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Too Few Older Adults Get Recommended Screenings
Prepared by the U.S.
Task Force Member Defends Mammography Guidelines
Dr. Timothy Wilt, a member of the U.
Mammography
What to Do Now?
Guidelines Delay Start of Mammograms to Age 50, Then Every Other Year
Also, breast self-exams, which women have been urged to do routinely, have not helped lower the death rate from breast cancer, the guidelines add.
Not all agree with the revised recommendations, however.
Gene Linked to Breast Cancer Might Boost Heart Health
The study, performed in mice, also found that when this gene, called BRCA1, is turned off, it promotes an inflammation that can lead to atherosclerosis or hardening of the arteries.
Although there has been no previous observation of increased cardiovascular death specifically in the large number of people who carry the BRCA1 mutation, there has been a surprising suggestion of higher non-cancer death in this population, noted study senior author Dr.
Lab Study Slows Breast Cancer Spread to Bone in Mice
The drug .
Less HRT, Fewer Cases of Possible Breast Cancer Precursor
This is the first time a link has been found between atypical ductal hyperplasia .
Breast Cancer May Be Gone, But Pain Lingers
The research, published in the Nov. 11 issue of the Journal of the American Medical Association, strengthens earlier findings, said study senior author Dr.
Breast Cancer Drugs May Fight Cervical Cancer, Too
The drugs also cleared precancerous growths in the cervix and vagina, and prevented the onset of cancer in mice with precancerous lesions.
The breast cancer drug fulvestrant and the breast cancer/osteoporosis drug raloxifene were given to mice genetically engineered to carry human papillomavirus (HPV) 16, which is strongly associated with cervical cancer.
Dense Breasts Raise Risk of Cancer Recurrence
Breast density has already been linked with an increased risk of developing breast cancer, and experts have suspected that very dense breasts may also be associated with an increased risk of cancer recurrence at the site of the original cancer after lumpectomy.
The Canadian study, which involved a 10-year follow-up and is published online Nov.
Shorter, More Intense Radiation OK for Some Breast Cancers
"This concept of a shorter length of treatment is gaining acceptance," said Dr. Manjeet Chadha, associate chair of radiation oncology at Beth Israel Medical Center and associate professor of radiation oncology at Albert Einstein College of Medicine, both in New York City.
Drug Could Help Treat Small HER2-Positive Breast Tumors
Two studies, from the United States and Italy, examined cases of women with small (1 centimeter or less in diameter) HER2-positive breast cancers that hadn't spread to the lymph nodes. The researchers found that the cancer is more than two times more likely to recur in HER2-positive women than in women with HER2-negative breast cancers.
Meditation May Reduce Stress in Breast Cancer Patients
The two-year trial included 130 patients at Saint Joseph Hospital in Chicago, aged 55 and older, randomly assigned to either a transcendental meditation group or to a usual care control group. Quality of life was assessed every six months.
Mapping the Link Between Alcohol, Cancer
The findings could have meaning for the prevention and treatment of cancer, which has been linked to alcohol use in some cases. In particular, scientists suspect that alcohol is connected to colon and breast cancer, although it's not known exactly how.
Breast Abnormality Follow-Up Often Later in Black Women
American Cancer Society Stands By Cancer Screening Guidelines
"We are not redoing or rethinking our guidelines at this time, nor are we going to restate our guidelines to emphasize the inadequacies of screening," said Dr. Len Lichtenfeld, deputy chief medical officer of the American Cancer Society.
Breast Cancer Gene Tied to Diagnosis at Younger Age
The finding, presented at the 2009 Breast Cancer Symposium, held last week in San Francisco, could potentially affect how women are screened for breast cancer.
About 5 percent to 10 percent of breast cancer cases are thought to be connected to a genetic mutation that's also linked to ovarian cancer.
Race Not a Factor if Breast Cancer Chemo Succeeds
Having no sign of the disease is considered a good sign that bodes well for a woman's prognosis, although it's not a guarantee that the cancer has vanished for good, the study authors noted.
"Our findings confirm [that having no sign of the disease] is a strong prognostic indicator and a surrogate for good survival, despite a patient's race, and that it's vital we continue to strive towards achieving this milestone for all women with breast cancer," said study co-author Dr.
Mastectomy Not First Choice for Most Breast Cancer Patients
The survey, reported in the Oct. 14 issue of the Journal of the American Medical Association, also found that U.
With Hormone Therapy, Tender Breasts May Signal Cancer Risk
Women taking estrogen plus progestin who reported developing breast tenderness after starting the hormone therapy were 48 percent more likely to develop invasive breast cancer than women on hormone therapy who did not experience breast tenderness.
Researchers said more study is needed before they would recommend that women who experience this symptom discontinue taking the hormones.
'Lab on a Chip' Might Speed Breast Cancer Monitoring
''We've developed a 'lab on a chip,' which is useful for making quantitative measurements of estrogen in samples of blood or tissue," said Aaron Wheeler, the Canada research chair of bioanalytical chemistry at the University of Toronto and a co-author of a report on the device in the Oct. 7 issue of Science Translational Medicine.
Gene Test Might Predict Tamoxifen's Effectiveness
The findings, which appear in the Oct. 7 issue of the Journal of the American Medical Association, could allow clinicians to predict which women will benefit most from the drug, which has been the gold standard of breast cancer care for the past 25 years.
New Test Assesses Individual Breast Cancer Risk
In the Oct. 5 online issue of the Journal of Clinical Oncology, researchers report that the more acini a woman has .
Breast Cancer Death Rates Continue to Drop 2% Annually
Deaths from breast cancer have dropped more than 2 percent each year since 1990. And in the past decade that decline in deaths has been shared by black, Hispanic and white women.
Social Isolation Adversely Affects Breast Cancer
Social isolation can actually change the expression of genes important in the growth of mammary gland tumors, according to Dr. Suzanne D.
More Women Having Other Breast Removed
But there's little evidence to suggest that this practice is actually beneficial in terms of improving survival, say the authors of a study published Sept. 28 in Cancer.
After-Effects of Chemotherapy May Include Memory Problems
Many cancer patients who receive chemotherapy report "chemobrain" .
Timing, Type of HRT May Determine Breast Cancer Risk
Overall, starting estrogen-progestagen therapy soon after menopause appears to boost the risk of breast cancer, even when only used for short periods of time, according to the study, which was published in the Sept. 14 online issue of the Journal of Clinical Oncology.
For Hispanics, a Unique Cancer Profile Emerges
At first glance, Hispanics' lower death rate from cancer seems to be good news, but one explanation is that the Hispanic population skews younger than the general U.S.
Medications That Lower Breast Cancer Risk Carry Other Dangers
That was the conclusion of researchers who looked at numerous published studies, including randomized clinical trials and a head-to-head assessment of the medications used for risk reduction. Those include tamoxifen, raloxifene and tibolone.
Common Diabetes Drug May Fight Cancer
In lab tests using mice with breast cancer, researchers found that the drug combination suppressed the cancer stem cells thought to drive tumor progression.
"We discovered that metformin selectively kills cancer stem cells.
Routine Testing Would Improve Herceptin Use in Breast Cancer
Under current guidelines, women with breast cancer in its early stages should receive tests to see if Herceptin might be appropriate for them.
Scientists Spot Key to Breast Cancer Spread
In a study at the University of Texas M.D.
Scientists Spot Clue to Cancer's Aggressiveness
Family, Friends Influence Breast Cancer Decisions
About three-quarters of patients surveyed brought a family member or friend to their first appointment with a surgeon, and the accompanying person exerted influence on the patient, the University of Michigan researchers noted.
In particular, women who had a friend or family member accompany them to the first appointment were more likely to receive a mastectomy, compared with women who went alone.
Chemotherapy Linked to Sleep-Wake Cycle Disruptions
In the study, researchers recruited 95 women with breast cancer who were scheduled to receive chemotherapy. Their average age was 51.
Meat, Dairy Won't Up Odds for Breast Cancer
For years, dietary factors have been debated as either boosting or reducing the risk of breast cancer, with research yielding conflicting results. But in the new research, scientists could not conclude that meat, eggs or dairy product intake as an adult raised breast cancer risk.
