Twenty-five Articles match your search

'Lab on a Chip' Might Speed Breast Cancer Monitoring

October 07, 2009
Device makes measuring estrogen faster and simpler, researchers say. A pocket-size device under development could soon help monitor how well breast cancer treatments are working and help assess breast cancer risk by measuring levels of the hormone estrogen.

''We've developed a 'lab on a chip,' which is useful for making quantitative measurements of estrogen in samples of blood or tissue," said Aaron Wheeler, the Canada research chair of bioanalytical chemistry at the University of Toronto and a co-author of a report on the device in the Oct. 7 issue of Science Translational Medicine.

Estrogen Plays Surprise Role in Breast Cancer Treatment

August 18, 2009
Study finds it may slow disease if anti-estrogen therapies stop working. Researchers report that the paradoxical strategy of treating breast cancers that have become resistant to anti-estrogen therapies with estrogen actually shrank some tumors.

Not only that, but the estrogen made some of the tumors sensitive to anti-estrogen drugs once again.

The findings, reported in the Aug.

Studies Report More Harmful Effects From BPA

June 10, 2009
Chemical in plastics may hurt heart and fertility, researchers say. More potentially harmful health effects have been discovered for the chemical bisphenol A, found in clear plastic bottles and other everyday items, according to several new animal studies.

Not only are humans probably being exposed to generally unsafe levels of BPA, as the chemical is commonly called, but it could be causing arrhythmias, or irregular heartbeats, research shows. That could be especially problematic for women, who may be at higher risk for this type of cardiac threat.

Estrogen May Help Men's Hearts

May 12, 2009
Too much or too little of the hormone, though, can be damaging, study finds. Estrogen has long been implicated as being heart protective in premenopausal women, and a new study suggests that having just the right amount of estrogen might be helpful for men as well.

The study, in the May 13 issue of the Journal of the American Medical Association, found that men with heart failure who had the lowest levels of estrogen had about four times the risk of dying as men with average levels and that men with the highest levels of estrogen had more than twice the risk of dying as men with average levels of the hormone.

"Among men with chronic heart failure and reduced left-ventricular ejection fraction, high and low concentrations of estradiol [estrogen] compared with the middle quintile of estradiol are related to an increased mortality," the researchers wrote.

Lowered HRT Use May Have Cut Heart Attacks

April 24, 2009
But women didn't experience a similar drop in strokes, study finds. The decline in the use of hormone replacement therapy (HRT) to treat menopause symptoms has been mirrored by a drop in the rate of heart attacks among American women, a new study finds.

But there's been no decrease in the rate of strokes, researchers noted.

Hormone replacement therapy was widely used to treat menopause symptoms until 2002, when researchers published a study that said HRT increased the risk of heart attack.

Female Hormones Deter Salt-Sensitive Hypertension

February 06, 2009
Estrogen appears to improve kidneys' ability to shed sodium, study says. Hormones and a cell receptor in the kidneys may explain why premenopausal women have fewer problems than men with salt-sensitive hypertension, a new study says.

Salt-sensitive hypertension occurs when the kidneys hold onto more sodium than necessary. This drives up blood pressure as the body tries to force the kidneys to get rid of excess salt.

HRT Shrinks the Brain

January 12, 2009
But research shows it does not damage cerebral blood vessels in older women. Two studies looking at the same group of women found that while hormone therapy is linked with brain shrinkage, it does not seem to be associated with early signs of cerebrovascular disease.

This suggests that hormone therapy's effect on brain volume, not its effect on the brain lesions that indicate "silent strokes," is the mechanism by which hormones increase the risk for dementia in women over 65.

"These are a nice companion to cognitive studies reported earlier.

Obesity Linked to Ovarian Cancer

January 05, 2009
Excess estrogen may contribute to malignancy, study suggests. Obese postmenopausal women who have never used hormone replacement therapy may face an increased risk of ovarian cancer, compared to normal-weight women, a new study suggests.

Interestingly, obese women who have used hormone replacement therapy (HRT) for symptoms of menopause may not face increased risk for this type of malignancy.

The study findings are published in the Feb.

