposed to nicotine levels nearly twice those found in restaurants and bars that permit smoking, a new study suggests.

The dangers of exposure to secondhand smoke are well known, including the risk for heart and respiratory disease, and have led to laws banning smoking in many public places. Many anti-smoking advocates believe the next frontier in the fight against secondhand smoke is in cars.

Testosterone Therapy May Help Men With Heart Failure

August 24, 2009
Injections of male hormone boosted cardiac performance in Italian study. Injections of the male hormone testosterone increased blood-pumping ability and heart muscle strength in men with heart failure, Italian researchers report.

"From our study, it appears that testosterone supplementation is useful for both patients with low and normal testosterone levels, although the improvements are greater in those with low levels," said Dr. Ferdinando Iellamo, an assistant professor of internal medicine at the University of Rome Tor Vergata, and lead author of a report in the Sept.

MRI Might Find Early Alzheimer's

August 24, 2009
Detection could help slow down the disease, study says. The brains of people in the very early stages of Alzheimer's disease might become hyperactive to compensate for disease-related deterioration, a new study suggests.

Researchers from the Cleveland Clinic tested 69 mentally healthy adults, two-thirds of whom were at risk for Alzheimer's disease because of family history or genetic markers. Functional MRI was used to monitor the participants' brains as they were asked if they recognized the names of famous celebrities and unfamiliar people.

Marital Separation May Hurt Cancer Survival

August 24, 2009
Married and never-married did the best a decade later, study shows. When it comes to surviving cancer, separation from your spouse appears to be worse for your health than divorce or even widowhood, a new study suggests.

In contrast, being married .

Not Everyone Wants to Be Vaccinated Against Pandemic Flu

August 24, 2009
But personal hygiene prevention methods are not enough, experts warn. Some people may refuse to get vaccinated against a pandemic virus if they believe the risks outweigh the benefits, suggests a new study.

Canadian researchers conducted 11 focus groups in Vancouver before the start of the current swine flu pandemic. Participants were asked how willing they'd be to receive a new vaccine in the event of a pandemic.

Going Back to School With Asthma Takes Extra Work

August 22, 2009
Lung association recommends flu shots, check-ups and communication with school staff. There are a number of ways that parents of children with asthma can prepare for flu season and the new school year, says the American Lung Association.

"Good hygiene is the best and first line of defense against any type of cold or flu. This includes frequent handwashing and covering your mouth when coughing or sneezing," Dr.

Obesity Tied to Prostate Cancer Recurrence

August 21, 2009
Leads to poor prognosis in both blacks and whites after surgery, study finds. Obesity increases the risk of prostate cancer recurrence in both black and white men, says a U.S. study that challenges previous research suggesting obesity may be more significant for black men.

Swine Flu Vaccine Seems Safe in Early Trials

August 21, 2009
No worrisome side effects so far, U.S. officials say; flu infections continue to be mild. As the H1N1 swine flu virus continues to circle the globe, producing minor infections similar to seasonal flu, U.S. health officials said Friday that they were on track for a viable vaccine by the fall, with early indications that the shot is safe.

Sabril Approved for Infantile Spasms

August 21, 2009
In children ages 1 month to 2 years Sabril (vigabatrin) Oral Solution has been approved by the U.S. Food and Drug Administration to treat infantile spasms in children aged 1 month to 2 years, the agency said Friday in a news release.

Medication Review May Help With Heart Failure

August 21, 2009
Hospitalizations decline when doctors, pharmacists collaborate, study finds. If doctors and pharmacists work together to ensure that people with heart failure take their medicines correctly, hospitalizations would be less frequent, an Australian study suggests.

In a study of 5,717 people with heart failure, the hospitalization rate for the 273 who had their medications reviewed by doctors and pharmacists was 45 percent lower than the hospitalization rate for the others, whose medicines did not undergo a collaborative review.

People in the study averaged about 82 years old.

Depression's Effect on Pleasure Is Real

August 21, 2009
Using scans, researchers spot changes in the way the brain responds to music. Loss of interest in previously enjoyable activities is a common sign of depression .

Swine Flu May Not Close College Classrooms

CDC

August 20, 2009
Unless situation becomes severe, simple steps could reduce outbreak's impact, agency says. Unless the swine flu outbreak this fall is worse than expected, U.S. colleges and other post-secondary education centers may not need to cancel classes, federal health officials said in a new advisory issued Thursday.