Advice Helps Prevent Pain After Breast Cancer Surgery
Lymphedema is a condition that causes a debilitating swelling of the extremities following breast cancer surgery. Symptoms also include pain, fatigue, numbness and reduced limb mobility.
More Women Surviving After Early Breast Cancer
Breast cancer in situ now accounts for 20 percent of newly diagnosed breast cancers. It is the early stage of the disease, when it is still confined to the layer of cells in the ducts or lobules of the breasts.
Tamoxifen May Up Risk of Second, More Aggressive Breast Cancer
However, the finding is no reason to ditch the anti-cancer drug, as even the lead researcher emphasized.
"All treatments have risks and benefits," said study author Dr.
Protein May Identify Deadlier Breast Cancer
The investigators analyzed 229 breast tissue samples from patients with cancer and compared them with healthy breast tissue. The study found that patients whose tumors had elevated levels of GLI1 (glioma-associated oncogene homolog 1) protein tended to have a more advanced stage of cancer, had an increased number of cancerous lymph nodes and a greater chance of death.
Newer Drug Beats Tamoxifen for Older Breast Cancer Patients
Both letrozole and tamoxifen have been used to prevent recurrence of breast cancer in postmenopausal women with hormone receptor-positive cancer, but whether one drug is better than the other has been unclear. The new study compared the impact of the newer drug, letrozole, to tamoxifen.
Estrogen Plays Surprise Role in Breast Cancer Treatment
Not only that, but the estrogen made some of the tumors sensitive to anti-estrogen drugs once again.
The findings, reported in the Aug.
Wine May Shield Breast Cancer Patients From Radiation Side Effects
Skin reactions are a common side effect of cancer radiation therapy, and, while medications can help prevent these problems, they can be expensive and often have their own side effects. In some cases, drugs used to reduce radiation-linked side effects can actually protect breast cancer tumor cells, according to a news release from the American Society for Radiation Oncology.
MRI May Not Improve Breast Cancer Outcome
The study authors said this use of MRI increases the likelihood that patients will have more extensive surgery instead of a conservative therapy, but that this more aggressive treatment doesn't lead to improved surgical care or patient outcomes.
"Overall, there is growing evidence that MRI does not improve surgical care, and it could be argued that it has a potentially harmful effect," wrote the American and Australian researchers.
Cancer Deaths Declining, Especially Among Young
And while cancer is poised to become the number one killer in the United States, topping heart disease, that is because deaths from heart disease have decreased faster than for cancer.
"Older Americans have only experienced decreased [cancer] mortality very recently, but younger Americans have been seeing benefits for a long time so, as a result, everyone born in the last 60 years has been reaping the benefits of efforts in prevention research and treatment research and early detection research," said Dr.
Weight Lifting Can Ease Arm Swelling in Breast Cancer Survivors
The finding runs counter to what women have been told for years .
Stray Breast Cancer Cells Yield to Post-Op Chemo
Until now, many doctors doubted that the presence of micrometastases or isolated tumor cells affected long-term recovery, said Dr. Vivianne Tjan-Heijnen, head of the division of medical oncology at Maastricht University Medical Center in the Netherlands, the lead author of the study.
Breast-Feeding May Lower Breast Cancer Risk
"We saw a 59 percent lower risk of breast cancer among women with a family history who had ever breast-fed," stated Dr. Alison Stuebe, lead author of a study appearing in the Aug.
In U.S., No Comeback Seen for Hormone Therapy
But those beliefs collapsed in 2002, when researchers pulled the plug three years early on the Women's Health Initiative, a large-scale, federally funded study of hormone replacement therapy (HRT).
Many Opt for Surgery to Lower Breast, Ovarian Cancer Risk
Their study included 211 women, aged 35 to 45, with BRCA1 or BRCA2 gene mutations, which are known to increase the risk of breast and ovarian cancer. The women found out about their increased risk after undergoing genetic testing.
Living in U.S. May Raise Hispanics' Cancer Risk
Living the American lifestyle is probably to blame, say researchers from the University of Miami Miller School of Medicine.
Of three Hispanic subgroups they studied .
Periodic Dieting May Cut Breast Cancer Risk
Three sets of mice predisposed to developing breast tumors were put on different diets: unlimited eating, intermittently cutting calories by 25 percent, or permanently reducing caloric intake 25 percent. Those on the intermittent diet fared best, with only 9 percent developing mammary tumors compared to 35 percent of those chronically restricted and 71 percent of those that ate all they wanted.
Breast CT Scanner Could Improve Cancer Screen Comfort
"Breast CT is superior to mammography for [detecting] masses," said John Boone, vice chair of research radiology at the University of California Davis. He presented information about the potential of breast CT for treatment this week at the American Association of Physicists in Medicine meeting, in Anaheim, Calif.
Breast Cancer Drug May Beat Fungal Infection
University of Rochester Medical Center researchers found that tamoxifen kills yeast in mice with Candida infections, which can be fatal to people with compromised immune systems, including people with cancer or HIV and those taking immunosuppressants for chronic conditions.
At extremely high levels, tamoxifen slashed yeast levels by 150-fold, causing most fungus cells to break up and die while halting surviving cells from progressing into a disease-causing state, their study found.
Culture May Help Raise Breast Cancer Death Rate for American Indians
The findings are significant, because breast cancer ranks second on the list of cancer-related deaths in American Indian and Alaskan native women, and these women also have the lowest five-year survival rate when compared with other ethnic groups.
University of California-Davis and community researchers found cultural and tribal issues have an impact on the fight against cancer.
Elevated Insulin Levels Linked to Breast Cancer
Researchers at Albert Einstein College of Medicine of Yeshiva University in New York City found a strong association between elevated insulin levels in the blood and increased risk of breast cancer. Their findings were published online in the International Journal of Cancer.
New Gene May Signal Aggressive Breast Cancer
Using a new method of analyzing "microarray expression profiles" of breast cancer tumors, researchers from the Genome Institute of Singapore determined that the gene RCP might be implicated in the development of breast cancer.
They then studied noncancerous, human breast epithelial cells and found that when RCP protein was overproduced, the otherwise healthy cells began to look more like tumor cells, according to the study in the July 20 issue of the Journal of Clinical Investigation.
Spiritual Outlook Can Affect Mental Health in Breast Cancer
The study included 198 women with early-stage breast cancer and 86 women with late-stage breast cancer, who were recruited from hospitals in western Pennsylvania. The women were interviewed at the start of the study and again eight to 12 months later.
Reminders Boost Mammography Appointments
More Mammograms May Mean More 'Harmless' Cancers
The report of a so-called overdiagnosis rate of 35 percent came from an examination of breast cancer screening programs in five countries conducted by Danish researchers and published online Thursday in BMJ.
The finding echoes those of a study published late last year that concluded that some breast cancers may naturally disappear without treatment.
Migraines Linked to Reduced Breast Cancer Risk
And, no matter what a woman's age or what migraine triggers a woman might be avoiding, the risk of breast cancer is still reduced, according to the study, which appears in the July issue of Cancer Epidemiology, Biomarkers & Prevention.
"In this study, we evaluated the relationship between migraine and breast cancer risk and found that women who have migraine have a 26 percent lower risk of breast cancer than women without a history of migraine," said study author Dr.
New Clues to Race Gap in Breast Cancer Outcomes
For a quarter of a century, researchers have been aware of the so-called race gap in certain cancers. The racial disparity "first emerged about 25 years ago," said Idan Menashe, a postdoctoral fellow at the U.
Cancer Gap Between Whites, Blacks May Be Biological in Part
For many years, the disparity in racial survival was attributed to the fact that black cancer patients have less access to quality care, are diagnosed when their cancer is in later stages, and don't receive the same standard of care as white patients.
But this analysis of almost 20,000 patient records from the Southwest Oncology Group's database of 35 clinical trials found no statistical difference in survival based on race for several other cancers .