Hormones Boost Frequency of Women's Migraine With Aura

December 22, 2008
Mouse study finds 2 genes likely behind spread of depression with these headaches. In women, hormones increase the frequency of an inherited form of severe migraine accompanied by visual disturbances called auras, according to a Massachusetts General Hospital study.

Like other types of migraine, familial hemiplegic migraine affects women more than men. Most cases of familial hemiplegic migraine are caused by mutations in the CACNA1A gene.

Migraine Might Lower Breast Cancer Risk

November 06, 2008

Lower estrogen levels among sufferers may be the reason why, researchers say. Women who experience migraines may actually have a 30 percent lower risk of developing breast cancer, say researchers from the Fred Hutchinson Cancer Research Center in Seattle.

Testosterone Patch Restores Libido in Postmenopausal Women

November 05, 2008

But, the male hormone therapy may cause unwanted hair growth, study finds. There aren't a lot of treatment options for older women with flagging libidos, but a new study suggests that a testosterone patch may significantly improve the number of satisfying sexual episodes that women experience.

Excess Weight Seems to Boost Breast Cancer Risk

November 02, 2008

Exercising 30 to 60 minutes a day may offer needed protection, experts say. Obesity can wreck a person's health for many reasons. But for women, too much weight tacks on an additional danger: Studies have linked obesity and breast cancer in a variety of ways.

Aerobics Can Reverse Mental Decline in Older Adults

October 16, 2008

Review of studies shows workouts that leave a person breathless boost brain tissue volume. Regular exercise can reverse age-related brain decline, according to a U.S. cognitive neuroscientist.

Drug Re-Sensitizes Breast Tumors to Treatment

September 05, 2008

Phase II study finds sorafenib helps reverse disease resistance to anti-hormonal therapy. The drug sorafenib may help "re-sensitize" certain breast cancer tumors to anti-hormonal drugs, Georgetown University Medical Center researchers say.

Postmenopausal Women With Breast Cancer Face Joint Issues

August 12, 2008

Obesity, previous HRT, chemo also raised chances for those on endocrine treatment, study says. Postmenopausal women with breast cancer who are receiving endocrine treatment may be at increased risk of joint issues, including arthritis, a new study finds.

New Molecule Discovery Shows Promise Against Tamoxifen-Resistant Breast Cancers

June 16, 2008
Potential therapy could be the next generation of treatments, researchers say.

Bone Drug Lowers Risk of Breast Cancer Recurrence

June 02, 2008
Zometa, used to treat osteoporosis, showed no unanticipated side effects, researchers report.

Older Women Have Harder Time Preserving Muscle Than Men

March 26, 2008
Key difference appears to be how their bodies react to protein, study says.

HRT Raises Recurrence Risk Among Breast Cancer Survivors

March 25, 2008
Trial was halted early after risk of both recurrence and new malignancies surfaced.

Estrogen Levels in Blood Predict Breast Cancer's Return

March 06, 2008
Study found women who had a recurrence had twice as much of the hormone in their system.

Woman's Hips Might Indicate Daughter's Breast Cancer Risk

October 08, 2007
Wider hips mean more estrogen, bringing higher odds for the illness, researchers say.

Most Women Unaware of Hormone Replacement Study

September 21, 2007
Only 29% recall trial that cast doubt on supplemental estrogen's safety, study finds.

Flaxseed May Relieve Hot Flashes

August 31, 2007
Small Mayo Clinic pilot study shows 50% reduction over 6 weeks

Estrogen May Have Preventive Role in Women's Schizophrenia

August 04, 2008

The estrogen estradiol, when combined with antipsychotic drugs, may help relieve psychotic symptoms in women with schizophrenia, an Australian study suggests. The women's psychotic symptoms, including delusions and hallucinatory behavior, were assessed weekly, and those taking estradiol showed a greater improvement in symptoms.

Progesterone Won't Shield Women Against Alzheimer's

Mouse study shows no benefit for the female hormone

June 02, 2008
There's no evidence that progesterone -- which is often given with estrogen in hormone replacement therapy -- offers women any protection against Alzheimer's disease, U.S. researchers say.
They conducted tests on female mice genetically engineered to develop an Alzheimer's-like disease to come to this conclusion.
The study appears in this week's issue of the Journal of Neuroscience.


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