School Kids, Parents Should Get Flu Vaccines First

August 20, 2009
Study shows targeting 'super-spreaders' protects most vulnerable in end. The best way to stop the spread of flu, be it the seasonal flu or swine flu, is to vaccinate those most likely to spread the virus, namely school children and their parents, new research suggests.

These recommendations run counter to those of the U.S.

Better Pap Smear Follow-Up Needed Among Lower-Income Women

August 20, 2009
Disparities seen in screening rates, appropriate care in Canadian study. In the Canadian province of Ontario, fewer than half of women with abnormal Pap tests receive proper follow-up care and low-income women are less likely to be screened for cervical cancer than high-income women, a new study has found.

"Cervical cancer is one of the most preventable forms of cancer, yet in Ontario more than 1 million women have not been screened, and a disproportionate number of these women are living in lower-income communities," principal investigator Dr. Arlene Bierman, a physician at St.

New Hib Vaccine Granted Accelerated Approval

August 20, 2009
To help remedy vaccine shortage Accelerated approval for Hiberix, a Haemophilus b Conjugate Vaccine, has been granted by the U.S. Food and Drug Administration, drug maker GlaxoSmithKline said.

Swine Flu Vaccine Delay Manageable, Experts Say

August 20, 2009
Having 45 million doses by Oct. 15 will still be useful, they stress. Health experts do not believe that the delay in receiving swine flu vaccine will thwart the U.S. government's strategy to protect Americans against the newly circulating virus.

Scientists Spot How Sugar 'Feeds' Tumors

August 20, 2009
Finding could lead to new cancer treatments, researchers say. New information about how sugar "feeds" tumors has been uncovered by U.S. researchers, who said the finding may also have implications for other diseases such as diabetes.

Gene Mutation Improves Response to Lung Cancer Drug

August 19, 2009
Finding supports worthiness of genetic screening. People with lung cancer who are screened for a genetic mutation and then given a drug called Tarceva, which is believed to work well with that mutation, live longer than those without the mutation who take the drug, new research has found.

According to the Spanish authors of a study in the Aug. 20 issue of the New England Journal of Medicine, this type of widespread screening is actually doable and could lead to better decisions about treatment.

Newer Drug Beats Tamoxifen for Older Breast Cancer Patients

August 19, 2009
Letrozole boosted survival and should be first-line treatment, experts say. For postmenopausal women with breast cancer, treatment with the drug letrozole (Femara) increases survival after surgery more than the widely used tamoxifen, a new study confirms.

Both letrozole and tamoxifen have been used to prevent recurrence of breast cancer in postmenopausal women with hormone receptor-positive cancer, but whether one drug is better than the other has been unclear. The new study compared the impact of the newer drug, letrozole, to tamoxifen.

Life Expectancy in U.S. Hits a New High

August 19, 2009
Deaths also at an all-time low, new government report shows. Life expectancy in the United States has reached almost 78 years, a record high, federal health officials said Wednesday.

Not only has life expectancy increased, but the death rate has dropped to an all-time low of 760.3 deaths per 100,000 people, according to the new report from the U.

Are Candles Making You Sick?

August 19, 2009
Researchers warn of toxic buildup from paraffin, suggest beeswax instead. Paraffin wax candles, used mainly for romantic ambiance, fragrance and light, may also contribute to air pollution inside your home.

The candles, which are made from petroleum, are a source of known human carcinogens and indoor pollution, researchers said in a study to be presented Wednesday at the American Chemical Society's national meeting in Washington, D.C.

Businesses Need Swine Flu Action Plan, U.S. Says

August 19, 2009
Employers must prepare now for more sick workers, new federal guidelines say. Telecommuting, flexible work hours and even keeping employees 6 feet apart are all ways to reduce the spread and impact of H1N1 swine flu on America's businesses, government experts said in new guidelines issued Wednesday.

Above all, employers need to remain flexible as the fall/winter flu season approaches, because the extent and severity of the outbreak remains uncertain, according to the guidelines for businesses issued by the U.S.

Patch 'Shots' May Someday Replace Injections

August 19, 2009
Microneedles could deliver meds safely and painlessly, researchers say. A skin patch lined with "microneedles" may someday offer a painless alternative to hypodermic needles, according to scientists working on the concept.

The technique could make flu shots a thing of the past, and treatment of diseases such as diabetes safer and more effective, the researchers said. Their work was to be presented Aug.