Research Reveals Clues to Breast Cancer's Spread
Metabolic Syndrome May Make Breast Cancer More Likely
Metabolic syndrome, also known as insulin resistance syndrome, consists of a cluster of such conditions as abdominal obesity, high blood glucose levels, impaired glucose tolerance, abnormal lipid levels and hypertension.
The study included 4,888 women, ages 50 to 79, who did not have diabetes at the start of the study and were periodically tested for components of metabolic syndrome over eight years as part of their participation in the Women's Health Initiative study.
Breast Cancer Numbers Dip Most in Wealthy, Urban Areas
Researchers at the Northern California Cancer Center studied national breast cancer incidence data for the years 1997 to 2004 to compare rates in rural and urban areas and poor and rich areas of the country.
"Between 2001 and 2004, incidence rates of invasive breast cancer declined more than 8 percent in the United States," study leader Christina Clarke said in a news release.
New Cancer Drug Fights Tumors in Those With BRCA Mutations
Women who carry BRCA1 and BRCA2 gene mutations are susceptible to developing breast and ovarian cancer, and among men these mutations are related to an increased risk for prostate cancer, the British researchers noted.
Olaparib works differently than other cancer drugs in that it blocks Poly(ADP-ribose) polymerase (PARP), a protein involved in DNA repair.
Schizophrenia Linked to Higher Risk of Dying From Cancer
Researchers from the University of Reims in France found that people with schizophrenia die from cancer at four times the rate of the general population, making it the leading cause of death in that group after suicide. The study, published online June 22 in Cancer, recommended that doctors pay closer attention to cancer prevention and early detection in people with that crippling psychiatric disorder.
Gene Can Dampen Chemo Drug Effectiveness
Scientists at the U.S.
Cancer Diagnosis May Tax Physical, Mental Health
Bryce B. Reeve of the U.
Grilled Meats Not Tied to Breast Cancer in Older Women
Previous studies looking at whether eating meat and increased breast cancer risk might be linked have yielded inconsistent results.
In the new study, researchers at Albert Einstein College of Medicine of Yeshiva University analyzed data on 120,755 older American women, including the types of food the women ate, how often they ate certain foods and how they prepared their meat.
Pausing Hormone Therapy Doesn't Cut Mammogram Recalls
"Postmenopausal hormones make breasts denser .
Research Finds 'New Crop' of Breast Cancer Genes
Their study, published online in this week's issue of the Proceedings of the National Academy of Science, found that the AGTR1 gene makes healthy breast cells act like cancer cells. But tests on mice with tumors containing the gene found that the blood pressure drug losartan (Cozaar) stopped that behavior and shrank the tumors by 30 percent within eight weeks of treatment, according to the researchers, from the University of Michigan Comprehensive Cancer Center.
'Micro' Spreading of Breast Cancer Needs Treating, Study Urges
That's because leaving these cancers untreated appears to result in a higher rate of cancer recurrence, according to a new study.
Skipping additional treatment for the tiny metastases, known as micrometastases or micromets, could actually result in more deaths, said the study's lead author, Dr.
New Insights, Inroads Against Breast, Ovarian Cancers
Newton-John, 60, spoke at a special news briefing on advances and insights in breast and gynecologic cancers, part of the American Society of Clinical Oncology (ASCO) annual meeting in Orlando, Fla.
Some Antidepressants May Thwart Tamoxifen's Effect on Breast Cancer
The finding was presented this weekend at the American Society of Clinical Oncology's annual meeting, in Orlando, Fla.
But to muddy the waters further, a second study found that the antidepressants did not impair tamoxifen's cancer-fighting powers.
U.S. Cancer Death Rates Continue to Fall
The American Cancer Society's Cancer Statistics 2009 report finds an encouraging 19.2 percent drop in cancer death rates among men from 1990 to 2005, as well as an 11.
Drug May Extend Life When Breast Cancer Spreads
When compared with Taxotere, Abraxane extended the time before a recurrence by almost seven months, effectively doubling survival. Both are members of a class of drugs known as taxanes.
New Research Sheds Light on Breast Cancer Prognosis
Low levels of caveolin-1, which plays a role in how cells absorb things, in the stromal cells were linked to a poor patient outcome in a study by Dr. Agnieszka K.
Many Black Women Refuse Breast Cancer Treatments
Black women have almost twice the rate of advanced breast cancer as white women do, largely because the disease is often diagnosed after it has already progressed. In addition, some black women have misconceptions about cancer and are reluctant to seek medical help, the researchers said.
Stem Cell Study Offers Hope for Targeting Tumors
Stem cells carrying TNF-related apoptosis-inducing ligand (TRAIL) destroyed lung, squamous, breast and cervical cancer cells in laboratory cultures, according to British researchers. When tried on mice, the specialized cells shrunk subcutaneous breast tumors by about 80 percent, and when injected intravenously, they helped destroy about 38 percent of metastasized lung tumors in rodents.
Poor Women Seem to Be Skipping Breast Cancer Drugs
Those who do not follow instructions to take these drugs, medications that block hormones, face a higher risk of dying, said study author Dr. Gretchen Kimmick.
Ginger Eases Nausea From Chemo
"Ginger at a daily dose of 0.5-to-1 gram significantly aids in the reduction of chemotherapy-related nausea on the first day of chemotherapy, and reduced nausea will lead to improved quality of life in many cancer patients," said study author Julie Ryan, an assistant professor of dermatology and radiation oncology at the James P.
Chemotherapy Superior to New Drug for Early Breast Cancer
"After three years, 85 percent of people who received chemotherapy were doing well, and 68 percent of people who received capecitabine were doing well," said lead researcher Dr. Hyman Muss, a professor of medicine at the University of North Carolina at Chapel Hill.
Healthy Behaviors Slow Functional Decline After Cancer
The study participants included 641 people in the United States, Canada and the United Kingdom, aged 65 to 91, who were overweight and were long-term (five years or more) survivors of breast, prostate and colorectal cancer. Some were assigned to a control group, while others were assigned to a 12-month intervention program that included telephone counseling, mailed materials promoting exercise, improved diet, and modest weight loss.
Where You Live May Affect Your Cancer Diagnosis
A study of residents of Illinois finds that city dwellers are more likely to have doctors spot breast, colorectal, lung or prostate cancer later in the disease's progression than their peers residing in the suburbs or rural areas. The rates for these late-stage cancers were highest in Chicago, the most densely populated and urban of the areas in the analysis, and tapered off the more rural and sparse an area's population became, according to the findings, which were based on a review of the 1998 to 2002 Illinois State Cancer Registry.
Genes Linked to Spread of Breast Cancer
Breast Self-Exam Rates Go Up With Counseling
Young Women's Breast Tissue Offers Clues to Cancer Risk
The study of 400 women, ages 15 to 39, and their mothers found that breast tissue composition in young women may be associated with their risk for breast cancer in middle age and older.
"It is known that the breast is most susceptible to the effects of carcinogens at early ages.
Minorities to Bear Brunt of Rise in U.S. Cancer Cases
Rates of new cancer diagnosis are expected to jump by 45 percent among the population generally and by 67 percent among people aged 65 or older. New cancer cases are predicted to double among minorities, experts say.
Gene Alteration May Affect Breast Cancer Therapy
They found that women with tumors that carried topoisomerase II alpha (TOP2A) gene alterations had 65 percent better relapse-free survival and 67 percent better overall survival when treated with an anthracycline-containing regimen (cyclophosphamide, epirubicin and 5-fluorouracil [CEF]) than when treated with a non-anthracycline-containing regimen (cyclophosphamide, methotrexate and 5-fluorouracil [CMF]).
Women whose tumors were TOP2A-normal, however, had a similar response to both therapies.
Drug May Help Against Inflammatory Breast Cancer
Inflammatory breast cancer accounts for up to 6 percent of all invasive breast tumors in the United States and western Europe, according to the researchers. Symptoms include rapid onset of swelling, redness of breast skin, a pitted appearance caused by fluid under the skin of more than two-thirds of the breast, tenderness, hardening and warming of the breast.
No Verdict Yet on Grape Seed Extract vs. Breast Cancer
Because studies have suggested that grape seed extract inhibits aromatase, an enzyme that helps in estrogen production, the researchers looked at whether grape seed extract supplements could lower hormone levels in postmenopausal women.
What they found was a dramatic and sustained decrease in one patient with high baseline estrogen levels.
Soy May Not Lead to Denser Breasts
That's good news because it's believed that increased breast density is associated with a higher risk of breast cancer. A number of studies have suggested that dietary factors, including isoflavones (estrogen-like plant compounds) might increase breast density.
Walnuts May Help Keep Breast Cancer at Bay
One group of mice was fed a daily diet that included what would be equivalent to 2 ounces of walnuts in humans, while another group of mice ate a regular diet. The mice that ate the diet with walnuts had a much lower incidence of breast tumors, fewer glands with a tumor and smaller-sized tumors.
Study Rates Breast Cancer Risks Among Races
Researchers conducting on ongoing study have so far enrolled 1,826 white and 360 black women with breast cancer, and 1,766 healthy white and 240 healthy black women. The initial data shows that lack of physical activity and being overweight or obese are associated with a 20 percent increased risk of breast cancer in both groups of women.
Targeted Treatments Show Mettle Against Advanced Cancers
The findings, which were to be presented Sunday at the American Association for Cancer Research annual meeting, in Denver, fit into the current framework of "personalized" medicine, explained Dr. Minetta Liu, a translational researcher/breast oncologist at Georgetown University's Lombardi Comprehensive Cancer Center in Washington, D.
Dense Breasts Complicate Testing and Treatment
But now they're discovering how the density of a woman's breast tissue can also predict how she will respond to cancer treatment and whether her cancer will recur.
The denser a woman's breasts, the less fat they have, explained Diana Buist, an epidemiologist at Group Health Center for Health Studies in Seattle.
Harmless Virus May Be Deadly to Breast Cancer
"We suspected that reovirus might be effective against cancer stem cells, because we have shown time and again how well it destroys regular cancer cells," Dr. Patrick Lee, a cancer researcher at Dalhousie Medical School in Halifax, Nova Scotia, said in a news release.
Health Tip
Lumps in the Breast
Thankfully, an abnormal lump in the breast doesn't always mean breast cancer.
According to the University of Virginia Health System, a non-cancerous breast lump may result from:
A cyst, a small sac filled with fluid.
Yale Plans Closer Look at Exercise and Cancer
The U.S.
Scientists Identify More Breast Cancer Genes
Microsurgery May Cut Swelling After Breast Cancer Treatment
Lymphedema affects up to 30 percent of the women who have their lymph nodes removed or radiated as part of their breast cancer treatment, according to the National Cancer Institute. The swelling condition .
Black Women at Higher Risk for Aggressive Breast Tumors
Soy May Help Shield Asian-American Girls From Breast Cancer
When Breast Cancer Recurs, Finding Pre-Symptoms Is Key
The researchers looked at information on 1,044 women who were seen at a medical center in Florence, Italy, between 1980 and 2005 and who had developed a second breast cancer .
Lymphedema Raises Cost of Breast Cancer Care
Younger Women With Breast Cancer Face Added Peril
In analyzing treatment of 652 breast cancer patients over three decades, researchers from the University of Texas M.D.
Wine Color Won't Change Breast Cancer Risk
"If you choose to drink at all, choose your drink based upon what tastes good to you, because wine is not associated with a decreased risk of breast cancer, regardless of the type," said study author Polly Newcomb, program head of cancer prevention at the Fred Hutchinson Cancer Research Center in Seattle.
The findings were published in the March issue of Cancer Epidemiology, Biomarkers & Prevention.
Women With Breast Cancer Gene Favor Preventive Mastectomy
Several type of risk management strategies are available to women found to have a mutated BRCA1 or BRCA2 gene, which is known to elevate a woman's risk of breast cancer. These range from simply having more frequent screening exams to the preemptive removal of a breast.
New Test May Mean Faster Breast Cancer Treatment
Men With BRCA Gene Mutations Unaware of Cancer Risks
Yoga May Bring Calm to Breast Cancer Treatment
Drinking Raises Cancer Risk for Middle-Age Women
Waiting Is the Hardest Part in Biopsies
Women who are waiting for results after a breast biopsy experience abnormalities in the levels of a stress hormone known as cortisol, a fact that might not only be damaging to overall health but might compromise future treatment if, in fact, the results come back positive.
The findings, appearing in the March issue of Radiology, argue for faster relaying of results to patients.
Technique May Let More Women Use Tamoxifen
If successful, the technique might someday allow breast cancer patients who don't respond to tamoxifen to benefit from the drug.
"We're excited by the results," said study author Caroline Ford, a member of the department of cell and experimental pathology at Lund University in Malmo, Sweden.
Calcium Helps Ward Off Colon Cancer
Cancer Death Rates Decline Among Blacks, But Disparities Linger
However, they are still diagnosed at more advanced stages of cancer than whites, the report's authors note, and blacks have lower survival rates at each stage of diagnosis of most types of cancers.
There will be about 150,090 new cases of invasive cancer diagnosed in U.
One in Three Cancer Survivors on Unemployment Line
The meta-analysis of more than 20,000 cancer survivors found that 33.8 percent of those who'd battled cancer were out of work vs.
Menopause Drug Tied to Breast Cancer Recurrence
Tibolone, brand name Livial, isn't available in the United States but is approved in 90 countries for easing menopausal symptoms and approved in 55 countries as an osteoporosis treatment. Many breast cancer patients use the drug to counteract the effects of early menopause caused by cancer treatments.
Hodgkin's Survivors Prone to Breast Cancer Later
"We can cure most patients now who have Hodgkin's disease. Back in 1950, it was regarded as a universally fatal disease," said study co-author Dr.
Experts Release Guidelines on Use of Breast MRI
Pregnancy May Not Affect Breast Cancer Survival
Minorities Distrust Medical System More
Almost half of all women agreed that they had "sometimes been deceived or misled by health-care organizations." Eighteen percent strongly agreed with the statement.
Statins Don't Cut Cancer Risk
"We certainly didn't see any positive effects," said Ronald Lubet, program director in the division of cancer prevention at the National Cancer Institute. He led the study using mice and rats, which was published in the February issue of Cancer Prevention Research.
Two-Thirds of Hispanic Women Discover Breast Cancer Themselves
What's troubling, however, is that about half of all women who noticed an abnormality waited at least a month before seeking medical help, according to new research being presented at the American Association for Cancer Research Conference on the Science of Cancer Health Disparities, in Carefree, Ariz.
Two-thirds of breast cancers in Hispanic women are discovered by accident, while only 23 percent come to light through a mammography and another 6 percent through a clinical exam.
Drop in Breast Cancer Rates Due to Drop in HRT Use
2 Years of Hormone Use May Be 'Safe'
The finding follows a report last month from the Society of Obstetricians and Gynaecologists of Canada that women have been needlessly scared away from using hormone therapy during menopause.
Researchers for the U.
Fewer Women Are Having Mammograms
Childhood Cancer Survivors Not Getting Recommended Mammograms
The recommendation suggests starting screening mammograms at age 25, or 8 years after the last radiation treatment, whichever comes last. These guidelines are in place because women who've had chest radiation as children, teens or young adults have a significantly higher risk for breast cancer.
Why Cancer in One Breast May Affect the Other
The chances of developing cancer in a second breast, known as contralateral breast cancer, increases once a tumor has been found in one breast. And certain factors, such as a family history of breast cancer, further increase this risk, prompting some women to opt for preventative surgery.
Database Helps Assess Your Breast Cancer Risk
"Breast cancer is multifactorial. It would be rare for there to be a single environmental chemical that alone would be sufficient to cause an increase in breast cancer," said Dr.
More Americans Urged to Get Cancer Screenings
The rate of screening for breast and cervical cancers has stayed about the same since 2000, while the rate of colorectal cancer screening has increased but not as fast as experts had hoped, according to the report released Thursday by the American Cancer Society.
"More people need to get screened than are being screened, and they need to get screened regularly .