Treatment May Limit Graft-Versus-Host Disease

August 19, 2009
Problem in stem-cell transplants is common when donor, recipient are not related. People who need a blood stem-cell transplant may be able to lessen the chances that the transplanted material will attack the body .

Cervical Cancer Vaccine Seems Safe

August 18, 2009
Fainting most common adverse event with Gardasil, study finds. The vaccine that protects against human papillomavirus (HPV), a cause of cervical cancer, appears safe, with relatively few serious side effects, according to a new U.S. government study.

Estrogen Plays Surprise Role in Breast Cancer Treatment

August 18, 2009
Study finds it may slow disease if anti-estrogen therapies stop working. Researchers report that the paradoxical strategy of treating breast cancers that have become resistant to anti-estrogen therapies with estrogen actually shrank some tumors.

Not only that, but the estrogen made some of the tumors sensitive to anti-estrogen drugs once again.

The findings, reported in the Aug.

Chemo Plus Palliative Care Reaps Benefits

August 18, 2009
For those with advanced cancer, teaching self-management and empowerment improves quality of life. Providing palliative care at the same time that advanced cancer patients are undergoing treatment improves their quality of life and mood, a new study shows.

It included 322 patients randomly selected to receive either usual cancer care or a palliative care program consisting of four weekly educational sessions followed by monthly sessions until they died or the study ended. The palliative program was designed to encourage patient self-management and empowerment.

New Target Eyed for Colon Cancer Drugs

August 18, 2009
In mouse study, researchers see possibility of 'potent therapy' Drugs that target a cell surface molecule called ERBB3 could offer a more effective way to treat colon cancer, a new study suggests.

Currently, drugs that target the epidermal growth factor receptor (EGFR) are used to treat a number of cancers, but these drugs haven't proven very effective against colon cancer. ERBB3 is closely related to EGFR.

Video Gamers Older Than You Think

August 18, 2009
Also more out-of-shape and maybe depressed, new U.S. survey of Internet players finds The average video gamer is not the stereotypical adolescent locked to a computer screen 24/7. The real players, according to a new U.S.

Ibuprofen Rated Best for Pain of Broken Arms

August 18, 2009
Study finds kids don't do as well when given acetaminophen with codeine. For a child with a broken arm, ibuprofen is as effective at treating pain as acetaminophen with codeine, U.S. researchers report.

New Drug Approved for Gaucher Disease

August 18, 2009
An inherited metabolic disorder A new drug can be used to treat patients with a rare genetic disorder called Gaucher disease before the drug gets full marketing approval, according to the U.S. Food and Drug Administration.

Abnormal Protein May Signal Pancreatic Cancer

August 18, 2009
'Prion' could become diagnostic tool, researcher says Prion, an abnormal protein, is a biomarker of early pancreatic cancer, a new study suggests.

Prion accumulation causes mad cow disease, but very little is known about prions outside of the brain. This study identified the mechanism by which prions cause pancreatic tumors to grow more aggressively, said researchers at Case Western Reserve University School of Medicine in Cleveland.

Blood Pressure Drug Might Work Against MS

August 17, 2009
Research shows inflammation link between two disorders. Dr. Lawrence Steinman has this seemingly crazy idea that a drug commonly used to combat high blood pressure can help prevent the damage done to nerve cells in multiple sclerosis.

But people in the know tend to listen carefully to the ideas of Steinman, a professor of neurology at Stanford University, because one of his ideas was crucial in the development of natalizumab (Tysabri), a now widely used medication that can reduce the incidence of relapses in multiple sclerosis (MS) by two-thirds.

Antioxidants Pose No Melanoma Threat

August 17, 2009
Despite earlier study, new report finds no risk from common vitamin and mineral supplements. Vitamins C, E and other antioxidants do not increase the risk for melanoma, the most serious form of skin cancer, a new study found.

A recent study had suggested that the risk for melanoma was increased four-fold among women who took supplemental vitamins C and E, beta carotene, selenium and zinc. Because 48 to 55 percent of U.

Smoking Worsens Multiple Sclerosis

August 17, 2009
Raised risk of brain lesions and shrinkage, researchers found. Patients with multiple sclerosis who smoke appear to be at higher risk for the brain lesions linked with the disease and for brain shrinkage, new research suggests.

"Our study is showing that MS is more destructive as seen on MRI in smokers than nonsmokers," said study co-author Dr. Bianca Weinstock-Guttman, director of the Baird MS Center and Pediatric MS Center of Excellence at the State University of New York at Buffalo.