Ovary Removal Lowers Odds of Cancer in High-Risk Women
Researchers from the University of Pennsylvania School of Medicine and Memorial Sloan-Kettering Cancer Center did what's known as a meta-analysis, pooling the results of several studies and re-analyzing them. Led by Dr.
Garlic as a Cancer Fighter? Maybe Not
But a new review finds that the evidence linking garlic to a reduced risk for many cancers is not creditable and, for others, it is very limited.
"The public wants to believe that garlic may be effective in reducing the risk of cancer, but so far scientific evidence is limited to conclude [it works] for all types of cancers," said Dr.
Heart Drug May Be a Cancer Fighter
Cancer cells need to create new blood vessels to survive. But many of these cells are oxygen-deprived and need to switch on genes that produce a protein called hypoxia-inducible factor (HIF-1), which help cells survive in low-oxygen conditions.
Genes Predict Chances of Breast Cancer's Spread
Scientists from the National Cancer Institute (NCI), building upon earlier research, found in both mice and human breast tumor samples that a certain gene signature predicted the chance of metastasis. Many experts have believed that metastasis is primarily the result of non-inherited mutations in cancerous tissue.
Grape Seed Extract Kills Leukemia Cells in Lab
University of Kentucky researchers say they found that the extract activates JNK, a protein that regulates the cell-signaling pathway the leads to cell death, or apoptosis.
The findings appear in the Jan.
High Insulin May Boost Odds of Breast Cancer
And that might be the link between obesity and breast cancer, say researchers from the Albert Einstein College of Medicine in New York City. High insulin levels have already been associated with obesity.
Cancer Medicine Advances on Many Fronts
A new report from the American Society of Clinical Oncology (ASCO) details 12 "major" advances and 19 "notable advances" across the gamut of cancer prevention, screening, treatment and survival in the past year.
"These specific advances .
Marital Distress May Affect Breast Cancer Recovery
Phenols in Quality Olive Oil Suppress Breast Cancer Gene
Extra-virgin olive oil, which is produced by pressing olives without the use of heat or chemical treatments, contains phytochemicals that are otherwise lost in the refining process. The Spanish researchers separated extra-virgin olive oil into fractions and tested these against breast cancer cells in the lab.
'Mediterranean'-Style Diet Best for Blood Sugar Control
A new study found that a diet of "low-glycemic foods" .
New Genetic Analysis Might Boost Breast Cancer Care
University of California at San Diego scientists, working with Korean researchers, used bioinformatic algorithms to identify these subnetworks. They then mapped the gene activity to the many networks of signaling pathways and protein complexes that prior research had found in human cells.
Progress Made in Predicting Breast Cancer Risk
The scientists presented their data during a teleconference Friday at the annual San Antonio Breast Cancer Symposium in Texas.
Patients with breast cancer tumors known as HER2-positive, even those a centimeter or less in diameter, have a substantially increased risk for relapse, and additional treatment after surgery should be considered, said Dr.
HRT Users Who Get Breast Cancer Less Likely to Die
Why?
"Hormone therapy seems to give you a particular type of cancer that is easier to treat," explained study author Sarah F. Marshall, a senior statistician at the University of California Irvine.
Risk Info for Breast Cancer Patients Too Confusing
Doctors typically show breast cancer patients a bar chart, based on a standard risk-assessment tool, with four different post-surgery choices: hormonal therapy alone, chemotherapy alone, hormonal therapy and chemotherapy combined, or no treatment at all. In a study, published in the December issue of Cancer, just a little more than half of 1,619 women shown the same graph correctly understood which choice would best increase their chance of survival.
Osteoporosis Drug Seems to Shrink Breast Tumors
Encouraging findings on several different drugs were presented Thursday at the CTRC-AACR San Antonio Breast Cancer Symposium in Texas.
First in the line-up, the osteoporosis drug zoledronic acid (Zometa) appears to shrink breast tumors in patients who undergo chemotherapy.
Non-Hormonal Therapies Aid Breast Cancer Patients
So say Greek researchers who conducted a review of 128 clinical trials that included more than 26,000 women with the disease.
The review showed that use of anthracycline regimens led to a 22 percent relative risk reduction in overall death, compared with older single-agent chemotherapy.
Cancer to Surpass Heart Disease as World's Leading Killer
Unless new treatments are found, there could be 27 million people with cancer by 2030, and 17 million cancer deaths annually. And, there could be 75 million people living with cancer within five years after diagnosis, according to a new report, 2008 World Cancer Report, released Tuesday by the World Health Organization.
Scientists ID Protein Aiding Breast Cancer Spread
Glowing Substance Lights Up Cancer in Mice
The man-made compound, a combination of the breast cancer drug Herceptin and a fluorescent molecule called BODIPY, binds to the HER2 protein contained on the surface of some breast cancer cells. It only glows, or fluoresces, when inside living cells .
New Statistical Model Could Cut Needless Breast Biopsies
Latest Breast Imaging Techniques Offer New Views
Both tests .
More High-Risk Women Preempt Breast Cancer
By the time she found the third lump, she was 25 and had watched her grandmother die of breast cancer (after being diagnosed at 55) and her mother endure both chemotherapy and radiation after being diagnosed with the same disease and undergoing a full mastectomy at age 45.
Radioactive 'Seed' Rx Helps Women With Implants Fight Breast Cancer
"It's such a challenge to take care of these augmented women," said Dr.
Health Tip
Examining Your Breasts
U.S. Cancer Rate-Death Rate Combo Drops for 1st Time
The drop in cancer rates is mostly due to fewer cases of lung, prostate and colorectal cancer among men, and fewer cases of breast and colorectal cancer among women.
Weight Boosts Older Women's Breast Cancer Risk
The weight itself is to blame for the added risk, the researchers concluded.
Some Breast Cancers May Regress on Their Own
Latin Women More Likely to Be Unhappy With Breast Cancer Treatment Decisions
Spanish-speaking women need more culturally targeted information, study finds. Latina women are almost six times more likely than white women to report great dissatisfaction and regret about their choice of breast cancer treatment, a new report says.
Cancer Drug Ups Risk of Clots in Veins
Those on Avastin faced 33% increased risk of dangerous side effect. The widely used cancer drug Avastin appears to be associated with a greater risk of developing blood clots in the veins of patients with a variety of cancers.
Canola Oil Consumed During Pregnancy Lowers Breast Cancer Risk for Offspring
Mouse study found it was better than corn oil during gestation and lactation Women whose mothers consumed canola oil during pregnancy and breast-feeding may be less likely to develop breast cancer than those whose mothers consumed corn oil, a new study suggests.
Diet, Exercise May Modify Breast Cancer Risks
Combined, they produce more potent anti-disease effect in postmenopausal women, study says. Scientists believe they have found out why diet and exercise affect a women's chance of breast cancer after she's past menopause, a new study says.
Wealthy More Likely to Have Breast Reconstruction
Black women less likely than white women to have reconstruction after mastectomy. After a mastectomy, wealthier women are more likely to have immediate breast reconstruction than their poorer counterparts, Johns Hopkins University researchers report.
Family History Ups Breast Cancer Risk Even Without BRCA Gene
Unknown mutations may account for increased odds, researchers say. The risk of breast cancer for a woman with a strong family history is four times higher than that of the general population -- even if she does not carry one of the breast cancer-linked mutations of the BRCA gene, a new study finds.
Psychological Counseling Boosts Breast Cancer Outcomes
Interventions cut risk of recurrence, lengthened disease-free survival, study finds. Psychological counseling may improve the chances of survival for breast cancer patients, a new study says.
Scientists Unravel Mystery of Tamoxifen Resistance
Some breast tumors produce a protein that defeats the drug. As many as 35 percent of women who take tamoxifen to prevent the return of breast cancer do not respond to the drug -- and now scientists think they know why.
Calcium, Vitamin D Won't Prevent Breast Cancer
But findings apply to postmenopausal women only, counters editorial Although calcium and vitamin D may keep your bones strong, these vital nutrients don't appear to help postmenopausal women lower their risk of breast cancer.
Free Web Site Lists Breast Cancer Clinical Trials
Studies are taking place at more than 1,100 facilities across the U.S. A free online service that provides clinical trial information for women diagnosed or at risk for breast cancer was launched this week by the University of California, San Francisco, Center of Excellence for Breast Cancer Care.