Pain Level May Predict Survival in Certain Cancer Patients

August 17, 2009
Discomfort should be monitored in those with head and neck malignancies, researchers say. Higher levels of post-treatment pain in head and neck cancer patients appear to be associated with lower survival rates, U.S. researchers have found.

Synthetic Protein Thwarts HIV Infection in Lab

August 17, 2009
By blocking cellular interaction, researchers say they can prevent disease production. Researchers report they were able to block HIV infections in the lab with synthetic proteins that prevented the virus from entering healthy cells.

In the study, researchers developed synthetic molecules that interfered with the ability of a key HIV protein called gp41 to interact with proteins in host cells.

By interrupting the interaction, HIV could not infect the cells, according to the study that appears online Aug.

Extavia Approved for Multiple Sclerosis

August 17, 2009
A type of interferon Extavia (interferon beta-1b) has been approved by the U.S. Food and Drug Administration to treat multiple sclerosis, drug maker Novartis said Monday.

Chewing Tobacco No Safer Than Smoking

August 17, 2009
New study adds to list of carcinogens harming those with smokeless habit. Tobacco users who think it's safer to dip snuff or chew tobacco than smoke are dead wrong, researchers say.

A study has found that taking one pinch of smokeless tobacco delivers the same amount of polycyclic aromatic hydrocarbons (PAHs) as smoking five cigarettes.

PAHs are common environmental contaminants that are formed as a result of incomplete burning of wood, coal, fatty meat or organic matter, according to information in a news release from the American Chemical Society.

Genetic Discovery May Improve Hepatitis C Treatment

August 17, 2009
Finding will help predict patient response to therapy, researchers say. The first biomarker that predicts a patient's response to hepatitis C treatments has been identified by U.S. researchers.

International Travel Health Guidebook Gets Updated

August 15, 2009
New CDC Yellow Book includes information on medical tourism and exotic destinations. If you are an international traveler, the U.S. government has a guidebook that could save your life.

Sex Hormone Levels Linked to Fractures in Men

August 14, 2009
Testing for estradiol, testosterone and SHBG could predict those at risk, expert says. Sex hormone levels affect the risk of broken bones in older men, says a new study.

The finding comes from a study that included 1,436 men age 65 and older who had their sex hormone levels measured periodically for about five years. The researchers found that men with low levels of estradiol or high levels of sex hormone binding globulin (SHBG) were more likely to suffer osteoporotic fractures.

Wine May Shield Breast Cancer Patients From Radiation Side Effects

August 14, 2009
Italian study suggests its natural antioxidants protect the skin. A glass of wine a day cut the risk of treatment-linked skin toxicity by two-thirds in women undergoing radiation therapy for breast cancer, Italian researchers report.

Skin reactions are a common side effect of cancer radiation therapy, and, while medications can help prevent these problems, they can be expensive and often have their own side effects. In some cases, drugs used to reduce radiation-linked side effects can actually protect breast cancer tumor cells, according to a news release from the American Society for Radiation Oncology.

Saphris Approved for Schizophrenia and Bipolar Disorder

August 14, 2009
Two severe psychiatric illnesses The drug Saphris (asenapine) has been approved by the U.S. Food and Drug Administration to treat adults with either schizophrenia or bipolar I disorder, the agency said Friday.

Get Smart About Swine Flu for Back-to-School

August 14, 2009
Simple steps can minimize the risk as fall looms, experts say. Students returning to school this year have another worry besides homework and lunchroom bullies: swine flu.

Experts say parents and kids need to act early and vigorously to reduce their risk of contracting the H1N1 virus.

"We do know that [the virus] is going to strike the school-age child and it's primarily because they're in crowded classrooms with lots of other children and have a better chance of spreading germs," said Sharon A.

Compound Targets, Destroys Cancer Stem Cells in Mice

August 13, 2009
Therapeutic possibilities are uncertain, researchers say. Researchers have identified a chemical able to seek out and destroy the stem cells that scientists believe give rise to cancer recurrence after treatment.

A growing body of research is showing that cancer stem cells play a role in cancer metastasis and in causing cancer to reappear even after treatment seems to have eradicated the initial tumor.

"Evidence is accumulating rapidly that cancer stem cells are responsible for the aggressive powers of many tumors," including breast, prostate, lung and others, said study author Robert Weinberg, a member of the Whitehead Institute for Biomedical Research at Massachusetts Institute of Technology.

It's Time for More Moms to Breast-Feed, U.S. Officials Say

August 13, 2009
Experts note rates are too low when benefits are so high. With breast-feeding rates still not at the levels health-care providers and policymakers would like, two U.S. health agencies have decided it's time to take action.

Exercise May Help in Leukemia Recovery

August 13, 2009
Small study finds physical activity reduces depression and fatigue. Exercise helps improve symptoms of fatigue and depression experienced by leukemia patients who are undergoing treatment, a new study shows.

It included 10 people who did individualized exercise sessions while in the hospital for the three to five weeks of the induction phase of leukemia treatment. The sessions included aerobic and resistance exercises, core exercises and light stretches that were tailored to each person's fitness level and leukemia symptoms.

MRI May Not Improve Breast Cancer Outcome

August 13, 2009
But it does increase likelihood of extensive surgery, researchers say. The use of MRI before surgery to assess the extent of early breast cancer may do more harm than good, a new review shows.

The study authors said this use of MRI increases the likelihood that patients will have more extensive surgery instead of a conservative therapy, but that this more aggressive treatment doesn't lead to improved surgical care or patient outcomes.

"Overall, there is growing evidence that MRI does not improve surgical care, and it could be argued that it has a potentially harmful effect," wrote the American and Australian researchers.

Cancer Deaths Declining, Especially Among Young

August 13, 2009
Advances in treatment, prevention and detection behind progress, study finds Cancer death rates are declining, especially among younger people, new research shows.

And while cancer is poised to become the number one killer in the United States, topping heart disease, that is because deaths from heart disease have decreased faster than for cancer.

"Older Americans have only experienced decreased [cancer] mortality very recently, but younger Americans have been seeing benefits for a long time so, as a result, everyone born in the last 60 years has been reaping the benefits of efforts in prevention research and treatment research and early detection research," said Dr.

Weight Lifting Can Ease Arm Swelling in Breast Cancer Survivors

August 12, 2009
Finding runs counter to standard advice doctors have given for years. Lifting weights can help prevent flare-ups of lymphedema, a painful swelling of the arm that often occurs after breast cancer surgery, new research shows.

The finding runs counter to what women have been told for years .

Stray Breast Cancer Cells Yield to Post-Op Chemo

August 12, 2009
Women with microscopic disease helped by additional treatment, research shows. Breast cancer patients with isolated tumor cells or tiny "micrometastases" in the lymph nodes benefit from adjuvant treatment, such as post-surgical chemotherapy or hormonal therapy, a new study finds.

Until now, many doctors doubted that the presence of micrometastases or isolated tumor cells affected long-term recovery, said Dr. Vivianne Tjan-Heijnen, head of the division of medical oncology at Maastricht University Medical Center in the Netherlands, the lead author of the study.

FDA Details Access to 'Investigational' Drugs

August 12, 2009
Goal is to help patients who might benefit from experimental medications. By clarifying rules governing patient access to so-called investigational drugs, U.S. health officials said Wednesday that they hope to expand the number of people who might benefit from these not-yet-approved medications.

When It Comes to Casual Sex, Men Aren't So Picky

August 12, 2009
Women place greater emphasis on good looks, study finds. Men are much more likely to seek and have casual sex than women, and are far less choosy about the looks of their sex partners.

That's the conclusion of a new study by British researchers who analyzed questionnaire responses from 860 American, German and Italian students.

The students were asked to imagine being approached by a member of the opposite sex, described as either "slightly unattractive," "moderately attractive" or "exceptionally attractive.

Scientists Reverse Multiple Sclerosis in Mice

August 12, 2009
Experimental treatment suppresses immune cells, forcing remission, study says. An experimental treatment that suppresses the immune system to put multiple sclerosis into remission completely reversed the disease in mice, Canadian scientists say.

In MS, the immune system attacks the central nervous system. The new treatment, called GIFT15, is composed of two proteins, GSM-CSF and interleukin-15, that are fused in the lab.

New Antibiotics May Target Cancer-Causing Proteins

August 12, 2009
Anti-cancer use of thiazoles could be possible, research suggests. Scientists are closer to understanding how a recently approved class of antibiotics may work against cancer.

The drugs, called thiazole antibiotics, appear to block a cellular protein called FoxM1, one of the most over-produced proteins in cancer cells, according to researchers at the University of Illinois at Chicago College of Medicine. FoxM1 is believed to play an important role in causing cells to become cancerous and may present a promising target for future anti-cancer treatments.