Migraine Might Lower Breast Cancer Risk
Lower estrogen levels among sufferers may be the reason why, researchers say. Women who experience migraines may actually have a 30 percent lower risk of developing breast cancer, say researchers from the Fred Hutchinson Cancer Research Center in Seattle.
Folic Acid and Other B Vitamins Won't Help Prevent Cancer
Seven-year study of supplements found no change in disease risk Taking folic acid or other B vitamin supplements won't lower your risk of cancer, new research shows.
Excess Weight Seems to Boost Breast Cancer Risk
Exercising 30 to 60 minutes a day may offer needed protection, experts say. Obesity can wreck a person's health for many reasons. But for women, too much weight tacks on an additional danger: Studies have linked obesity and breast cancer in a variety of ways.
Vigorous Exercise Can Cut Breast Cancer Risk
But benefits only apply to normal-weight women, study says. Vigorous activity can reduce the risk of breast cancer by about 30 percent in normal-weight women, according to an 11-year U.S. study of 32,269 postmenopausal women.
Research Reveals Why Tamoxifen Doesn't Always Work
Receptors on the surface of breast cancer cells may be the key, scientists say. Scientists have uncovered new clues to how breast cancer cells become resistant to the widely-used prevention and treatment drug tamoxifen.
Hot Flashes, Night Sweats a Good Sign for Breast Cancer Patients
Symptoms correlated with lower recurrence rates, study finds. Hot flashes, night sweats and joint symptoms in breast cancer patients getting endocrine treatment are signs of estrogen depletion or blockage and may point to successful treatment, British researchers report.
Statins Lower Risk of Clots in Cancer Patients
3-D Doppler Ultrasound Helps ID Breast Cancers
Method detects masses with higher blood flow speeds, likely indicating disease, study says. Radiologists can now better distinguish malignant and benign breast masses by using three-dimensional power Doppler ultrasound, a new report says.
Mammograms Remain Best Way to Spot Breast Cancer
Friday is National Mammography Day. Mammograms detect 80 percent to 90 percent of breast cancers in women without symptoms, and all women 40 and older should get a yearly mammogram, says the American Cancer Society (ACS) as it marks National Mammography Day on Friday, Oct. 17.
Understanding the Benefits and Risks of Chemotherapy
Besides hair loss and nausea, side effects include fatigue, vomiting, mouth sores and pain. Women starting chemotherapy for breast cancer often expect unpleasant side effects, from hair loss to nausea.
Nicotine May Spur Breast Cancer's Spread
Early study suggests it pushes cells to migrate to distant sites. Nicotine may help push breast cancer cells from the original tumor to other parts of the body, contributing to the metastasis that so often kills patients.
Younger Breast Cancer Survivors Risk Disease in Other Breast
Study suggests link to radiation therapy, but experts say treatments are safer today. Young women receiving radiation after having surgery for breast cancer are at increased risk of developing a new tumor in the opposite -- or contralateral -- breast, a new Dutch study suggests.
Cancer Screenings for Medicaid Patients Miss Targets
Only about half receive recommended tests for colon, breast, cervical disease, study finds. Screening rates for colorectal, breast and cervical cancer among older Medicaid patients are below national objectives, a new study suggests.
Caffeine Consumption Doesn't Raise Overall Breast Cancer Risk
Large study did discover link with benign breast disease, or when tumor was larger. Drinking coffee or consuming other caffeine-laden foods does not appear to boost breast cancer risk, new research indicates.
Tamoxifen Cuts Fracture Risk
Study
But the benefit disappears when breast cancer drug is stopped. Tamoxifen, the drug used for more than 30 years to treat breast cancer, reduces the risk of osteoporosis-related fractures, a new study shows.
NSAIDs Might Lower Breast Cancer Risk
Analysis of 38 studies found painkillers showed protective effect. Non-steroidal anti-inflammatory drugs (NSAIDs) are associated with a reduced risk for breast cancer, a new review suggests.
Tamoxifen Speeds Diagnosis of ER-Negative Breast Cancer
Study suggests the drug may make tumors easier to spot. A treatment that helps prevent one type of breast cancer in women with an evaluated risk of the disease also appears to help doctors make an earlier diagnosis of another form of breast cancer, a new study reports.
Urine Samples Could Reveal Breast Cancer Risk
High levels of two biomarkers might indicate early tumor growth, study suggests. A simple urine test could one day be an effective way to screen for breast cancer, a new study suggests.
Computer-Aided Mammogram Reading Effective
Detection rates rival those of two radiologist readings, study says. When it comes to reading mammogram results, two heads aren't always better than one.
Birth Size Linked to Breast Cancer Risk
Heavier, longer infants more likely to develop disease as adults, study finds. Women who are heavier and longer at birth are at increased risk of developing breast cancer later in life, British researchers report.
Hypnosis Cuts Hot Flashes for Breast Cancer Survivors
Patients using the technique saw episodes diminish by 68%, study finds. Breast cancer survivors who suffer from hot flashes can reduce these attacks significantly with hypnosis, a new study finds.
Early Breast Cancer No More Likely to Return in Young Women
Findings debunk theory that DCIS recurrence varies with age. Young women diagnosed with a common form of early-stage breast cancer called ductal carcinoma in situ (DCIS) are no more likely to have recurrences than older women with the disease, a new study finds.
Hormone Rx May Protect Women With Breast Cancer Gene
Patients with BRCA mutations cut their odds for malignancy when taking estrogen, study found Postmenopausal women carrying breast cancer-linked BRCA gene mutations who took hormone replacement therapy actually reduced their risk for breast cancer, researchers report.
Shorter-Course Radiation for Breast Cancer Safe, Effective
New findings in cancer radiology also support 'seed' therapy for breast cancer, and a proton beam technique. A more intense but briefer course of radiation therapy is equally effective as the traditional longer course for certain breast cancer patients, Canadian researchers report.
Acupuncture Eases Breast Cancer Treatment Side Effects
Ancient therapy bested antidepressant for relieving hot flashes in study. Lifesaving treatments for breast cancer come at a cost -- many women experience hot flashes, fatigue, night sweats and more.
Breast Cancer Survivors Report High Quality of Life After Treatment
Even 15 years after lumpectomy, radiation, less than 5% complain of pain, survey finds. Women who had a lumpectomy and radiation to combat breast cancer have an overall quality of life several years after treatment that's on par with most adult American women, a new report says.
Drug Combo Fights Recurrent Ovarian Cancer Cell Growth
Researchers say trabectedin showed promise in Phase III trial, hope for FDA approval. The anti-cancer drug trabectedin shows promise in treating women with recurrent ovarian cancer, according to a study led by researchers at the University of California, Irvine.
Lifestyle Changes Boost Enzyme Regulating Cell Aging
Adjustments to diet, exercise increased telomerase levels 29%, cut 'bad' cholesterol. Major lifestyle changes can help improve levels of an enzyme called telomerase that controls cell aging, say California researchers.
Immune System Biomarkers May Predict Early Lung Cancer
A test that uses immune system biomarkers to detect lung cancer can identify the presence of the disease a year before diagnosis, long before a patient experiences any symptoms, according to researchers at the Fred Hutchinson Cancer Research Center in Seattle and the University of Michigan.
Breast Cancer Vaccine Blasts Some Tumors
In animal studies, it eliminated aggressive growths. An experimental breast cancer vaccine eliminated tumors in laboratory animals and may someday help prevent cancer recurrence or help treat women with treatment-resistant forms of breast cancer.
MRIs Don't Improve Breast Cancer Care, Outcome
Study finds getting one delays treatment, raises odds of mastectomy. Women who receive an MRI after a new diagnosis of breast cancer not only delay the start of treatment, but they are also more likely to have a mastectomy, as opposed to breast-conserving surgery.
Drug Re-Sensitizes Breast Tumors to Treatment
Phase II study finds sorafenib helps reverse disease resistance to anti-hormonal therapy. The drug sorafenib may help "re-sensitize" certain breast cancer tumors to anti-hormonal drugs, Georgetown University Medical Center researchers say.
New Screening Catches More Breast Cancers
Finding among new trends in breast cancer diagnosis, treatment, experts say. While tremendous progress in screening and treatment for breast cancer has been made in recent years, some 184,000 new cases of breast cancer will be diagnosed in the United States in 2008, and about 41,000 women will die of the disease.
Breast Cancer Drug Not Tied to Cognitive Decline
Study
Researchers say finding is 'good news' for postmenopausal women taking anastrozole. Contrary to previous study results, the cancer prevention drug anastrozole does not appear to cause impairment of cognitive performance, a new study found.
Normal Cells May Predict Cancer Virulence
Finding suggests that treatment that only aims at malignant cells might fall short. Characteristics of normal cells which are present long before any tumor appears may determine how virulent a particular cancer is going to be, new research suggests.
Drug Stops Bone Loss From Breast Cancer Chemo
Zoledronic acid stabilized mineral density in premenopausal women, study finds. Zometa (zoledronic acid) prevented bone loss at 12 months in premenopausal women undergoing chemotherapy after they had surgery for early stage breast cancer, a new study found.
Zoledronic Acid Protects Bones of Women Getting Breast Cancer Treatment
Drug countered effect of endocrine therapy in premenopausal patients, study finds. Zoledronic acid prevents bone loss in breast cancer patients undergoing endocrine therapy and improves bone mineral density after treatment, according to an Austrian study.
Imaging System Lets Doctors 'See' Cancer During Surgery
Fluorescent dyes light up diseased tissue on video monitors, helping spare healthy cells. A new imaging system that highlights cancerous tissue makes it easier for surgeons to detect and remove tumors without harming surrounding healthy tissue, according to U.S. researchers.
New Imaging Technique Could Spot Early Cancers
Lasers heat nanotubes, then docs listen for ultrasound waves released showing tumors. Nanotechnology may offer doctors a noninvasive way to detect early stages of cancer and also help monitor treatment, a new report says.
HRT Drug Boosts Stroke Risk in Older Women
Tibolone should not be used by those 60 and older, study says. Women 60 and older taking the hormone-replacement therapy drug tibolone to relieve menopausal symptoms are at an increased risk for stroke, a new study finds.
Postmenopausal Women With Breast Cancer Face Joint Issues
Obesity, previous HRT, chemo also raised chances for those on endocrine treatment, study says. Postmenopausal women with breast cancer who are receiving endocrine treatment may be at increased risk of joint issues, including arthritis, a new study finds.
Risk of Breast Cancer Relapse Can Linger
Study shows recurrence after five-year mark, but numbers aren't as high as some might suspect, study says. The risk of relapse can linger for some breast cancer survivors even after completing five years of what doctors call systemic therapy, a new study found.
2 New Genes Tied to 3 Cancers
Finding could improve early detection of breast, thyroid and kidney diseases, researchers say, Two genes linked to breast, thyroid and kidney cancer have been identified by Cleveland Clinic researchers. The discovery of the genes SDHB and SDHD could help improve early detection of these cancers and boost patients' chances of survival.
Breaking the News About Breast Cancer
Women worry about reactions during a time that's already difficult, study finds. Shelley Volz, now 59, got the news about her breast cancer diagnosis 10 years ago, right before she was headed from San Francisco to New York for the wedding of her younger brother.
Experimental Imaging System Helps Detect Breast Cancer
Breast Cancer Vaccines Look Promising
Poorer Patients Have Poorer Survival After Cancer Diagnosis
New Molecule Discovery Shows Promise Against Tamoxifen-Resistant Breast Cancers
Primary Tumors Fuel Growth of Cancer Cells
Facility Characteristics Influence Mammography Accuracy
Raloxifene Cuts Risk of Certain Type of Breast Cancer
Researchers Update Risk-of-Death Charts
Medicare Costs for Cancer Treatment Soar
Avastin Added to Chemo Helps Women With Advanced Breast Cancer
Bone Drug Lowers Risk of Breast Cancer Recurrence
Chemo May Limit Fertility in Breast Cancer Survivors
Initiative Links Celebrities to Cancer Research
Paclitaxel Plus Chemo Improves Outcomes in Early Breast Cancer
Hormone Therapy Safe, Effective for Women Entering Menopause
Mastectomies on the Increase
Blood Test Helps Docs Assess Breast Cancer Treatment
Low Levels of Vitamin D Spell Trouble for Breast Cancer Patients
Hot Flashes Reduced by Neck Injection
Coupled With Mammography, Ultrasound Finds More Breast Cancers
Familial Breast Cancer Risk Lasts a Lifetime for Sisters
Mood Disorders Put Breast Cancer Patients at Risk for PTSD
Breast Cancer Tends to Grow Faster in Younger Women
BRCA Mutations Don't Spot All High-Risk Women
New Targets Found That Stop Tumor Growth
Daily Aspirin May Reduce Breast Cancer Risk
Medicare Costs Soar for Cancer Care
Gene Predicts Breast Cancer Prognosis
Mammograms Still a Good Idea for Elderly Women
Many Cancer Survivors Are Overweight and Sedentary
Study
Weekly Doses of Taxol Prolonged Lives of Breast Cancer Patients
Chemo May Not Affect Memory in Breast Cancer Patients
Breast Cancer Unchanged in Black Women, Despite Drop in HRT Use
Women's Awareness of Cancer Risk Linked to Race, Ethnicity
Detecting, Diagnosing Breast Cancers
Stem Cell Marker Controls Pair of Key Cancer Pathways
Breast Cancer Vaccine Works Against Deadlier Form of Disease
Drinking May Raise Breast Cancer Risk
Doctor-Patient Talks Affect Use of Breast Reconstruction Surgery
Breast Cancer Lymph Node Biopsy May Need Closer Look
Estrogen Supplements May Raise Odds of Benign Breast Disease
Anemia Triples Risk of Local Recurrence in Breast Cancer Patients
Molecular Cause of Breast Cancer Metastasis Discovered
Genomic Profiling of Breast Cancers a Better Treatment Tool
Many Women Unclear About Breast Cancer Treatments
Gaps Persist in Use of Less Invasive Breast Cancer Procedure
HRT Raises Recurrence Risk Among Breast Cancer Survivors
Obese Women Less Likely to Be Tested for Some Cancers
Family Discussion Plays Role in Breast Cancer Awareness
Cancer Poses Challenges for Husbands' Frame of Mind
Environmental Toxins, Radiation May Be Tied to Breast Cancer
Breast Cancer Radiation Therapy Works in Fewer, But Higher Doses
Obesity Linked to Poor Prognosis for Some Breast Cancer Patients
FDA Panel Supports Anemia Drugs for Cancer Patients
Doctors See How Cancer Drug Can Damage Kidneys
'Crime Boss' Gene May Spur Breast Cancer
Finding might explain why some tumors are aggressive and spread, researchers say. Scientists have identified a gene they say can promote aggressive breast cancer by acting as a kind of "crime boss," capable of changing the behavior of more than 1,000 genes within tumor cells.
Late Use of Aromatase Inhibitor Still Effective Against Breast Cancer
Yoga Eases Menopause Symptoms in Breast Cancer Survivors
Estrogen Levels in Blood Predict Breast Cancer's Return
Raised Breast Cancer Risk Persists After Combo HRT Stopped
Embryonic Stem Cell Protein Inhibits Melanoma
Breast Cancer Drug Might Treat Bipolar Disorder
Heart Hormones Beat Back Cancers in Mice
Cost of Breast Cancer Can Include Paycheck
HRT Can Lead to Abnormal Mammograms, Biopsies
FDA OKs Avastin for Advanced Breast Cancer
Timely Cancer Diagnosis Linked to Insurance Status
Chemotherapy After Breast Cancer Surgery Effective for Older Women, Too
Obesity Raises Cancer Risk
DDT Compound Speeds Breast Cancer Growth
Precancerous Breast Lesions Cause Unnecessary Worry
Ovary Removal Protects Some High-Risk Women
Most Breast Cancer Web Pages Contain Reliable Information
Pathology Reports Good for Breast Cancer Studies
Personality Traits Don't Affect Breast Cancer Risk
Protein Linked With Poor Prognosis in Early-Stage Breast Cancer
Surgeons' Characteristics Influence Breast Cancer Care
Next Generation of Parents More Likely to Back Genetic Testing
Implants Double Infection Risk After Breast Reconstruction
Biological Link Between BRCA1 and Breast Cancer Detailed
HRT Raises Risk of Lobular Breast Cancer
Genetic Breast Cancer Test Approved
Vaccines for Ovarian and Breast Cancer in Early Trials
Tiny RNA Molecules Control Breast Cancer's Spread
BRCA Mutations Don't Raise Breast Cancer Risk Equally
Localized Breast Cancer Cells Have Potential to Spread
Not All Women Need Digital Mammograms
Breast Cancer Gene Might Extend Ovarian Cancer Survival
Class of Chemotherapy Drugs Helps Certain Breast Cancer Patients
BRCA1 Mutation Prevalent Among Hispanic, Younger Black Women
Low-Income Women's Cancer Screenings Cost Effective
Report
Breast Cancer Surgeons Don't Discuss Reconstruction Options
Hormone Could Ease Painful Lymphedema
Uninsured More Likely to Die From Cancer Following Diagnosis
Area Around Breast Tumor May Predict Cancer's Spread
Cancer Care Advances in 2007 Offer Hope
Cancer Killed Almost 8 Million Worldwide in 2007
Even Tiny Breast Tumors May Need Aggressive Treatment
Arimidex Beats Tamoxifen in Keeping Breast Cancer at Bay
Breast Cancer Genes Also Raise Men's Risk for Malignancy
High-Dose Chemo Provides Little Benefit to Breast Cancer Patients
Diagnostic Mammogram Readings Vary by Radiologist
Mutated Suppressor Gene Leads to a Type of Breast Cancer
Obesity, Diabetes Linked to Cancers
Common Household Chemical Could Raise Breast Cancer Risk
Black Women Wait Longer for Breast Cancer Surgery
FDA Panel Says No to Avastin for Advanced Breast Cancer
Night Shift Work May Heighten Risk for Cancer
Diets May Raise Cancer Risk for Poor, Urban Women
Studies Reveal Why Breast Cancer Hits Black Women Harder
Fewer Women Getting Mammograms
3-D Breast Imaging May Improve Cancer Detection
Combo PET/CT Scan Helps Spot Breast Cancer's Spread
Non-White Women More Prone to Breast Cancer Pain
Understanding of Mammography Differs Among Races
Urban Women May Have Greater Breast Cancer Risk
Cannabis Compound May Stop Metastatic Breast Cancer
Cell Insights May Predict Breast Cancer's Spread
Excess Pounds Raise Women's Cancer Risk
Little Evidence Silicone Breast Implants Harm Health
Smoking Does Not Worsen Breast Cancer
Survey Finds Many Women Misinformed About Cancer
More Women Choosing 'Preventive' Double Mastectomy
Best Breast-Cancer Care Eludes Older Women
Protein Gives Clues to Pancreatic Cancer
Ixempra Approved for Breast Cancer
U.S. Cancer Death Rate Continues to Fall
Breast Cancer Radiation Won't Hurt Immune Health
Drug a New Weapon Against One Form of Breast Cancer
Woman's Hips Might Indicate Daughter's Breast Cancer Risk
Black Women Get Less Breast Cancer Treatment
Wine, Beer, Spirits Boost Breast Cancer Risk Equally
1 in 12 Outpatient Visits Is for Prevention
Study
In the United States, preventive health exams account for about 1 in 12 adult outpatient visits to doctors, says a study that found that, each year between 2002 and 2004, about 63.5 million adults had a preventive health or gynecological check-up, at an annual cost of $7.8 billion.
Breast Cancer Death Rates Continue to Fall
Experts Offer Tips on Easing Mammogram Discomfort
Gene May Influence Breast Cancer-Estrogen Link
FDA Approves Osteoporosis Drug to Cut Breast Cancer Risk
Osteoporosis Drug Evista Approved to Cut Risk of Breast Cancer
Tamoxifen Helps Treat Bipolar Disorder
Education Linked to Cancer Death Rates
Workouts a Boon for Breast Cancer Patients
Studies Shed New Light on Breast Cancer, Treatment
Hypnosis Eases Pain of Breast Cancer Surgery
Acrylamide Won't Raise Breast Cancer Risk
Many Parents Share Genetic Test Findings With Kids
Healthy Lifestyle Key To Cancer Prevention
Decline in U.S. Breast Cancers Tied to Drop in Hormone Use
Scientists Create Breast Tumor Stem Cells
MRI Beats Mammograms at Spotting Early Breast Cancer
Cosmetic Breast Surgeries Tied to Increased Suicide Risk
Breast CT Scans Could Be Comfortable Alternative to Mammograms
For women who find traditional mammograms painful, new research suggests there may one day be a more comfortable alternative. Breast CT scans showed some advantages over traditional mammograms
2 Breast Cancer Screening Strategies Prove Effective
A study in the July 29 online issue of the Journal of the National Cancer Institute finds that a traditional physician- and self-referral screening strategy held up well against the Norway approach, in which the government sends letters to all women in a specific age range inviting them to have a screening mammogram.
Bone Density Predicts Chances of Breast Cancer
Calculating a woman's bone mineral density appears to shed light on her risk for breast cancer. A new study has found that high bone mineral density (BMD) predicts a greater likelihood of developing breast cancer, independent of how high her risk is on the often-used Gail model.
Cancer Survival Depends on Where You Live
U.S. does better than Europe, although American whites do better than blacks, study finds. Your odds of surviving cancer depend on which country you live in. And, in the United States, it also depends on whether you're black or white, a new study finds.
No Evidence Breast Self-Exams Cut Cancer Deaths
Review of studies says monthly check is 'an option' for women starting in their 20s. Updated findings from an analysis of existing research continue to suggest that the oft-touted monthly breast self-exam may actually do more harm than good.
Recent Genetic Discoveries Don't Improve Prediction of Breast Cancer
When added to risk assessment tool, SNPs made no difference, study finds. The accuracy of predicting one's chances of developing breast cancer do not seem to improve even with the recent findings of some genetic markers for the disease, a new report says.
Men Often Not Told of Severity of Wife's Cancer
Study finds almost 40% say docs never said condition was terminal until near death. A new Swedish study reports that two in five widowers were never told their wives' cancer was incurable until she was near death, if they were told at all.
Gene Activity May Explain Deadlier Breast Cancers Among Younger Women
Study finds more than 350 common sets of genes in patients under 45. Genetic activity in breast cancer cells from younger patients could explain why tumors tend to more aggressive when they strike at a younger age.
Breast-Conserving Surgery Leaves Many Cancer Patients Disappointed
Poor aesthetic outcome after lumpectomy linked to depression, fear, study finds. A third of women who opt for breast-conserving cancer surgery say they now have an asymmetry between their breasts that greatly affects their quality of life, a new study says.
Breast Cancer Test Rates Drug Therapy Candidates
Helps doctors make better treatment decisions. The U.S. Food and Drug Administration has approved a genetic test designed to evaluate whether a person with breast cancer is a good candidate for treatment with the drug Herceptin (trastuzumab).
FDA Approves Genetic Test for Breast Cancer
Kit will help identify which patients are most likely to respond to Herceptin. A genetic test to determine whether a breast cancer patient is likely to respond to treatment with the drug Herceptin (trastuzumab) has been approved by the U.S. Food and Drug Administration.
Dietary Supplement May Prevent Breast Cancer
Resveratrol, found in red wine, grape skins, inhibits abnormal cells, study finds. A compound found in red grapes and red wine suppresses abnormal cell formation that leads to most types of breast cancer, according to U.S. researchers.
Paclitaxel Plus Chemo Improves Outcomes in Early Breast Cancer
Study finds a trend toward better overall survival
The phase III trial included 1,246 women with early, non-metastatic breast cancer who were randomly assigned to receive treatment




